<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19769

Description Serine/threonine-protein kinase
SequenceMMASRSEIVEEPPPEQVVEDKIYVAVGKDLKESKLTLSWALHTSGGRKLCILYVLEPAQRIPLLGTKFLPSQLEEHQVRAYRETERQDMNKLLRDYSMICERAGVRADVLHIEMDSIEKGIVELISQNRIRKLVMGAAADKHYSKKMMEPKSKKAIYVRLQAPMSCHIWFICKGNLVHTREGRLEGVRMEFASVTLRASPNTESGQTSYLRSQSVAGKNNQLKLISVGRDHRRGWSDIHGMNVSTFSPDSSGGITPRSNSSAEVNFSDWDEISRSSSLTSRLLSCSSGDMADYSDLTSAARAEAQLESQALHHSKEEHHQYSSPPSVLEGGMNDELYDQLEQAMAEAENSRREAFEESTRRRKAEKDAIDAVRRAKTSETLYVEVSRQRKEIEEALARGKEELEKMKKQADEVMEELRLALVHKSSLESQIASSKQMVQDLEDKMFSAVDLLQKYKKERDELQVERDNALKVAEDLRKKQAEEASQSVMPQFFSEFSFSEIEAATTSFDPSLKIGEGGYGSIYRGFLRHTQVAIKMLHSHSLQGPSEFQQEVNILSKLRHPNLVTLVGACPEAWILVYEYLPNGSLEDRLSCRDNTSPLSWQARIRIATELCSVLIFLHSCNPHSVVHGDLKPANILLDANLVSKLSDFGICRVITQNELSSNNTTLCCITDPKGTFAYMDPEFLSTGELTPMSDVYSFGIILLRLLTGQPALGITKEVQYALDKGNLKDLLDPTAGDWPFVQAKQLAHLAIRCCEMSRKSRPELASDVWRVLEPMRVSCGASSFRMSSEEHCQIPSYFICPIFQEIMQDPHIAADGFTYELEALKGWLDSGHDTSPMTNLKLSHCNLVPNRALRSAIQEWLQQR
Length865
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.06
Grand average of hydropathy-0.432
Instability index53.52
Isoelectric point5.94
Molecular weight97462.71
Publications
PubMed=29661190

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19769
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.80|      37|      46|     367|     412|       1
---------------------------------------------------------------------------
  376-  412 (58.09/36.56)	KTSETLYVEVSRQR.KEIEEALARGKEELEKMKKQADE
  424-  461 (53.71/20.82)	KSSLESQIASSKQMvQDLEDKMFSAVDLLQKYKKERDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.03|      40|      45|     270|     314|       2
---------------------------------------------------------------------------
  270-  314 (57.89/50.01)	DEISRSSSLTSRLlscsSGDMAD..YSDLTSA.ARAEAQlESQALHHS
  316-  358 (63.14/39.40)	EEHHQYSSPPSVL....EGGMNDelYDQLEQAmAEAENS.RREAFEES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.35|      35|      50|     609|     657|       3
---------------------------------------------------------------------------
  609-  656 (54.35/58.35)	TELCSVL....IFLHsCNPHSVVHGDLKPanilldanlvskLSD...FGI..CRVIT
  665-  708 (51.00/26.64)	TTLCCITdpkgTFAY.MDPEFLSTGELTP............MSDvysFGIilLRLLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.22|      47|      51|     763|     809|       4
---------------------------------------------------------------------------
  763-  809 (88.09/52.71)	PELASDVWRV.LEPMR..VSCGASSFRMSSEE..HCQ.IPSYFICPIFQEIMQ
  811-  863 (66.14/37.85)	PHIAADGFTYeLEALKgwLDSGHDTSPMTNLKlsHCNlVPNRALRSAIQEWLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.36|      36|      50|     476|     512|       6
---------------------------------------------------------------------------
  476-  512 (56.13/41.93)	LRKKQ.AEEASQSVMPQFFSEFSfSEIEAATTSFDPSL
  527-  563 (58.23/38.28)	LRHTQvAIKMLHSHSLQGPSEFQ.QEVNILSKLRHPNL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19769 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) YSDLTSAARAEAQLESQALHHSKEEHHQYSSPPSVLEGGMNDELYDQLEQAMAEAENSRREAFEESTRRRKAEKDAIDA
293
371










Molecular Recognition Features






MoRF SequenceStartStop




NANANA