<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19768

Description Mediator of RNA polymerase II transcription subunit like
SequenceMQRYHAPSCTSAVNNSAIGGTSARDTSRVDPSSLSTNFSLTQRRVPQLTSYKLKCDKEPLNSRLGPPDFHPQTPNCPEETLTREYVQSGYRETVEGLEEAKEISPSQIQTFTKPVILKCKEAIRKCHRAINESRTQKRKAGQVYGVTLSGTLLTKPGVFPEQRPCGEDFRRKWIEEKDLLGTLQLLLPILYGVIESVVLSQTYVRTVVGLAVRFIQEPSPGGSHLVDNSRRAYTTSAMVEMLRYMILAVPDTFVALDCFPLPPCVVSHVVNDGNFLSKVSDGTAKINSGSVEVGVLLKEKVIEPQHQSFSIDCVVSSIQKCANNLAMAARPGYPGRSVAKAVQELDKALVQGDVRMAYSVLFNDLCEGAVDEGWVAEVSPCLRSSSKWIGMVSLSFVCSVFFLCEWATCDFRDFRNAPPCGMKFTGRKDFSQVYLAIQLLMLKIKDMQSSLSCKNDGTRGVNSLAKGPGQLNNYSGRNFVGTGNEHKSNSRSVVKSKELSNIFESPGPLHDIIVCWLDQHEVQNGEGFKRLQLLIVELTRSGIFYPQAYVRQLIVSGIMDGNGLPVDIDRRKRHYKILKQLPGSYIRDALEEAQITEMPVLLEATNVYSNERRLLLNGLIDHPKNPNNANISSKKQKYHLISGGDGAPSQSVDQWRTLQPSSRLSGKSSNRIADIEELKTAISMLLQLPNVSCTSTEIGIDESQGSVKGLGGSTSDITDLGEGTPGCEECRRAKRQKLSDERSSYVQGNSGNLLDGEEIWWVRKGLKPMEALKTDPPLKPAKQSSRGRQKIVRKTQTLAQLGSARIEGSQGASTSHVCDSRVSCPHHGIGFDGETPKSMCGIRTSHSGDIVSIGKILKQLRFVEKRFITIWLVTVVRQLVEENDKAAAKVGQYGRPFPSVDDKTSLRWKLGEDELSAILYLIDVSNDLVSAARFLLWLLPKVLGSPSSTIHGGRNILMLPRNVGTHVCEVGEAFLLSSIRRYENILVATELLPETLSAMMQRATTVLASNGRVSGSVSLVYARYLLKKYGSVASVVEWEKNFKATCDKRLLPELESGRSLDGELVLPLGVPAGVEDLDDFLRQKISGGRVSRVGLSMRDMVHRQVEEAVQYFYSKERKLFTAGMIKGPTLEKGDDVYQMAQQIVIGLMDCMRQTGGAAQEGDPSLVSSAVSAIFNSIGPVVAKLPDLTASGNHPNFPSPAGSLTFARRILRSHITCLYLLKEALGERQSRVFEIALATEASSALAQAFAPGKAPRGQFQLSPEAHDSNANSSNEHMNSSAKTGKAAKIAAAVSALVIGAILHGVASLERMVTVFKLKEGLDVIQFLRTTRSNSNGNARSVGAFKADNVVEISAHWFRVLVGNCRTVSDGLIVDLLGEVSVVALSRMQRTLPLSLVFPPAYSIFAFVIWRPFIFNTSIITREDVHHLYQCLAFAIGDAIKHLPFRDVCLRDTRGFYDLVVADATDSEFAVMLELNGAEMHMKVMAFIPLRARLFLNAIIDCKMPQSMSTQDDGNRVGESVVQYAENETKLLDKLVHVLDKLQPAKFHWQWVELRLLLNEQALIEKLDSHDTSLAEAIHSAYPNPDKAAASENENNFIQIILTRLLVRPDAAPLFSEVIHLFGRSLEDSMLLQAKWFLGGLDVLFGRKSIRQRLINIAESKGLSTKAHFQKPWGWCCSNSDLLSSKEDMRKFETSSLEEGEVVEEGAELKRLGRGSTQGLDVEGSNICQQYITERALIELVLSCIDQSSDDSRSTFASDLIKQMSNIEQQINAVTRGATKQGGAVNSGSEGTGTKNNNRKGLRGGSPGLARRSTVTADIVPPSPVALRASMSLRLQFLVRLLPIICADGEPSARNLRHMLASVVLRLLGSRVVHEVVEQSLFPMLSSSLKVDVDLSMEAFAPAAVDLSGESLFNRLLLVLHGLLGSSRPRWLKSKKDFSVFDFEVADSLQNDLDRMHLPDSIRWRIQAAMPSLFPSFRWHISCQPPSVSPAALASLQPIISVSGSHPGNSNLAQRIPGSSSTRTATSLVGKTKPSPLQQDIDMEIDPWTLLEDGAGSGPSSTSTSGIGGSDNANLRASSLLKGAVRVRRTDLTYIGVVDDDS
Length2100
PositionKinase
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.06
Grand average of hydropathy-0.175
Instability index46.28
Isoelectric point8.52
Molecular weight230305.85
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19768
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     368.15|     117|     278|     576|     699|       1
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  576-  689 (154.14/120.16)	..................................KILKQLpgSYIrdalEEAQITEMPVLLEATNVYSNERRLLLNGLIDHPkNPNNAN......................................ISSKKQK.........YHLIS.GGDGAPSQSVDQW...RTLQPSSRLSGK..........................SSNRIADIEELKTAISMLLQLP
  690-  820 (61.91/35.04)	NVSCTSTEIG...............................................................................idesqgsvkglggstsditdlgegtpgceecrrakrqkLSDERSS.........Y..VQ.GNSGNLLDGEEIWwvrKGLKPMEALKTDpplkpakqssrgrqkivrktqtlaqlGSAR...IEGSQGASTSHVCDS
  821-  960 (152.10/98.82)	RVSCPHHGIGfdgetpksmcgirtshsgdivsigKILKQL..RFV....EKRFITIWLVTVVRQLVEENDKAAAKVGQYGRP.FPSVDD......................................KTSLRWKlgedelsaiLYLIDvSNDLVSAARFLLW.....LLP..KVLGS..........................PSSTIHGGRN.......ILMLP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     413.06|     161|     977|      89|     406|       2
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   89-  223 (170.28/301.10)	GYRETVEGLEE..AKEISPSQIQTftkpVILKCKEAI.RKCHRAINESRTQKRK...AGQVYGVTL.SGTLLTKpgvFPEQRPCG.EDFRRKwIEEKDLLGTLQLLLPILYGVIESV..VLSQTYVRTVVGLAVRFiqePSPGGS.................................................................................................................
  296-  336 ( 6.97/106.39)	.................................................................................................................................................hlvdnsrrayttsamvemlrymilavpdtfvaldcfplppcvvshvvndgnflskvsdgtakinsgsvevgvLLKEKVIEPQHQSFSIDCVVSSiqkcANNLAMAARPGYPGR
 1069- 1255 (235.81/ 0.00)	GVPAGVEDLDDflRQKISGGRVSR....VGLSMRDMVhRQVEEAVQYFYSKERKlftAGMIKGPTLeKGDDVYQ...MAQQIVIGlMDCMRQ.TGGAAQEGDPSLVSSAVSAIFNSIgpVVAKLPDLTASGNHPNF...PSPAGS........................................................ltfarrilrshitclyLLKEALGERQSRVFEIALATEA....SSALAQAFAPGKAPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.76|      20|     278|    1351|    1371|       3
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 1351- 1371 (32.05/24.26)	ISAHWF....RVLVGNcRTVSDGLI
 1630- 1653 (30.71/17.10)	LQAKWFlgglDVLFGR.KSIRQRLI
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     237.16|      75|     246|    1763|    1838|       9
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 1763- 1838 (121.08/76.77)	SNIEQQI..NAVTRGATKQGGAVNSG..SEGTGTKNNNRKGLRGGSpGLARRSTVTADIVPPSPVALRASMSLRLQFLVR
 2008- 2086 (116.08/68.78)	SNLAQRIpgSSSTRTATSLVGKTKPSplQQDIDMEIDPWTLLEDGA.GSGPSSTSTSGIGGSDNANLRASSLLKGAVRVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.77|      31|     981|     364|     406|      12
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  365-  398 (49.27/59.64)	LCEGAVDEGWvAEVSPCLRSSSKwiGM.VSLSFVC
 1695- 1726 (49.51/21.66)	LEEGEVVEEG.AELKRLGRGSTQ..GLdVEGSNIC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19768 with Med12 domain of Kingdom Viridiplantae
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