<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19768

Description Mediator of RNA polymerase II transcription subunit like
SequenceMQRYHAPSCTSAVNNSAIGGTSARDTSRVDPSSLSTNFSLTQRRVPQLTSYKLKCDKEPLNSRLGPPDFHPQTPNCPEETLTREYVQSGYRETVEGLEEAKEISPSQIQTFTKPVILKCKEAIRKCHRAINESRTQKRKAGQVYGVTLSGTLLTKPGVFPEQRPCGEDFRRKWIEEKDLLGTLQLLLPILYGVIESVVLSQTYVRTVVGLAVRFIQEPSPGGSHLVDNSRRAYTTSAMVEMLRYMILAVPDTFVALDCFPLPPCVVSHVVNDGNFLSKVSDGTAKINSGSVEVGVLLKEKVIEPQHQSFSIDCVVSSIQKCANNLAMAARPGYPGRSVAKAVQELDKALVQGDVRMAYSVLFNDLCEGAVDEGWVAEVSPCLRSSSKWIGMVSLSFVCSVFFLCEWATCDFRDFRNAPPCGMKFTGRKDFSQVYLAIQLLMLKIKDMQSSLSCKNDGTRGVNSLAKGPGQLNNYSGRNFVGTGNEHKSNSRSVVKSKELSNIFESPGPLHDIIVCWLDQHEVQNGEGFKRLQLLIVELTRSGIFYPQAYVRQLIVSGIMDGNGLPVDIDRRKRHYKILKQLPGSYIRDALEEAQITEMPVLLEATNVYSNERRLLLNGLIDHPKNPNNANISSKKQKYHLISGGDGAPSQSVDQWRTLQPSSRLSGKSSNRIADIEELKTAISMLLQLPNVSCTSTEIGIDESQGSVKGLGGSTSDITDLGEGTPGCEECRRAKRQKLSDERSSYVQGNSGNLLDGEEIWWVRKGLKPMEALKTDPPLKPAKQSSRGRQKIVRKTQTLAQLGSARIEGSQGASTSHVCDSRVSCPHHGIGFDGETPKSMCGIRTSHSGDIVSIGKILKQLRFVEKRFITIWLVTVVRQLVEENDKAAAKVGQYGRPFPSVDDKTSLRWKLGEDELSAILYLIDVSNDLVSAARFLLWLLPKVLGSPSSTIHGGRNILMLPRNVGTHVCEVGEAFLLSSIRRYENILVATELLPETLSAMMQRATTVLASNGRVSGSVSLVYARYLLKKYGSVASVVEWEKNFKATCDKRLLPELESGRSLDGELVLPLGVPAGVEDLDDFLRQKISGGRVSRVGLSMRDMVHRQVEEAVQYFYSKERKLFTAGMIKGPTLEKGDDVYQMAQQIVIGLMDCMRQTGGAAQEGDPSLVSSAVSAIFNSIGPVVAKLPDLTASGNHPNFPSPAGSLTFARRILRSHITCLYLLKEALGERQSRVFEIALATEASSALAQAFAPGKAPRGQFQLSPEAHDSNANSSNEHMNSSAKTGKAAKIAAAVSALVIGAILHGVASLERMVTVFKLKEGLDVIQFLRTTRSNSNGNARSVGAFKADNVVEISAHWFRVLVGNCRTVSDGLIVDLLGEVSVVALSRMQRTLPLSLVFPPAYSIFAFVIWRPFIFNTSIITREDVHHLYQCLAFAIGDAIKHLPFRDVCLRDTRGFYDLVVADATDSEFAVMLELNGAEMHMKVMAFIPLRARLFLNAIIDCKMPQSMSTQDDGNRVGESVVQYAENETKLLDKLVHVLDKLQPAKFHWQWVELRLLLNEQALIEKLDSHDTSLAEAIHSAYPNPDKAAASENENNFIQIILTRLLVRPDAAPLFSEVIHLFGRSLEDSMLLQAKWFLGGLDVLFGRKSIRQRLINIAESKGLSTKAHFQKPWGWCCSNSDLLSSKEDMRKFETSSLEEGEVVEEGAELKRLGRGSTQGLDVEGSNICQQYITERALIELVLSCIDQSSDDSRSTFASDLIKQMSNIEQQINAVTRGATKQGGAVNSGSEGTGTKNNNRKGLRGGSPGLARRSTVTADIVPPSPVALRASMSLRLQFLVRLLPIICADGEPSARNLRHMLASVVLRLLGSRVVHEVVEQSLFPMLSSSLKVDVDLSMEAFAPAAVDLSGESLFNRLLLVLHGLLGSSRPRWLKSKKDFSVFDFEVADSLQNDLDRMHLPDSIRWRIQAAMPSLFPSFRWHISCQPPSVSPAALASLQPIISVSGSHPGNSNLAQRIPGSSSTRTATSLVGKTKPSPLQQDIDMEIDPWTLLEDGAGSGPSSTSTSGIGGSDNANLRASSLLKGAVRVRRTDLTYIGVVDDDS
Length2100
PositionKinase
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.06
Grand average of hydropathy-0.175
Instability index46.28
Isoelectric point8.52
Molecular weight230305.85
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19768
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     368.15|     117|     278|     576|     699|       1
---------------------------------------------------------------------------
  576-  689 (154.14/120.16)	..................................KILKQLpgSYIrdalEEAQITEMPVLLEATNVYSNERRLLLNGLIDHPkNPNNAN......................................ISSKKQK.........YHLIS.GGDGAPSQSVDQW...RTLQPSSRLSGK..........................SSNRIADIEELKTAISMLLQLP
  690-  820 (61.91/35.04)	NVSCTSTEIG...............................................................................idesqgsvkglggstsditdlgegtpgceecrrakrqkLSDERSS.........Y..VQ.GNSGNLLDGEEIWwvrKGLKPMEALKTDpplkpakqssrgrqkivrktqtlaqlGSAR...IEGSQGASTSHVCDS
  821-  960 (152.10/98.82)	RVSCPHHGIGfdgetpksmcgirtshsgdivsigKILKQL..RFV....EKRFITIWLVTVVRQLVEENDKAAAKVGQYGRP.FPSVDD......................................KTSLRWKlgedelsaiLYLIDvSNDLVSAARFLLW.....LLP..KVLGS..........................PSSTIHGGRN.......ILMLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     413.06|     161|     977|      89|     406|       2
---------------------------------------------------------------------------
   89-  223 (170.28/301.10)	GYRETVEGLEE..AKEISPSQIQTftkpVILKCKEAI.RKCHRAINESRTQKRK...AGQVYGVTL.SGTLLTKpgvFPEQRPCG.EDFRRKwIEEKDLLGTLQLLLPILYGVIESV..VLSQTYVRTVVGLAVRFiqePSPGGS.................................................................................................................
  296-  336 ( 6.97/106.39)	.................................................................................................................................................hlvdnsrrayttsamvemlrymilavpdtfvaldcfplppcvvshvvndgnflskvsdgtakinsgsvevgvLLKEKVIEPQHQSFSIDCVVSSiqkcANNLAMAARPGYPGR
 1069- 1255 (235.81/ 0.00)	GVPAGVEDLDDflRQKISGGRVSR....VGLSMRDMVhRQVEEAVQYFYSKERKlftAGMIKGPTLeKGDDVYQ...MAQQIVIGlMDCMRQ.TGGAAQEGDPSLVSSAVSAIFNSIgpVVAKLPDLTASGNHPNF...PSPAGS........................................................ltfarrilrshitclyLLKEALGERQSRVFEIALATEA....SSALAQAFAPGKAPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.76|      20|     278|    1351|    1371|       3
---------------------------------------------------------------------------
 1351- 1371 (32.05/24.26)	ISAHWF....RVLVGNcRTVSDGLI
 1630- 1653 (30.71/17.10)	LQAKWFlgglDVLFGR.KSIRQRLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     237.16|      75|     246|    1763|    1838|       9
---------------------------------------------------------------------------
 1763- 1838 (121.08/76.77)	SNIEQQI..NAVTRGATKQGGAVNSG..SEGTGTKNNNRKGLRGGSpGLARRSTVTADIVPPSPVALRASMSLRLQFLVR
 2008- 2086 (116.08/68.78)	SNLAQRIpgSSSTRTATSLVGKTKPSplQQDIDMEIDPWTLLEDGA.GSGPSSTSTSGIGGSDNANLRASSLLKGAVRVR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.77|      31|     981|     364|     406|      12
---------------------------------------------------------------------------
  365-  398 (49.27/59.64)	LCEGAVDEGWvAEVSPCLRSSSKwiGM.VSLSFVC
 1695- 1726 (49.51/21.66)	LEEGEVVEEG.AELKRLGRGSTQ..GLdVEGSNIC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19768 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ESQGSVKGLGGSTSDITDLGEGTPGCEECRRAKR
2) SCTSAVNNSAIGGTSARDTSRVDPSSLSTNFSLT
3) SNLAQRIPGSSSTRTATSLVGKTKPSPLQQDIDME
4) TRGATKQGGAVNSGSEGTGTKNNNRKGLRGGSP
702
8
2008
1773
735
41
2042
1805










Molecular Recognition Features






MoRF SequenceStartStop




NANANA