<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19765

Description Cyclin-dependent kinase
SequenceMGDGNNNSRNNNNNNSNSNRPEWLQQYDLIGKIGEGTYGLVFLAKIKSNQSKSIAIKKFKQSKDGDGVSPTAIREIMLLREINHENVVKLVNVHINHGDMSLYLAFDYAEHDLYEIIRHHRDKVNHAINPYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEVEEQGVVKIADFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGQEVKAIPNPFQLDQLDKIFKVLGHPTQEKWPTLVNLPHWQLDVQHIQGHKYDNPGLYTVVHLSPKSPAYDLLSKMLEYDPRKRITAAQALEHEYFRLEPLPGRNALVPSQSGEKVVNYPTRPVDTTTDFEGTTSLQPPQPVSSGNAVSGNMSGPHVMPNRSVPRPMPVGGMQRMQPQGMAAYNLSSQAGMGGMNPGNIPMQRGVAAQAHHHQQMRRKDSGMGMPGYPPQQKSRRF
Length475
PositionKinase
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.08
Grand average of hydropathy-0.495
Instability index42.77
Isoelectric point9.22
Molecular weight53324.31
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19765
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.98|      37|      38|     361|     398|       1
---------------------------------------------------------------------------
  361-  398 (63.11/35.68)	RPVDTTTDFEGTTSLQPpQPVSSGNAVS.GNMSG..PHVMP
  400-  439 (58.87/28.89)	RSVPRPMPVGGMQRMQP.QGMAAYNLSSqAGMGGmnPGNIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.94|      28|      42|     163|     192|       2
---------------------------------------------------------------------------
  163-  192 (42.89/36.15)	LVMGEVEEQGVVKIADFGLarIYQA..PLKPL
  208-  237 (45.05/31.08)	LLLGAKHYTSAVDMWAVGC..IFAEllTLKPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     141.63|      46|     144|     106|     159|       3
---------------------------------------------------------------------------
  106-  159 (77.21/63.38)	FDYAEHD.LYEIIRHH.RDKVNHAIN.PYtvksllWQL....LNGLNYLHSNW..IIHrdLKP
  250-  304 (64.42/37.59)	FQLDQLDkIFKVLGHPtQEKWPTLVNlPH......WQLdvqhIQGHKYDNPGLytVVH..LSP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19765 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LPGRNALVPSQSGEKVVNYPTRPVDTTTDFEGTTSLQPPQPVSSGNAVSGNMSGPHVMPNRSVPRPMPVGGMQRMQPQGMAAYNLSSQAGMGGMNPGNIPMQRGVAAQAHHHQQMRRKDSGMGMPGYPPQQKSRRF
340
475










Molecular Recognition Features






MoRF SequenceStartStop




1) KSIAIKKFK
2) MGMPGYPPQQKSRRF
3) VAAQAHHHQQMRRKD
52
461
444
60
475
458