<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19758

Description Mediator of RNA polymerase II transcription subunit 15a like
SequenceMDTNNWRPAPGGAGEPTMDTGDWRAQLQPDSRQRIVNKIMDTLKRHLPFSGQEGLQELKKIAVRFEEKIYTSATSQPDYLRKISLKMLTMENKSQNTMANSLPSNSASNSKNPADTGSLAMPSQITNQGPSLPIPMAANPGQARQQLLSQNIPNNIAATGIQGSASLTSALPPVGGLPSTTMPNVVGQNSNLQNIQNISGVSQNSVGNPMGQGVSNNIFANTQRQMPGRQQQVATQQQQQQSQNSQHYLYQQQLQQQMMKQKYQQGNIPNTNIQSHLQPQQPHHQQNLLQSNQLQVSQPSIMQPSAQLSGLQQSQSAQTMLQQNPQSVLRQQQQTPIIHQQQTPMQPQTMLPPQQQQQQQQLMGQQPNSTIMQPNQLIGQQNNIPDMQQQQQRLLGQQNSLSNLQQQQQQLMNQQNNLPNQLQQLGPQSNIAALQQRHQHQHQQQQLHVPQSGNSSLQTNQQSIHMLQQSKVPLQQQNQQSAATLLPTQGQQSEPQPLQQQLISQIQSQPGQLQQQALQQHPNSLQQDMQQRLQASGPLVQSQSMIDQQKQLLQPQRAIPEASSTSLDSTAQTGNANSGDWQEDVYQKIKAMKEAYLPELNEMYQKVAGKLQQHDSFPQQPKSEQLEKLKSFKNMLERIIAFLQVSKSNILPGFKDKFRSYETQIINFLNSNRPRKPGPTLQQGQQLPPPHVQSVQQAQQSQSQISQSQPHEIQMNPQLQSVNFQGSVPMMQQSNVANMQHNSLSSLSGVTNTSQSMINSLQPSTNMDSGQGNALNNLQVAVGSLQQNPVNTPQQVTINSLSSHNGMNVLQPNLTPLQSNSNMLQHQHLKQQEQQMLQTQLKQQFQQRQMQQQLMQKQQLLQQQQQQQQQQLHQQTKQQQNVQLQAHQMSQLHQMNDVNDLKMRQQMGVKSGVFQQTHSAGQRAAYHYQQLKSGAPFPISSPQLLQAASPQMLQHASPQIDQQNMLTSLTKSGTPLQSASSPFVVPSPPTPLAPSPMQGESEKVNSGVPTLSNGGNIGHQQTAGAVTPAQSVAIGTPGISASPLLAEFTSPDGNHGNASTVVSGKSSVTEQPLERLIKVVKSMSPKSLSASVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARTIATQDTNAGTRKMKRYTSAIPLNVASSAGSGNDSFKRLTGSEASDLESTATSSIKRPRSEANHALLEEIRGINQRLIDTVVSISEEDVDPTAAAAITAEGGEGTVVRCTFSAVALSPNLKSHYASAQMSPIQPLRLFVPNSYPNSSPVLLDKFPTEVSKEYEDLSVKAKSRFSISLRSLSQPMSLGEIARTWDVCARAAISEYAQQSGGGSFSSKYGTWENYLSAI
Length1360
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.03
Grand average of hydropathy-0.754
Instability index71.33
Isoelectric point9.48
Molecular weight149389.31
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19758
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.67|      28|      29|     825|     853|       1
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  329-  361 (37.99/ 7.12)	LRQQQqtpiiHQQQTPMQPQTMLPPQQQQQ.QQQ
  849-  879 (38.68/ 9.32)	QMQQQ...lmQKQQLLQQQQQQQQQQLHQQtKQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     722.95|      93|     122|     311|     431|       2
---------------------------------------------------------------------------
  138-  233 (82.64/15.94)	ANP.GQ........ARQQLLSQ..NiPNNI....aATgiqgsasltsalPPV.........................GG................LPSTTM..PN..V.VG..QNSNL....Q...NIQN....ISGvSQNS..................VGNPM...GQgvsNNI......FA........................................NT...QRQM..P.............G..................RQQQV
  236-  308 (88.20/17.61)	QQQ.QQ........QSQ.......N.SQHY.............................................LYQQ................QLQQQMMKQK.Y......QQGNIPNTN................IQ.....................SHLQ...PQ...QPH................................................HQ...QNLL.qSNQ..LQvsQpsiMQ..................PSAQL
  311-  431 (152.39/36.97)	LQQ.SQ........SAQTMLQQ..N.PQSVlrqqqQT............PIIhqqqtpmqpqtmlppqqqqqqqqLMGQ................QPNSTIMQPN.QL.IG..QQNNIPDMQQ...QQQR....LLG.QQNS..................LSNLQ...QQ...QQQ......LM........................................NQ...QNNL..PNQ..LQ..Q...LG..................PQSNI
  434-  515 (85.59/16.83)	LQQ.RH........QHQHQQQQlhV.PQS...................................................................GNSS.LQTN.QQsIHmlQQSKVP.LQQ...QNQQsaatLLP.TQGQ..................QSEPQ...PL...QQQ......LI........................................SQ...IQSQ..PGQ..LQ..Q............................
  519-  650 (59.72/ 9.03)	.QQhPN........SLQQDMQQ..R.LQA...............................................SGP..............lvQSQSMIDQQK.QL.LQ..PQRAIPEASStslDSTA....QTG.NANSgdwqedvyqkikamkeayLPELN...EM...YQK......VA........................................GKlqqHDSF..PQQpkSE..Q...LEklksfknmleriiaflqvSKSNI
  681-  774 (98.45/20.71)	LQQ.GQqlppphvqSVQ.QAQQ..S..QS......QI............S...........................QS................QPHEIQMNPQlQS.VN..FQGSVPMMQQ...SNVA....NM..QHNS..................LSSLSgvtNT...SQS......MI..............................................NSL.qPST..NM..D...SG...................QGNA
  775-  913 (66.43/11.05)	LNN.LQ........VAVGSLQQ..N.PVNT...............................................PQqvtinslsshngmnvlQPNLTPLQSN.SN.ML..QHQHLK..QQ...EQQM....LQT.Q........................LK...QQ...FQQrqmqqqLMqkqqllqqqqqqqqqqlhqqtkqqqnvqlqahqmsqlhqmND...VNDL..KMR...Q..Q...MG..................VKSGV
  914-  994 (89.54/18.02)	FQQ.TH........SAGQRAAY..H.YQQ...............................................LKS................GAPFPISSPQ.LL......QAASPQMLQ...HASP....QID.QQNM..................LTSLT...KS...GTP......LQ........................................SA...SSPFvvPSP..PT..P...LA..................P....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.53|      18|      45|    1104|    1121|       3
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 1113- 1130 (26.16/17.25)	GSRAAVGED.........LVAMTKCRL
 1131- 1157 (19.37/10.60)	QARTIATQDtnagtrkmkRYTSAIPLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.15|       9|      16|    1168|    1177|       5
---------------------------------------------------------------------------
 1168- 1177 (12.33/12.29)	SFKRlTGSEA
 1187- 1195 (16.82/10.73)	SIKR.PRSEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.42|      22|      47|    1249|    1270|       7
---------------------------------------------------------------------------
 1249- 1270 (39.29/21.86)	LSPNLKSHYASAQMSPIQPLRL
 1298- 1319 (36.13/19.45)	LSVKAKSRFSISLRSLSQPMSL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19758 with Med15 domain of Kingdom Viridiplantae
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