<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19748

Description Serine/threonine-protein kinase isoform 2
SequenceMAVVSRMPLTLQQINPITYHNFKNPRMMASRGEISEEPPVQVVEDKVYVAVGKEYSESKSTLTWALHNSGGRKICILHVHEPAQRIPFMGTKIQASRLEEQQVKAYRETEKQDMNKLLREYGMLCKQAGVHAELLHIEMESIEKGILELISQHSIRKLVMGAAADKHYSKKMLEPKSKKAIHVRLQAPISCHIWFICRGNLVHTREGRLEGVSMEVASLIQQASPKTEIGKSNQWRSRSTNQVQNDQLTLFTPSPQHRRVRSDVRGTEASTSSPDSSREGTPCSTERNFSEWDRISGWSPSLNSLFSPFSAGDMADDSALASAARAEDGLESRAMHHLKDDCQLTSPSSVLERVMKDELYDKLKQAMEEVENSRREAFEESVRRRKAEKEAIDAFRRAKTAESLYAEEMRQRKETEEALAKGKEELENMKQKVDEVMEELGISLEQNSSLESQIAHTEKTIQELEQKMFSAVELMQKYKTERDELQVEHDNALTVSEELRKKYSEKSSNSLMPQIFSEFSFSEIERATNNFDPALKIGEGGYGIIYKCLLRNTQVAIKMLHSHSLQGPLEFQQEVNILSKLRHPNLVTLVGACPETWTLVYEYLPNGSLEDRLSCKDNTPPLSWQTRLRIAVELCSVLIFLHNSTPHNIVVHGDLKPANILLDENYVCKLSDFGICRAISQNELSSNNTTLCCRTDPKGTFAYMDPEFHATGELTRKSDTYSFGIILLRLLTGRSVFGLPKEVQCALDKGTLKNLLDPTAGDWPFVQAKQLAHLAMRCCEMNRRRRPDLASDVWRMLEPMSVLCGASSFRLSSDERCQIPPYFICPIFQKIMQDPHVAADGFSYELEAMRRWLDSGHNTSPKTNLKLTHCNLVPNHTLRSAIQEWLHQP
Length889
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.06
Grand average of hydropathy-0.526
Instability index52.07
Isoelectric point6.52
Molecular weight101070.06
Publications
PubMed=29661190

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP19748
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     131.52|      36|      49|     671|     706|       1
---------------------------------------------------------------------------
  633-  664 (19.25/ 9.32)	.................ELCSvliflHNSTphnIVVHGDLKPAN.ILLDE
  671-  706 (67.72/54.44)	SD...FGI..CRAISQNELSS.....NNTT...LCCRTDPKGTF.AYMDP
  718-  758 (44.55/32.86)	SDtysFGIilLRLLTGRSVFG.....LPKE...VQCALD.KGTLkNLLDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.60|      15|      19|     252|     268|       2
---------------------------------------------------------------------------
  232-  247 (22.91/ 8.07)	SNQWRsRSTNQVQNDQ
  254-  268 (26.69/18.95)	SPQHR.RVRSDVRGTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     192.76|      64|     286|     492|     597|       3
---------------------------------------------------------------------------
  517-  597 (91.06/138.17)	SEFSFSEIERAtnNFDPalkigeggYGI..IYKCLLRNTQVAIKMLhSHSLQGPLEFQQE.....vnilsKLRHPNLV...TLVGACPEtW
  807-  885 (101.71/58.51)	SSFRLSSDERC..QIPP........YFIcpIFQKIMQDPHVAADGF.SYELEAMRRWLDSghntspktnlKLTHCNLVpnhTLRSAIQE.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.04|      12|      19|     364|     375|       6
---------------------------------------------------------------------------
  364-  375 (19.85/15.42)	KQAMEEVENSRR
  386-  397 (19.19/14.62)	KAEKEAIDAFRR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP19748 with Med32 domain of Kingdom Viridiplantae

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