<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19743

Description Mediator of RNA polymerase II transcription subunit 37e
SequenceMAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPINTVFDAKRLIGRRFTDATVQSDMKMWPFKVIAGPGDKPMIVVSYKGEDKQFAAEEISSMVLIKMREIAEAYLGSTVKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGNPRALRRLRTSCERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKSSVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERTRTRDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKDEIEKMVQEAEKYKSEDEEHKKKVEAKNALENYAYNMRNTIKDEKIGEKLQPADKKKIEDAIEQAIQWLDSNQLAEADEFEDKMKELESICNPIIAKMYQGAGGDMGAGAMDDDSPPPSGSAAGPKIEEVD
Length649
PositionUnknown
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.06
Grand average of hydropathy-0.422
Instability index35.48
Isoelectric point5.10
Molecular weight71297.04
Publications
PubMed=29661190

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
ATPase activity	GO:0016887	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP19743
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.11|      45|     189|     170|     218|       1
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  170-  218 (62.52/58.20)	GLNVMRIINePTaAAIAYGLDKKATSV.GEKNVLIFDLggGTFDVSLLTI
  362-  407 (71.59/48.70)	GKELCKSIN.PD.EAVAYGAAVQAAILsGEGNEKVQDL..LLLDVTPLSL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.00|      18|      21|      38|      55|       2
---------------------------------------------------------------------------
   16-   33 (19.07/10.36)	....TTYSCVGVWQHDRveIIA
   38-   55 (32.65/22.73)	NR..TTPSYVAFTDTER..LIG
   60-   78 (24.28/15.11)	NQvaMNPINTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.50|      27|     484|     114|     140|       3
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  114-  140 (44.44/34.37)	EDKQFAAEEISSMVLIKMREIAEAYLG
  599-  625 (49.06/38.77)	EDKMKELESICNPIIAKMYQGAGGDMG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.83|      25|      42|     511|     535|       4
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  511-  535 (41.12/28.48)	NDKGRLSKDEIEKMVQEAEKYKSED
  554-  578 (41.71/29.00)	NMRNTIKDEKIGEKLQPADKKKIED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.19|      34|      44|     427|     461|       6
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  427-  461 (53.16/43.25)	PTKKEQVFSTYSDNQPGVLiQVYEGERTRTRDNNL
  474-  507 (57.02/41.38)	PRGVPQITVCFDIDANGIL.NVSAEDKTTGQKNKI
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP19743 with Med37 domain of Kingdom Viridiplantae

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