<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19743

Description Mediator of RNA polymerase II transcription subunit 37e
SequenceMAGKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPINTVFDAKRLIGRRFTDATVQSDMKMWPFKVIAGPGDKPMIVVSYKGEDKQFAAEEISSMVLIKMREIAEAYLGSTVKNAVVTVPAYFNDSQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKATSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVQEFKRKNKKDISGNPRALRRLRTSCERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKSSVHDVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGNEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERTRTRDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKDEIEKMVQEAEKYKSEDEEHKKKVEAKNALENYAYNMRNTIKDEKIGEKLQPADKKKIEDAIEQAIQWLDSNQLAEADEFEDKMKELESICNPIIAKMYQGAGGDMGAGAMDDDSPPPSGSAAGPKIEEVD
Length649
PositionUnknown
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.06
Grand average of hydropathy-0.422
Instability index35.48
Isoelectric point5.10
Molecular weight71297.04
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
ATPase activity	GO:0016887	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19743
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.11|      45|     189|     170|     218|       1
---------------------------------------------------------------------------
  170-  218 (62.52/58.20)	GLNVMRIINePTaAAIAYGLDKKATSV.GEKNVLIFDLggGTFDVSLLTI
  362-  407 (71.59/48.70)	GKELCKSIN.PD.EAVAYGAAVQAAILsGEGNEKVQDL..LLLDVTPLSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.00|      18|      21|      38|      55|       2
---------------------------------------------------------------------------
   16-   33 (19.07/10.36)	....TTYSCVGVWQHDRveIIA
   38-   55 (32.65/22.73)	NR..TTPSYVAFTDTER..LIG
   60-   78 (24.28/15.11)	NQvaMNPINTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.50|      27|     484|     114|     140|       3
---------------------------------------------------------------------------
  114-  140 (44.44/34.37)	EDKQFAAEEISSMVLIKMREIAEAYLG
  599-  625 (49.06/38.77)	EDKMKELESICNPIIAKMYQGAGGDMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.83|      25|      42|     511|     535|       4
---------------------------------------------------------------------------
  511-  535 (41.12/28.48)	NDKGRLSKDEIEKMVQEAEKYKSED
  554-  578 (41.71/29.00)	NMRNTIKDEKIGEKLQPADKKKIED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.19|      34|      44|     427|     461|       6
---------------------------------------------------------------------------
  427-  461 (53.16/43.25)	PTKKEQVFSTYSDNQPGVLiQVYEGERTRTRDNNL
  474-  507 (57.02/41.38)	PRGVPQITVCFDIDANGIL.NVSAEDKTTGQKNKI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19743 with Med37 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GAGGDMGAGAMDDDSPPPSGSAAGPKIEEVD
2) KDEIEKMVQEAEKYKSEDEEHKKKVEAKNA
619
518
649
547










Molecular Recognition Features






MoRF SequenceStartStop




NANANA