<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19737

Description Serine/threonine-protein kinase
SequenceMAVVSPMSVVPPEINPIRYPDIEINGTMASRSEIVEESSPVRVVEDKIYVAVGKDLKESKLTLSWALHKSGGRKLCILYVLEPAQRIPLMGTKFLPSQLEEHQVRAYRETERQDMNKLLCDYRMICDRAGVRVDVLHIEMDSIEKGIVELISQHGIRKLIMGAAADKYYSKKMMEPKSKKAIYVRLQAPMFCHIWFLCKGNLVHTREGRLEGGSTEVASVTLRASPNTGSGQSGYLRSQSVTEGQKNQLKLISAVPDHRRGWSDIHGMNVSTFSPDSSRGITPRSISNAEVSFSDWDEISRRSPSLTSRFSSCSSRDMDDYSALNSAARAEAQLESQELHHSKEDHPYSSPPSVLEGGMNDELYDQLEQAMAEAENSRREAFEESTRRRKAEKDAIDAVRRARTSETLYVEESRQRKEIEEDLARGKEELEKIKQQVDEVMEELHLALEQKSSLESQIASTNQMVQELEDKMFSAVDLLQKYKKERDELQVERDNVLKVAEELRKKQTEEASQSVMPQFFSEFSFSEIEAATTSFDPSLKIGEGGYGSIYRGFLRHTQVAIKMLHSHSLQGPSEFQQEVNILSKLRHPNLVTLVGACPEAWILVYEYLPNGSLEDRLSCRGNTPPLSWQTRIRIAAELCSALVFLHSCNPHSVVHGDLKPANILLDANFVSKLSDFGISRVITQNELSSNNTTLCCRTEPKGTFAYMDPEFLSTGELTPMSDVYSFGIILLRLLTGRPALGITKEVQYALDKGNLKDLLDPTAGDWPFVQAKQLAHLAIRCCEMSRKSRPDLGSDVLRVLEPMRVSCGASSFWMSSEEHCQIPSYFICPIFQETMQDPHIASDGFTYELEALKGWIESGHDTSPMTNLKLPHCNLVPNRALRSAIQEWLQQ
Length891
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.07
Grand average of hydropathy-0.439
Instability index55.74
Isoelectric point5.70
Molecular weight100426.91
Publications
PubMed=29661190

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19737
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.97|      43|      50|     428|     477|       1
---------------------------------------------------------------------------
  428-  477 (58.05/43.05)	EELEKIKQQVDEVMEELhlaleqKSSlESQIASTNQMVQELEDKMFSAVD
  487-  529 (69.91/36.45)	DELQVERDNVLKVAEEL......RKK.QTEEASQSVMPQFFSEFSFSEIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     178.28|      45|      46|     262|     306|       2
---------------------------------------------------------------------------
  225-  273 (62.81/39.33)	SPNTGSGQSGylRSQSVTEGQKNQLKLIS.AVPDHrrgWSDI...HGMNVSTF
  274-  321 (69.98/44.75)	SPDSSRGITP..RSISNAEVSFSDWDEISRRSPSLtsrFSSC...SSRDMDDY
  322-  360 (45.48/26.22)	SALNSAARAE..AQLESQELHHSKEDHPYSSPPS........vleGGMN....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.46|      43|      50|     637|     683|       3
---------------------------------------------------------------------------
  637-  683 (62.41/54.83)	ELCSALVFLhSC..NPHSvVHGDLKPAniLLDANFVSKLSD...FGI..SRVIT
  686-  735 (64.04/40.34)	ELSSNNTTL.CCrtEPKG.TFAYMDPE..FLSTGELTPMSDvysFGIilLRLLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.96|      47|      51|     790|     836|       4
---------------------------------------------------------------------------
  790-  836 (88.69/53.08)	PDLGSDVLRV.LEPMR..VSCGASSFWMSSEE..HCQ.IPSYFICPIFQETMQ
  838-  890 (66.27/37.96)	PHIASDGFTYeLEALKgwIESGHDTSPMTNLKlpHCNlVPNRALRSAIQEWLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.52|      40|     341|      19|      86|       5
---------------------------------------------------------------------------
   19-   58 (66.86/74.56)	YPDIE..INGTMASRSEIVEESSPVRVVE.............DKIYVAVGKDLKE
  364-  418 (52.66/18.50)	YDQLEqaMAEAENSRREAFEESTRRRKAEkdaidavrrartsETLYVEESRQRKE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19737 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DYSALNSAARAEAQLESQELHHSKEDHPYSSPPSVLEGGMNDELYDQLEQAMAEAENSRREAFEESTRRRKAEKDAIDA
2) RARTSETLYVEESRQRKEIEEDLARGKEELEK
320
401
398
432










Molecular Recognition Features






MoRF SequenceStartStop




NANANA