<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19730

Description Mediator of RNA polymerase II transcription subunit 15a like
SequenceMDYKLVESDSNFDVNDWLAESKSEPEVGNSGIEDARIQDSTLNSCNLSQLENSSVKLEEKFCQNEASKPVSMSRTCQRVIPMESLYHHSSSTASSCSAMTQSIKTEPSGQGFSLQSMSAYSHEPAGNLVGQTMQSNIFANSQSQSSQQAVLQHQHQQLQQQQLLNQNVQRPHIQSSSMQSKIQYYHQRQQEQHNLSLPTEVGSSQQTMSTAVQDQRRVGQHPNATILQQNHHFGMQEKHQQMPPYQQNISTMFKQSSGLQNNVTGLQQPQQQKFTRARSDVLNMQPQQYALHILQQPEVTAPQKNFQQTSQPIQLDKLLGLHNQRNSLQESTQKRHQTSAALLPQTGIIDHPKHLEQSQRVLPEGSSASVGSTSQTRLDHWRGQAYQQLESAREMFLTEAIGLYNMVRKSCLQSPSPEIPAKYDRNRIFIGKSIRFLKMSRADIDHQCSKDKFYYYLNMITDYFTLIRSRNLVSAQQHGQQQPPGSQSENPQPQQQINTKLQFHSVNRGLTGAPAGSPQLSTHQAIPSSQANKTNFIHKGSSSGSEPNNAWSPLQHGSPHQLTMRRLQQTNTINSLHDSSLIGMEQRNLVDPLLHNGVRSLCPNMLNTLQQTNFSHMTTVNELEPTTNPCPSSSTTPFLNLKQQPIHQMMQTQTLKQSLQQPSIEKKKKQMSKQKMHEINEPKPGQVVSFSSGMLKEHHSVSQHMQYSPQSLLPSIPHLNSGSPQTSHHSSQQPNQIFLLSHLSKAGTHLQCAASQFTSPSPSTPLTPSSLLVDLEKNSTGISPLSAAKNTEHTQTPEILASSVLEEFTGPEDNQETNTMEPSLKCLLELVETISPRALSSSVQDIGAVIDMTDRISVITASESRVAIGDYLATDTSHRLQGRTFSLDCGSTSSKLKKRSRSIRTIALDLLSSPFNENDGLEWPSRQTIDMDSTATSRIKRPRTELNCALLEEIKETNQKLVETLIDVVLNSTECAVKAGFGEGMIVRCSYSAIGLGGNFNQHYASARMELPILAVKLLVPADYPKSSPIFLNTPLTSWSEVEATENLSEKAKLRFSLSLRKLSQPMSLGEMARTWDVCARTVLSDFAQSMGGGSFSSTYGTWENCITAA
Length1110
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.05
Grand average of hydropathy-0.648
Instability index65.24
Isoelectric point7.67
Molecular weight123511.97
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19730
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.62|      11|      16|     106|     116|       1
---------------------------------------------------------------------------
  106-  116 (21.42/10.64)	EPSGQ..GFSLQS
  123-  135 (17.20/ 7.09)	EPAGNlvGQTMQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     261.43|      51|      51|     662|     712|       2
---------------------------------------------------------------------------
  477-  519 (38.14/13.86)	........QHGQQQ..PpgsQS....ENPQPQQQINtKLQFHSVNRGltgAPA.....G....SPQ
  520-  553 (48.88/20.17)	LSTHQAI..................PSSQANK..TN.FIHKGSSSGS...EPNNAWSP........
  603-  634 (34.25/11.57)	.........................PNMLNTLQQTN.FSHMTTVNEL...EPTTNPCPS....SS.
  641-  694 (73.90/34.87)	LKQ.QPIHQMMQTQtlK...QSLqqPSIEKKKKQMS.KQKMHEINEP...KPGQVVSFS....SGM
  695-  747 (66.26/30.39)	LKEHHSVSQHMQYS..P...QSL.lPSIPHLNSG.S.PQTSHHSSQ....QPNQIFLLShlskAG.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     304.13|      56|      56|     232|     287|       3
---------------------------------------------------------------------------
  147-  197 (46.87/15.81)	...QQA.........VLQHQHQQLQQQQllNQ..........NVQRP.....HIqssSMQSKiqyYH.QRQQEQHNLSL
  198-  251 (83.42/33.35)	PTEVGS.........SQQTMSTAVQ..D..QRRVGQHPNATILQQNH.....HF...GMQEK...HQ.QMPPYQQNIST
  252-  305 (70.73/27.26)	MFKQSS.........GLQNNVTGLQQPQ..QQKFTRARSDVLNMQPQ.....QY...ALHIL...QQpEVTAPQKN...
  306-  370 (54.05/19.26)	.FQQTSqpiqldkllGLHNQRNSLQEST..QKRHQTSAA....LLPQtgiidHP...KHLEQ...SQ.RVLPEGSSASV
  371-  415 (49.05/16.86)	....GS.........TSQTRLDHWRGQA..YQQLESAREMFLTEAIG.....LY...NMVRK...SC.LQSP.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.16|      20|      21|     832|     851|       4
---------------------------------------------------------------------------
  793-  829 (18.75/ 7.04)	HTQTPEILASSVleeftgpednqetntmePSLKCLLE
  832-  851 (31.41/16.92)	ETISPRALSSSV.................QDIGAVID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.87|      15|      22|     888|     909|       5
---------------------------------------------------------------------------
  893-  909 (20.06/13.77)	SSKLKKRSRsiRTIALD
  918-  932 (28.80/11.15)	NDGLEWPSR..QTIDMD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19730 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) CSAMTQSIKTEPSGQGFSLQSMSAYSHEPAGNLVGQTMQSNIFANSQSQSSQQAVLQHQHQQLQQQQLLNQNVQRPHIQSSSMQSKIQYYHQRQQEQHNLSLPTEVGSSQQTMSTAVQDQRRVGQHPNATILQQNHHFGMQEKHQQMPPYQQNISTMFKQSSGLQNNVTGLQQPQQQKFTRARSDVL
2) HHSVSQHMQYSPQSLLPSIPHLNSGSPQTSHHSSQQPNQIFLL
3) ISPLSAAKNTEHTQTPEILASSVLEEFTGPEDNQETNTMEP
4) LVSAQQHGQQQPPGSQSENPQPQQQINTKLQFHSVNRGLTGAPAGSPQLSTHQAIPSSQANKTNFIHKGSSSGSEPNNAWSPLQHGSPHQLTMRRLQQTNTINSLHDSSLIGMEQRNLV
5) NMLNTLQQTNFSHMTTVNELEPTTNPCPSSSTTPFLNLKQQPIHQMMQTQTLKQSLQQPSIEKKKKQMSKQKMHEINEPKPGQVVSFSSGMLK
6) QPQQYALHILQQPEVTAPQKNFQQTSQPIQLDKLLGLHNQRNSLQESTQKRHQTSAALLPQTGIID
96
698
782
472
604
285
282
740
822
590
696
350










Molecular Recognition Features






MoRF SequenceStartStop




1) KIQYY
181
185