<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19728

Description Mediator of RNA polymerase II transcription subunit 15a like
SequenceMDTNNWRPAPGGAGEPTMDGDWRAQLLPDSRQRIVNKIMDTLKRHLPFSGQEGLQELKKIAVRFEEKIYTCATSQPDYLRKISLKMMTMENKSQNTMANSLPSNSASNSKNPPDTAGSLGMPSQITNQGQSLPIPMAANQGQARQQLLSQNISNNIAATGVQGSASLTLPAVGGLPPTTMSNVVGQNSNLQNIQNISGVSQNSVGNPMGQGVSNNIFSNTQRQMPGRQQQVATQQQQQQSQNSQHYLYQQQLQQQMMKQKYQQGNIPNTNIQSHLQPQQQQQQQNLLQSNQLQSSQQSIMQPSAQLSGLQQSQSAQPMLQPNPQSVLRQQQQQQTPIIHQQQTPMQPQTMLPPQQQQQQQLMGQQPNSTIMQQNQLIGQQNNIPDMQQQQQRLLGQQNSLSNLQQQQLMSQQNNLPNQQQQLGPQSNIAALQQRQQQLLVPQSGNSSMQTNQQSIHMLQQSKVPLQQQNQQGAATLLPTQGQQSEPQPPQQQLISQIQSQPGQLQQHGFQQHPNSLQRDMQQRLQASGPLIQSQIMIDQQKQLLQSQRSIPEASSTSVDSTAQTGNANSGDWQEDVYQKIKAMKEAYLPELNEMYQKISGKLQQHDSFPQQPKSEQLEKLNMFKIMLERIVTFLQVSKSNILPGFKDKMGSYEKQIINFLNSNRPRKPGPTLQQGQQLPPPHVQSVQQAQQSQSQISQSQPHENQMNPQLQSSNFQGSVPMMQQSNVGNMQHNSLSSLSGVANTSQSMINSLQPSTNMDSGQGNALNNLQVAVGSLQQNPVNTPQQVNINSLSSHNGMNVLQPNLTPLQSNSNMLQHQHLKQQEQQMLQTQLKQQFQQRHMQQQLMQKQQLLQQQQQQQQQQQQLHQQTKQQQQNAQLQAHQMSQLHQMNDVNDLKMRQQMGVKSGVFQQTHSAGQRSAYHHQQSKSGAPFPTSSPQLLQAASPQMLQHASPQIDQQNMLTSLTKSGTPLQSASSPFVVPSPSTPLAPSPMPGESEKVNSGVPTLSNAGNIGHPQTAGAVTPVQSLAIGTPGISASPLLAEFTSPDGNHGNASTVVSGKSSVTEQPLERLIKVVKSMSPKSLSASVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNIATQDTNIGTRKMRRYTSAIPLNVASSAGSGNDSFKHLTGSEASDLESTATSSIKRPRIEANHALLEEIRGINLRLIDTVVSISEEDVDPTAAAAITTEGGEGTVVQCSFSAVALSPNLKSHYASTQMSSIQPLRLFVPNSYPNSSPALLDKFPTEVSKEYEDLSVKAKSRFSISLRSLSQPMSLGEIARTWDVCARAVISEYAQQSGGGSFSSKYGTWEDCLSAT
Length1354
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.03
Grand average of hydropathy-0.763
Instability index74.00
Isoelectric point9.33
Molecular weight148647.39
Publications
PubMed=29661190

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19728
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     137.20|      29|      29|     356|     384|       1
---------------------------------------------------------------------------
  352-  383 (55.59/14.82)	PpqqQQQ..QQLMGQQPNSTIMQQNQLIGQQNNI
  384-  415 (45.12/10.38)	PdmqQQQ..QRLLGQQNSLSNLQQQQLMSQQNNL
  828-  858 (36.49/ 6.72)	L...QTQlkQQFQQRHMQQQLMQKQQLLQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     237.51|      37|      37|     417|     453|       2
---------------------------------------------------------------------------
  233-  280 (41.57/ 8.51)	TQQQQQQSQ..NSQHYLyqQQL..QQQMMKQkyQQGNipntniqSHLQPQQQ
  281-  314 (45.60/10.26)	.QQQQNLLQ..SN..QL..QSS..QQSIMQP..SAQL.......SGLQQSQS
  322-  350 (44.21/ 9.66)	NPQSVL..........R..QQQ..QQQTPII..HQQQ.......TPMQPQTM
  417-  453 (66.39/19.26)	NQQQQLGPQ..SNIAAL..QQR..QQQLLVP..QSGN.......SSMQTNQQ
  488-  521 (39.75/ 7.73)	PPQQQLISQiqSQPGQL..QQHgfQQH...P..N...........SLQRDMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.56|      36|      36|     923|     958|       3
---------------------------------------------------------------------------
  923-  955 (52.30/20.41)	......QQSKSG.......APFPTSSP.....QLLQAASPQMLQHASPQID
  956-  999 (44.82/16.44)	QQNmltSLTKSGtplqsasSPFVVPSP.....STPLAPSP..MPGESEKVN
 1049- 1089 (35.44/11.48)	HGN..aSTVVSG.......KSSVTEQPlerliKVVKSMSPKSLSASVSDI.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     133.52|      17|      17|     691|     707|       4
---------------------------------------------------------------------------
  691-  707 (34.24/12.46)	QSQSQISQSQPHENQMN
  711-  726 (24.46/ 6.31)	QS.SNFQGSVPMMQQSN
  784-  799 (25.36/ 6.88)	PQQVNINSLSSH.NGMN
  809-  824 (25.09/ 6.71)	QSNSNMLQHQ.HLKQQE
  871-  884 (24.37/ 6.26)	Q.QQQNAQLQAH..QMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     121.36|      34|      36|     128|     161|       5
---------------------------------------------------------------------------
  123-  153 (47.83/15.99)	SQIT....nQGQ.SLPIP.........MAANQGQ..ARQQLLSQNIS
  154-  197 (41.27/12.82)	NNIAATGV.QGSaSLTLPavgglppttMSNVVGQ..NSNLQNIQNIS
  202-  229 (32.26/ 8.46)	NSVGNPMG.QGV.SNNI..........FSNTQRQmpGRQQ.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     256.04|      80|     558|      20|     104|       7
---------------------------------------------------------------------------
   20-  104 (129.75/86.22)	GDWRAQL...........LPDSRQrIVNKIMDTLKRHLPFSGQ...EGLQELKKIAVRFEEKIYTCATSQPDYLRKISLKMMTMENKsqntMANSLPSN
  570-  663 (126.29/72.08)	GDWQEDVyqkikamkeayLPELNE.MYQKISGKLQQHDSFPQQpksEQLEKLNMFKIMLERIVTFLQVSKSNILPGFKDKMGSYEKQ....IINFLNSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     252.30|      83|     115|    1092|    1180|       8
---------------------------------------------------------------------------
 1092- 1180 (123.42/87.41)	VVSM....IDRIAGSA....PGNGSRAAVGEDLVAMTKcRLQARNIATQDTNIgtRKMRRYtsaIPLNVASSAGSGNDSFKHLTGSEASDLESTATS
 1208- 1298 (128.88/74.18)	VVSIseedVDPTAAAAitteGGEGTVVQCSFSAVALSP.NLKSHYASTQMSSI..QPLRLF...VPNSYPNSSPALLDKFPTEVSKEYEDLSVKAKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.79|      14|      92|     674|     688|      10
---------------------------------------------------------------------------
  522-  535 (20.79/ 7.17)	QRLQASGPLIQS.QI
  674-  688 (24.00/13.98)	QGQQLPPPHVQSvQQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19728 with Med15 domain of Kingdom Viridiplantae
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