<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19717

Description Mediator of RNA polymerase II transcription subunit 19a like
SequenceMQLDQLIQDMSYSRGTNARIQPFDLNVLSEAFQLRDTTQIDLPPAEKGVPTVAGKSKSKSKDKERKHKKHKDKDREKDKDDKKHKHRHKDRSKDKDKEKKKDKSGHQDSGAENLKKHHEKKRKHDGDENLTDIHSHKKSKHKSTKTEETGAIKVAG
Length156
PositionHead
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.02
Grand average of hydropathy-1.829
Instability index34.61
Isoelectric point9.75
Molecular weight18013.98
Publications
PubMed=29661190

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP19717
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.58|      15|      15|      69|      83|       1
---------------------------------------------------------------------------
   69-   83 (26.96/ 8.03)	KHKDKDREKDKDDKK
   85-   99 (26.63/ 7.85)	KHRHKDRSKDKDKEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.97|      15|      15|     110|     124|       2
---------------------------------------------------------------------------
  110-  124 (29.26/12.44)	GAENLKK.HHEKKRKH
  126-  141 (24.71/ 9.54)	GDENLTDiHSHKKSKH
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP19717 with Med19 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MQLDQLIQDMSYSRGTNARIQPFDLNVLSEAFQLRDTTQIDLPPAEKGVPTVAGKSKSKSKDKERKHKKHKDKDREKDKDDKKHKHRHKDRSKDKDKEKKKDKSGHQDSGAENLKKHHEKKRKHDGDENLTDIHSHKKSKHKSTKTEETGAIKVAG
1
156

Molecular Recognition Features

MoRF SequenceStartStop
1) ENLTDIHSHKK
2) RIQPFDL
3) TVAGKSKSKSKDKERKHKKHKDKDREKDKDDKKHKHRHKDRSKDKDKEKKKDKSGHQDSGAENLKKHHEKKRKH
128
19
51
138
25
124