<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19710

Description Mediator of RNA polymerase II transcription subunit 33A like
SequenceMVVVSVMSSGLWDSVLELTNVAQEKGSDPLLWALQVSSNLNCAGVVLPCPELANLLVSHICWANNVPIAWKFLEKALAFKIAPPLLVLALLSNRVIPNRSLRPAAYRLYMDLLKRHALTLKSHTDGPNFHKVMNSVDNVLHLSQTFGLQASEPGVIVVEFIFSIVCQLVDASLDDEGLLELTPEKKSKWVTKSQDMEIDSYDNYDEKRIEHQERLQNLNTVMAVELIGNFLQNKVTSRILYLARQNMPLHWGSFLQQIQLLVANSSAVRNSKVTTAEALQQLATGTCKILSWECKMISPQKFHEVMASGSLASSAGLCHGASRSALWLPLDLVLEDFMDGSQVNATSAVEIITGLLKALQAFNGTTWHESFLGLWMAALRLIQREKDPIEGPVPRLDTRLCMLLTISSLVIADLIEEEESAATDEMECTDGIHGKEKEVPGMRRGDLVSSLQSLGDCKGLLAPPQSVISAANQAAAKAMMFISGINVGTAYFECVSMKDMPLNCSGNMHHLIVEACIARNLLDTSAYFWPGYVNGLINQIPQTLPVQVPSWSSFMKGAPLTPTMKNALVSAPASSLAELEKVFEIAVKGSDDEKIAAAAILCGASLIRGWNIQEHIVYFISRLLCPPVPADYSGSDSHLISYGPMLNVLLVGIAPVDCVQIFSLHGLVPQLACSLMPICEVFGSCVPNFSWTLPTGAEVSAHAVFSNAFALLLKLWRFNHPPLEHGVGDVPPVGSQLTPEYLLAVRNSHLVSSGNIHSDRCRRRLSSVARSSSPKPIFLDSFPKLKVWYRQHLACIASTLTGLVHGTPVHQIVDGLLNMMFRKINRASQSVTTVTSGSSSSSGPGNEDTFVRPKLPAWDVLEAVPFVVDAALTACAHGRLSPRELCTGLKDLADFLPASLATIVSYFSAEVTRGIWKPAFMNGTDWPSPAANLSNVEGQIKKILAATGVDVPSLIAGGRSPATLPLPLAAFVSLTITYKLDKASQRFLNLAGPALETLAAGCPWPCMPIVASLWTQKAKRWSDYLVFSASQTVFLHNNDAVVQLLKSCFTATLGLNVTPISSNGGVGALLGHGFGSHFCGGISPVAPGILYLRVYRSIRDMMFIREEIISLLMQCVREIACSAVSKDRMEKLKKVKNGIRYGQVSLATAMTQVKLAASLGASLVWLSGGSALVQSLIKETLPSWFISVHRSEQEESSGGVVAMLGGYALAYFATLCGAFSWGVDSSSSASRRRPRILGTHMEFLASALDGKVSLGCNWATWCAYVSGFLSLMVACTPTWVLEVDMEVLKRLSKGLRQWNEEKLAFDLLGVGGVGTMGVAAELIIESET
Length1328
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.07
Grand average of hydropathy0.225
Instability index43.89
Isoelectric point6.60
Molecular weight143873.29
Publications
PubMed=29661190

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP19710
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     307.36|      98|     104|     856|     958|       1
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  856-  958 (160.21/89.00)	PAWDVLEAVPFVvdaALTACAH.GRLSPREL.CTG..LKDLADFLP.ASLATIVSYFSAEVTRgiWKPAFMNGTDWPSPAANLSNVEGQIKKILAAT.GVDVPSLIAGG
  961- 1064 (147.15/71.97)	PATLPLPLAAFV...SLTITYKlDKASQRFLnLAGpaLETLAAGCPwPCMPIVASLWTQKAKR..WSDYLVFSASQTVFLHNNDAVVQLLKSCFTATlGLNVTPISSNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     210.00|      58|     166|     460|     526|       2
---------------------------------------------------------------------------
  469-  526 (103.33/74.06)	SAANQAAAKAMM....FISGINV..GTAYFECV...SM.KDM.P.LNCSGNMHHLIVEACIARNL...LDTSA
  590-  650 (69.09/34.22)	SDDEKIAAAAILcgasLIRGWNIqeHIVYFISR...LLcPPV.P.ADYSGSDSHLISYGPMLNVL...L....
  652-  697 (37.58/15.39)	.........................GIAPVDCVqifSL.HGLvPqLACSLMPICEVFGSCVP.NFswtLPTGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.76|      16|      22|     243|     258|       3
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  243-  258 (31.03/23.37)	ARQNMPLHWGSFLQQI
  267-  282 (23.73/15.80)	AVRNSKVTTAEALQQL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.86|      30|      93|    1158|    1188|       4
---------------------------------------------------------------------------
 1158- 1188 (47.43/26.33)	SLGAS.LVWLSGGSALVqSLIKETLPSWFISV
 1253- 1283 (53.43/26.20)	SLGCNwATWCAYVSGFL.SLMVACTPTWVLEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.28|      23|     176|     127|     151|       5
---------------------------------------------------------------------------
  127-  151 (38.02/31.94)	P.NFHKVMNSvdNVLHLSQTFGLQAS
  299-  322 (38.26/24.94)	PqKFHEVMAS..GSLASSAGLCHGAS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.97|      18|     133|    1065|    1083|       7
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 1065- 1083 (32.79/24.47)	GVGALLGhGFG.SHF...CGGIS
 1199- 1220 (27.18/14.39)	GVVAMLG.GYAlAYFatlCGAFS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.52|      27|      67|     759|     785|       8
---------------------------------------------------------------------------
  759-  785 (49.76/28.56)	DRCRRRLSSV.....ARSSSPKPIFLDSF..PKL
  822-  855 (37.76/19.97)	RKINRASQSVttvtsGSSSSSGPGNEDTFvrPKL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.14|      25|     155|    1129|    1153|      11
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 1129- 1153 (41.99/29.08)	MEKLKKVKNGIR.YGQVSLATAMTQV
 1285- 1310 (38.16/25.72)	MEVLKRLSKGLRqWNEEKLAFDLLGV
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP19710 with Med33 domain of Kingdom Viridiplantae

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