<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19706

Description Serine/threonine-protein kinase
SequenceMELLSPTHPPLPMADHFSGFSPPTGFRRGFDRTSVTATSQPPEIVEEGGDRVHVAVGKSVDKAIALLRWSFEQFGNREICILHVHQPSPLIPTLLGKLPASQASTEVVSAFRRDEKERTRKLLSNYLSICTQSKVRASVTVTEASHVQKGIVDLVNEHGIRKLVMGATPENCMKVKTSSSKASYAAKNAPQFCEIWFVYKGKHVWTREAFESPSFVGSISQSEIATADNLREQCSQSELVFDPECTQPSSSRSIPCQGESVPIEAVLPPSLPCYINRFDPQCYHNFSSLTNTTSSSGYTSSADQRASSDSATKDDDEESLHDLLTEARIEAEASRDESFQEFLECKKLEAIGKFKALESARAHEIKLREEAEDALKMTIQEQETLLEEREEVTRELQRALRNIALLDSRAQEANHRREEMAGELKHIQASIAALQHEKQKIQQQRIESRCWLDRWRSRGQAAGATHNGVIGFSEDSLELAEFSLADLQIATCDFSESFKIGQSGYGSVYKGEMMDRTVAIKKLHPHNMQRQSEFLQEVQVLGKLQHPHLVTLIGTCPEAWSLVYEYLPNGSLQDRLSRRSNSCSLTWKIRARIIAEVSSALLFLHSCKPEKIVHGNLKPENIVFDSEVSCKICDFGIRKLMPEETLRCPSFRWGTELKGSFSYTDPEFSRTRSLTPKSDIYSLGLIILQLLTGRDPVGLASEVRKAVSCGKLSSILDSSAGEWPNFVAKQLMDLGLKCCELNSRDRPELTPSLVRELEQLYTLEERPAPSFFLCPILQEIMHDPQVAADGFTYEGDALCTWLENGSETSPMTNLKLDHLHLTPNHALKHAIRDWFLKS
Length838
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.07
Grand average of hydropathy-0.408
Instability index54.62
Isoelectric point5.87
Molecular weight93959.37
Publications
PubMed=29661190

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP19706
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.01|      14|      18|      22|      35|       1
---------------------------------------------------------------------------
   22-   35 (27.48/16.58)	PPTGFRRGFDRTSV
   41-   54 (26.52/15.76)	PPEIVEEGGDRVHV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.57|      27|     118|     479|     534|       2
---------------------------------------------------------------------------
  497-  526 (46.01/77.08)	SFKIGQSGYGSV.YKGEMMDRTvaiKKLHPH
  650-  677 (46.56/15.09)	SFRWGTELKGSFsYTDPEFSRT...RSLTPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.22|      22|     476|     122|     174|       3
---------------------------------------------------------------------------
  145-  174 (27.59/78.92)	SHVQKGIVDLvnehGIRKLvMgatPENCMK
  626-  647 (42.64/18.17)	SEVSCKICDF....GIRKL.M...PEETLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     181.64|      46|      46|     368|     413|       6
---------------------------------------------------------------------------
  313-  365 (51.16/28.71)	KDDDEESLHDLLTEA.RIEAEaSRDESFQEFLecKKLEAIgkfkALES...ARAHEI
  368-  413 (72.50/43.53)	REEAEDALKMTIQEQ.ETLLE.EREEVTRELQ..RALRNI....ALLD...SRAQEA
  417-  462 (57.98/33.45)	REEMAGELKH.IQASiAALQH.EKQKI.QQ.Q..R.IESR....CWLDrwrSRGQAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.28|      11|      35|     241|     251|       8
---------------------------------------------------------------------------
  241-  251 (22.23/10.16)	FDPECTQPSSS
  278-  288 (23.05/10.76)	FDPQCYHNFSS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP19706 with Med32 domain of Kingdom Viridiplantae

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