<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19706

Description Serine/threonine-protein kinase
SequenceMELLSPTHPPLPMADHFSGFSPPTGFRRGFDRTSVTATSQPPEIVEEGGDRVHVAVGKSVDKAIALLRWSFEQFGNREICILHVHQPSPLIPTLLGKLPASQASTEVVSAFRRDEKERTRKLLSNYLSICTQSKVRASVTVTEASHVQKGIVDLVNEHGIRKLVMGATPENCMKVKTSSSKASYAAKNAPQFCEIWFVYKGKHVWTREAFESPSFVGSISQSEIATADNLREQCSQSELVFDPECTQPSSSRSIPCQGESVPIEAVLPPSLPCYINRFDPQCYHNFSSLTNTTSSSGYTSSADQRASSDSATKDDDEESLHDLLTEARIEAEASRDESFQEFLECKKLEAIGKFKALESARAHEIKLREEAEDALKMTIQEQETLLEEREEVTRELQRALRNIALLDSRAQEANHRREEMAGELKHIQASIAALQHEKQKIQQQRIESRCWLDRWRSRGQAAGATHNGVIGFSEDSLELAEFSLADLQIATCDFSESFKIGQSGYGSVYKGEMMDRTVAIKKLHPHNMQRQSEFLQEVQVLGKLQHPHLVTLIGTCPEAWSLVYEYLPNGSLQDRLSRRSNSCSLTWKIRARIIAEVSSALLFLHSCKPEKIVHGNLKPENIVFDSEVSCKICDFGIRKLMPEETLRCPSFRWGTELKGSFSYTDPEFSRTRSLTPKSDIYSLGLIILQLLTGRDPVGLASEVRKAVSCGKLSSILDSSAGEWPNFVAKQLMDLGLKCCELNSRDRPELTPSLVRELEQLYTLEERPAPSFFLCPILQEIMHDPQVAADGFTYEGDALCTWLENGSETSPMTNLKLDHLHLTPNHALKHAIRDWFLKS
Length838
PositionTail
OrganismActinidia chinensis var. chinensis
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> Ericales> Actinidiaceae> Actinidia.
Aromaticity0.07
Grand average of hydropathy-0.408
Instability index54.62
Isoelectric point5.87
Molecular weight93959.37
Publications
PubMed=29661190

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19706
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.01|      14|      18|      22|      35|       1
---------------------------------------------------------------------------
   22-   35 (27.48/16.58)	PPTGFRRGFDRTSV
   41-   54 (26.52/15.76)	PPEIVEEGGDRVHV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.57|      27|     118|     479|     534|       2
---------------------------------------------------------------------------
  497-  526 (46.01/77.08)	SFKIGQSGYGSV.YKGEMMDRTvaiKKLHPH
  650-  677 (46.56/15.09)	SFRWGTELKGSFsYTDPEFSRT...RSLTPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.22|      22|     476|     122|     174|       3
---------------------------------------------------------------------------
  145-  174 (27.59/78.92)	SHVQKGIVDLvnehGIRKLvMgatPENCMK
  626-  647 (42.64/18.17)	SEVSCKICDF....GIRKL.M...PEETLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     181.64|      46|      46|     368|     413|       6
---------------------------------------------------------------------------
  313-  365 (51.16/28.71)	KDDDEESLHDLLTEA.RIEAEaSRDESFQEFLecKKLEAIgkfkALES...ARAHEI
  368-  413 (72.50/43.53)	REEAEDALKMTIQEQ.ETLLE.EREEVTRELQ..RALRNI....ALLD...SRAQEA
  417-  462 (57.98/33.45)	REEMAGELKH.IQASiAALQH.EKQKI.QQ.Q..R.IESR....CWLDrwrSRGQAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.28|      11|      35|     241|     251|       8
---------------------------------------------------------------------------
  241-  251 (22.23/10.16)	FDPECTQPSSS
  278-  288 (23.05/10.76)	FDPQCYHNFSS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19706 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SSSGYTSSADQRASSDSATKDDDEESLHDLLTEARIE
294
330










Molecular Recognition Features






MoRF SequenceStartStop




NANANA