<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19667

Description Mediator of RNA polymerase II transcription subunit 29
SequenceMNLPPMQQPGPGVMPQVQQQPGPGTPQQAQQMQQPMPQQQQEKLDNISKVKSLITPLRESLAVTLKNAAATLQQNNLKTSIECLSQGAASQRYLPLQVALTRTDPMPGQEILTYPQYLATVRAQVGFAKEVHDMLVGAAQNVSPGE
Length146
PositionTail
OrganismBlattella germanica (German cockroach) (Blatta germanica)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blaberoidea> Ectobiidae> Blattellinae> Blattella.
Aromaticity0.03
Grand average of hydropathy-0.484
Instability index62.87
Isoelectric point7.87
Molecular weight15867.03
Publications
PubMed=29403074

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP19667
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.63|      12|      19|       4|      20|       1
---------------------------------------------------------------------------
    4-   20 (19.40/14.93)	PP....MQQPgpgvMPQvQQQ
   26-   41 (23.22/ 6.45)	PQqaqqMQQP....MPQ.QQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.37|      13|      18|      57|      70|       2
---------------------------------------------------------------------------
   57-   70 (15.46/17.51)	LRESLAvTLKNAAA
   77-   89 (21.91/18.11)	LKTSIE.CLSQGAA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP19667 with Med29 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MNLPPMQQPGPGVMPQVQQQPGPGTPQQAQQMQQPMPQQQQEKLDNISKV
1
50

Molecular Recognition Features

MoRF SequenceStartStop
1) RYLPLQVAL
92
100