<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19656

Description Uncharacterized protein
SequenceMMGFSYEKRALKRPRLGPPDVYPQEPKQKEKEELNTLPDTGRKRQQINPKDNFWPATARSKNAIEAWFKDLAGSKPLSSLSKKYQVPMLRAAWFIKLSYAYTVAVSEVKIKKRQLPDPSQEWTATLIKFLKDQLSKLQDFYHQSGGSGSGGGNSNATNSNSGSGIASGSNTNSNSNSGSNNTATNNAAANNSATSGTAVSNGSAANPNSNSNSGNTNSNASSSGNTNTSTGAGTPQPSASSSTPTPSVSASTPSMTDEQKLSQRQWQYCIQIAKYLYEEGLLERQEFLQWILELLDKMRSAPADDGILKLLLPLALQYLDEFVQSELLARKLAYLCAKKLAQLCSVASDVAANTNVLSSSPVLPPSASPQSPILPGNSVSVLSQTGATQQTSVNPLIVTFSEYMSCPHHRDLVLGLSAILQAITLDCPTALVWNCVGEGKSHSVLNGSPLDHLPCTPSTLPMPQRTNNPTTRRQLRVAEDHVRNRSRAAEGRWSCDKWQQSSAGRTTSKTLLQDEAVVQILCEWAVSSQRSGEHRAMAVAKLLEKRQSDLISGESDAADEKDSVSSANGAPTGLPVFQPLLMRFLDNDAPILEENPSAHNRAMFTNLVHLFSELIRHDIFSHDVYMCTLISRGDLNTGGPASATPHHPTSNKPATPAESRGTVNNSSMQDDDGSLFPGIDIKPSKLDVQDHARNMDYDDSKIDDDLDKLLQHIKEEQQNSLDAPDSPKDDGVPPGSLVAPPIASVTPMEGVETGGPGEMRSRHLLYTTHFPLPQDEPCCLHDCNQRHVLLYGVGKVRDEARHTVKKMTKEICKLFSKKFSIDVAEGGKVKKHSRGEFNFEATTAKVQGLSYFDQHVVTWQCAVTVVEMLSSFAMSPEQTTAVFEGMCRLVKHVTNPGDCSSAERCVLAHLYDLYSSCSLLKSKPHSVEPFGNAYPKIRQALYSTVQPSSSNHVCNAQFMADVFSNPRRGGRIEPQWARQLAETPNNRYSFVCNAVVAVCNETDNDRLNDLAILCAELTACCNSLSAEWLGVLMALCCSSNHSSHFIDVLAQVDVQDLSIHNSLAVFTSILIETIIESYSWIESTFIVIGGKMSDSGDTSHECDEIMKKRKNAVEFPKHTVIKRARVKNEAYINWKGDRVEPKHHGYDCKKKPKGQSYVYWLSGSEGRGDADIEAEAGARLTCHLLLRLFKTVECPQPALYSVGTSPHPMPCTSTPGYYSIKLSCDRHLLAAAHNNIRVGPVLAVLKAILVVGDATAREGKTPSSKSKPEQSQQLHSSSSGGSSNKTQISGSSGGELSISHILGTSDILGGGDDPLLDLGPISSAVGGSTNTMETAAGLSDFAQHVLRQICSQEWVLERCLQNPEKLCHTDMLLDSMLTPKQAQRLLHMICYPDTTAATEESLDQRHIIARILENLDQWTLRMSWLDLQLMFTQFQQGSSELNQWLDTVAKAAIDVFQLTSTSSSSSSSSGDNKDEKRSALRPSKPGSIWLVAPLVSKLPSAVQGRVLKVAAPNSLPDAERLSNYEDPKGRALMQDALQLRFSLVGGMFDTIQRNTTVTTDWAILLVQLISYSVIDLNNNAELFTTVIDMLATLIHSTLVSDSQSEKEENRKHYQNLMKKLKKGLQVFEKQRVSPWDLLEGHKNPAPLSWSWFGAVRMERKPLWYEDTHRLLKYHTHSLLKSPSYFLDPPPLPPEDLDPPQEKPVSIIFIFTFLLPF
Length1716
PositionKinase
OrganismBlattella germanica (German cockroach) (Blatta germanica)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Polyneoptera> Dictyoptera> Blattodea> Blaberoidea> Ectobiidae> Blattellinae> Blattella.
Aromaticity0.06
Grand average of hydropathy-0.397
Instability index46.49
Isoelectric point6.42
Molecular weight188330.52
Publications
PubMed=29403074

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19656
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.05|      15|      15|     189|     203|       1
---------------------------------------------------------------------------
  156-  169 (23.51/10.90)	ATNS.NSGSGIASGS
  189-  203 (24.89/12.03)	ANNSATSGTAVSNGS
  235-  249 (19.66/ 7.74)	PQPSASSSTPTPSVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      62.48|      13|      15|    1020|    1032|       2
---------------------------------------------------------------------------
 1020- 1032 (25.39/14.85)	CCNS.LSAEWLGVL
 1036- 1049 (19.34/ 9.36)	CCSSnHSSHFIDVL
 1059- 1070 (17.75/ 7.91)	IHNS.L.AVFTSIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.37|      15|      15|     304|     318|       3
---------------------------------------------------------------------------
  304-  318 (24.96/15.72)	DDGILKLLLPLALQY
  320-  334 (24.41/15.20)	DEFVQSELLARKLAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.60|      14|      16|      38|      51|       4
---------------------------------------------------------------------------
   38-   51 (27.16/16.23)	PDTGRKRQQINP..KD
   55-   70 (17.44/ 7.71)	PATARSKNAIEAwfKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.51|      16|      16|    1353|    1368|       5
---------------------------------------------------------------------------
 1353- 1368 (30.82/22.36)	EWVLERCL..QNPEKLCH
 1370- 1387 (21.69/13.22)	DMLLDSMLtpKQAQRLLH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      26.30|       8|      16|    1492|    1501|       8
---------------------------------------------------------------------------
 1492- 1501 (10.42/ 9.69)	APlvSKLPSA
 1511- 1518 (15.87/ 7.37)	AP..NSLPDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.75|      15|      16|    1301|    1315|      11
---------------------------------------------------------------------------
 1301- 1315 (25.48/16.43)	ILGTSDILGGGDDPL
 1318- 1332 (25.27/16.21)	LGPISSAVGGSTNTM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.01|      17|      17|     359|     375|      12
---------------------------------------------------------------------------
  359-  375 (31.38/17.36)	SSPVLPPS.ASPQSPILP
  378-  395 (23.63/11.10)	SVSVLSQTgATQQTSVNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.09|      16|      17|     813|     829|      13
---------------------------------------------------------------------------
  794-  826 (12.77/12.01)	GKVrdearhtvkkmtkeicKLFSK.KFSIDvAEG
  827-  843 (24.31/18.28)	GKV................KKHSRgEFNFE.ATT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.63|      16|      18|     521|     536|      14
---------------------------------------------------------------------------
  495-  510 (17.34/ 7.08)	.CDkWQQSSAGRTTSKT
  521-  536 (29.54/17.84)	LCE.WAVSSQRSGEHRA
  542-  557 (24.75/13.62)	LLE.KRQSDLISGESDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.83|      21|      23|    1113|    1134|      15
---------------------------------------------------------------------------
 1113- 1134 (33.97/32.42)	VEfPKHTVIK.RARVKNEAYINW
 1139- 1160 (37.87/29.54)	VE.PKHHGYDcKKKPKGQSYVYW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.55|      21|      23|     746|     766|      16
---------------------------------------------------------------------------
  746-  766 (39.91/23.34)	T..PMEGVETGGPGEMR...SRH.LLY
  768-  791 (33.52/18.33)	ThfPLPQDEPCCLHDCN...QRHvLLY
 1208- 1229 (23.12/10.19)	...PMPCTSTPGYYSIKlscDRH.LL.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.89|      23|    1126|     131|     153|      18
---------------------------------------------------------------------------
  131-  153 (43.06/21.99)	KDQLSKLQDFYHQSGG........SGSGGGN
 1265- 1295 (33.83/15.76)	KSKPEQSQQLHSSSSGgssnktqiSGSSGGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.42|      15|      19|     258|     272|      21
---------------------------------------------------------------------------
  258-  272 (28.68/14.93)	EQKLSQRQ..WQYCIQI
  278-  294 (20.74/ 9.06)	EEGLLERQefLQWILEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.81|      11|      24|     923|     933|      22
---------------------------------------------------------------------------
  923-  933 (20.99/11.83)	KPHSVEPFGNA
  946-  956 (19.82/10.71)	QPSSSNHVCNA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19656 with Med12 domain of Kingdom Metazoa
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