<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19646

Description Uncharacterized protein
SequenceMSTISDFHAHTLAVASVYPSPTATSTQTRDSDSSSSFVGNTPSTVLFFLAMLVGVAIAFVFIFFTMRYFVRSRYGLHIYPVAHHGMMFTANVGPDRVALSHSPSDRELDWYLTYLRNNHFFRDDFFERRYLSAVEGLDALAAGRRRRRRRRGRYLKMKKLTVAQVDCLFPKTSYAEWLHNGDTEDDLALVRMDMDGENEKVNATTTVQGDFEVIELRRLSSPDHTTPDIDATSLATSNVKTELHFDSGSCAICLDTYEPDDVVRGLICGHVFHAECVDPWLTRRRACCPICKRDYYKENNREANVTERPEGHVNNTNTERAEENRTEENRTDEHRAEDLSQPQEVDLAEAGNTTDRETDNNTTHTEEDFTINYDVLRNDPNLRNLLNELIPLSERANAILRGQDTLDLELAARVVANKKFSNCWKRSFWRLMGISKEDMFNWAVISLYSEEQAQQAEEGRDDVSHDFPVLHLPHVAPETLDGPAAQETVQMEQIALTETPEAQQNESRRSPRRSQESEHSVYHNAEDNAEDLAEAAREVVDRRKNVRKMDLGSFLNDESVGGGLWADAEVDMSSIGVPVGGSSGAPVLRSTEFSEQYARRDREEIPIPDAPPYKARVGNLPYDATEPALTRFFEDRLQARDIVTEVKLPLDNMTGKPKGFAFVTFSERAALEEALNLTMSEFNGRKMYVNVAAPQKTDVFDLDWRLARGPPGGGRRDREREEVDLDWGAARSSGPVGGGGRERGPRGPRREEPDLDWGSARGSGALPPREPRERRARPDEPELDWGSARNASGPLPPRERKPRRDEPELDWGAARGSGGPLPPRERLNRKPREDNLDWTRGGAAAPKKKDEKEFDWKRGQALEPRKKEAPKKKEEAAAGPQKSLYDVLSVDDDEDEEETGLEQKVADVKLDPSPLDNLLKMYGLEPIAKLLERTKPDGSKGVKLRKSYKNHIQDLPGKHQIPPAKAVPAALLDPNLSQQPDLIHEIDADLLNHALKFEKTPVNGIPGFNPAELAISDQLTLMRGDDMSENDENKKKRKKKQASVDAKRQHI
Length1051
PositionHead
Organism[Candida] pseudohaemulonis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.07
Grand average of hydropathy-0.814
Instability index53.10
Isoelectric point5.40
Molecular weight118465.54
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
RNA binding	GO:0003723	IEA:UniProtKB-UniRule
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19646
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     252.30|      24|      25|     777|     800|       1
---------------------------------------------------------------------------
  696-  715 (37.66/13.22)	KTDVFDLDWRLAR...GP........P...GGG...R
  720-  748 (38.27/13.53)	R.EEVDLDWGAAR.SSGPVggggrerG...PRG...P
  749-  774 (44.60/16.75)	RREEPDLDWGSAR.GSGAL.......PprePRE...R
  777-  800 (54.72/21.89)	RPDEPELDWGSARNASGPL.......P...PRE...R
  803-  829 (49.55/19.26)	RRDEPELDWGAARGSGGPL.......P...PRErlnR
  850-  867 (27.49/ 8.06)	..DEKEFDWK..RGQA..L.......E...PRK...K
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.75|      32|      63|     910|     941|       2
---------------------------------------------------------------------------
  910-  941 (55.70/34.82)	LDP..SPLDNLLKMYGLEPIAKLL..ERTKPDGSKG
  972- 1007 (47.04/28.23)	LDPnlSQQPDLIHEIDADLLNHALkfEKTPVNGIPG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19646 with Med19 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FDLDWRLARGPPGGGRRDREREEVDLDWGAARSSGPVGGGGRERGPRGPRREEPDLDWGSARGSGALPPREPRERRARPDEPELDWGSARNASGPLPPRERKPRRDEPELDWGAARGSGGPLPPRERLNRKPREDNLDWTRGGAAAPKKKDEKEFDWKRGQALEPRKKEAPKKKEEAAAGPQKSLYDVLSVDDDEDEEETGLEQKVADVKL
2) GSKGVKLRKSYKNHIQDLPGKHQIPPAKAVPAALLDPNLSQ
3) LHLPHVAPETLDGPAAQETVQMEQIALTETPEAQQNESRRSPRRSQESEHSVYHNAEDNAEDLAEAAREVVDR
4) LTLMRGDDMSENDENKKKRKKKQASVDAKRQHI
5) NNREANVTERPEGHVNNTNTERAEENRTEENRTDEHRAEDLSQPQEVDLAEAGNTTDRETDNNTTHTEEDFTINY
700
938
470
1019
299
910
978
542
1051
373










Molecular Recognition Features






MoRF SequenceStartStop




1) KKKDEKEFDWKRGQALEPRKKEAPKKKEE
2) LDWTR
3) VKLRKSYKNHIQDL
847
836
942
875
840
955