<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19645

Description Myosin-1
SequenceMAIVKRGGRSKVKQQEAPARSGIKKAEFDLHKKKEVGVSDLTLLSKISDESINENLHKRFMNGTIYTYIGHVLISVNPFQDLGIYTKQTLNMYKGKNRLEVPPHVYAIAEAMYYNLKSYGDSQCVIISGESGAGKTEAAKQIMQYIANVSVDDQLNGSSSSSGIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIYFNPQNYQPIAAHITNYLLEKQRVVQQITNERNFHIFYQFTKHCPQQYQQLYGIQGPETYIYTSAARCTSADGIDDGKDFSETLNAMNIIGLQQVEQDNIFRMLAAILWIGNISFVENEEGNAAVRDEGVTNFVAYLLEVDAELLKKAIVERIIETSHGMRRGSTYHVPLNIVQAIALRDALAKGIYNNLFEWIVERVNRSLKDPSQNYEKKSVGILDIYGFEIFEQNSFEQICINYVNEKLQQIFIQLTLKAEQEEYVQEQIQWTPIEYFNNKVVCDLIEATRPQPGLFAALNDSIKTAHADSDAADQVFAQRLSMVGASNKHFEDRRGKFIIKHYAGDVTYEVSGMTDKNKDNMLRDLLEVLSTSSNAFVTAELFPPQLLAAVTDSKKRPETASDKIKKSANVLVDTLSQCQPSYIRTIKPNQTKRPKEYENQQVLHQIKYLGLKENVRIRRAGFAYRTTFDKFVQRFYLLSPKTGYAGDYIWHGDDITAVKEILRSCHIPPTEYQLGTTKVFIKTPETLFALEDMRDKYWHNMAARIQRAWRRYMKRKEDAAKVIQTAWRTKKHGNKFEQLRDKGTEILGGRKERRRMSLLGSRAYMGDYLGCNQPSGYGRFVVSQAGINEYVVFSGKGEILLSKFGRSSKRLPRIFILTNSNLYVVAEVVVEKRLALQKEFTLPINGINYLGLSSFLDNWLAVSMHQASAATPDIFISLDFKTELVTHLKQLNRGITVKIGPTIEYQKKPGKMHTVKIIVGASSAHGDTYKSGNVTVGQGLPASSRNPKRPRAKATSVDYQKYYNRGAQMRSNAQNYNNLHSTQNNGSHALLQLAAAHAYQQSQPRSVPPPATHTQPGLKQLKRPPPAPPGIAQAGQNAQQQSQAKPPPPRPVKKTAAPQPPAKSTRAPEVKRSTPQPPPPPPAPPSKPARQPKFPTYRVLFDYDGSVAGSVALVKDSVVYVASVNGKWGLVKDLDETYEGWSPMDYMEEIDPPADLFSNNVSQPAPQAPSVPTPQALQATASEPQANSSERPAMLPTTSSGNGLGNGLADAILAKKSGDVTLAGSLADALKKRKGATGNDSDDEEDDDDEWPSVTIYPLDDTLSQKTFPDYSPWEEDRDLTKKLENLNYLNKGFFETPRVSNEYYSARNLVQETVFSSSKNCNSILRELSQHLTKSYKTRDEVINKIRASSFSFKIPLRVTLTALKKEAWLKELANPDQPLHKISSRIPHGLRNKVLVDAMCSRQVPISRAIWFTKCSLFSELVLVKKKALVRQHSLTLANSSSITRSNDVLERRWLQEWTQQVADYVLKFSKEMKAVSSHELKIRFQERMNYLILYVLAMYIEELLDKTFFLTLILRLIKEDHFTGTLDILTLTELQKIDLSETSDADQKYLDVLSKQLTEFGQLLIALIFIRVFWKDIIAESFLRKHLSESLLLNYLIVSKLPTLSEKPTIARIEVPHAIKSECLSLMSEMIIELFHKSSSSFIIPSSWIVLGDVLHNIINSSNLYNDPPKRALLEKSLALLKFRNESLIVNCGGDSTSPSAREDGSPNVVLHEQALSHAYIHRSNDDVLKLIDLLDHQKLREAFTLIFTPGSPNKARSAQPQSIRLKAMIFWCVSTYRDMGVSKEKLISVCNALKMHGTQATGKSSVKLRIKLENEILESIFCLAELPSSELSHTNLYVLVNELYQLKIITISAYLRKLIASGIFYLSSKPTDEKRLDDLDPQSRFHLLLLQNLPLLNNRQCDHILKKWAKEQIDFIGLFEQATRTLREGVLDHILNNTIGKADLGVFESISELNVGLQFMVMNWFTSEFKTSISKASKLVHITPDVVAFVYELFIKSNNLTAFFKLFIKFILKNENKVLIFYMDSLYFISRLILDHSTLLEFIAGNSSESPSASLDIFKLIVQDYRDLLSRETDIFQFGPLWEHIRRQLQSPGIRRRNSPNESSEANSLGRRPASTSPEFNESKSSESSYETEFIIEEVQSLESFEKRSLTADEYKDITEDLCSFCGVTLDYFTAELPIAQIKLLLRSIEKDMGQKTEIQIFKLISNIKAKETSKEDDLGVALKELMEENLDIERFSLVTKFILALDLMTCDTLLSTIQNISAPTVYEKRLRDDLFEEVAPVILSRSVSILFQSVRLKYKENHLEASIEIVVTANLPYDNTSLKFRGELLCMIVQHPVKTVQSITKHFNQLEMLDIMSNLLGVSSSGFESAKISSIVPIMSEFNLPIVQVIISILAQQNDDVEAILNPLLSREDFFLNASFFGELFNLCDLRFRIMVFKQMESLFLNKSLSMITSADLAPESLTPIFKDFFSKINDSFVDKIDLSASDYKDLLSYISQFISCVEGFDGSNELAKMLLDNTSILLRIIIIQSGSLIDLMMQLDLQHFELIHQLVRLFNTKFMMHSNERLKILLYDLLHLFKNSLTQQLTLRAEEDESVPVESPSIPKSISDQGASDEPSSNERVKRPPKESISTILTILDIPEPTNHSIQTDEGAVAECLIMLDRDELLRRSDIKSFNNNSLVLASSRESGAFDSPFGELSRDENTSWPFTIRSVQLIEETGGGINDGCINLALLRAYTTKENVP
Length2784
PositionKinase
Organism[Candida] pseudohaemulonis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.08
Grand average of hydropathy-0.288
Instability index48.05
Isoelectric point7.32
Molecular weight314541.11
Publications









Function






Annotated function


GO - Cellular Component
actin cortical patch	GO:0030479	IEA:UniProtKB-SubCell
mediator complex	GO:0016592	IEA:InterPro
myosin complex	GO:0016459	IEA:UniProtKB-KW

GO - Biological Function
actin binding	GO:0003779	IEA:UniProtKB-KW
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
motor activity	GO:0003774	IEA:UniProtKB-UniRule
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19645
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      97.39|      16|      16|    1044|    1059|       1
---------------------------------------------------------------------------
 1050- 1065 (31.59/19.09)	TQ.PGLKQLKR....P.PPAPP
 1085- 1100 (21.35/ 9.87)	PR.P.VKKTAA....PqPPAKS
 1101- 1121 (21.57/10.07)	TRaPEVKRSTPqpppP.PPAPP
 1193- 1208 (22.89/11.25)	FS.NNVSQPAP....Q.APSVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.30|      37|      53|    1770|    1822|       2
---------------------------------------------------------------------------
 1770- 1812 (45.86/61.86)	LIDLLDHQKLREAFTlifTPGSPNKARSAQPQSIrLKAmIFwC
 1826- 1862 (62.45/31.48)	LISVCNALKMHGTQA...TGKSSVKLRIKLENEI.LES.IF.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     195.95|      50|      52|    2207|    2256|       3
---------------------------------------------------------------------------
 2207- 2256 (77.07/50.82)	GVTLDYFTAE.LPIA...QIKLLLRSIE...KDMGQKTEIQIFKLISNIKAKETSKE
 2260- 2308 (66.50/42.71)	GVALKELMEEnLDIE...RFSLVTKFI....LALDLMTCDTLLSTIQNISA.PTVYE
 2310- 2362 (52.38/31.86)	RLRDDLFEEV.APVIlsrSVSILFQSVRlkyKENHLEASIEIV.VTANLPYDNTS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.58|      36|      89|    2388|    2423|       4
---------------------------------------------------------------------------
 2388- 2423 (59.45/34.97)	FNQLEMLDIMSNLLGVSSSGFESAKIS..SIVPIMSEF
 2425- 2451 (28.61/12.79)	...LPIVQVIISILAQQNDDVE....A..ILNPLLS..
 2478- 2510 (46.52/25.67)	FKQMESL.....FLNKSLSMITSADLApeSLTPIFKDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.13|      19|      89|     488|     506|       5
---------------------------------------------------------------------------
  488-  506 (33.95/22.79)	PGLFAALNDSIKTAHADSD
  580-  598 (33.17/22.08)	PQLLAAVTDSKKRPETASD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     139.79|      35|      93|    1599|    1633|       6
---------------------------------------------------------------------------
 1599- 1633 (56.32/34.35)	FGQLLIALIFIRVFWKDIIAESFLRKHLS......ESLLLN
 1661- 1687 (37.22/19.95)	ECLSLMSEMIIELFHKS..SSSFI...IP......SSW...
 1690- 1730 (46.24/26.76)	LGDVLHNIINSSNLYNDPPKRALLEKSLAllkfrnESLIVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.43|      24|      29|    1922|    1945|       7
---------------------------------------------------------------------------
 1922- 1945 (43.27/25.89)	QSRFHLLLLQNLPLLNNRQCDHIL
 1952- 1975 (41.15/24.27)	QIDFIGLFEQATRTLREGVLDHIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.65|      14|      15|    1235|    1248|       8
---------------------------------------------------------------------------
 1235- 1248 (24.59/13.19)	SSGNGLGNGLADAI
 1253- 1266 (23.06/11.94)	SGDVTLAGSLADAL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.35|      14|      15|    1139|    1152|       9
---------------------------------------------------------------------------
 1139- 1152 (24.42/16.26)	YDGSVAGSVALVKD
 1156- 1169 (25.92/17.79)	YVASVNGKWGLVKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.98|      15|      16|     732|     746|      10
---------------------------------------------------------------------------
  732-  746 (31.19/23.24)	KYWHNMAARIQRAWR
  750-  764 (26.79/18.82)	KRKEDAAKVIQTAWR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.14|      25|      89|    2094|    2118|      11
---------------------------------------------------------------------------
 2094- 2118 (44.26/24.95)	SLDIFK...LIVQDYRDLLSRETDIFQF
 2181- 2205 (32.36/16.30)	SLESFEkrsLTADEYKDI...TEDLCSF
 2520- 2539 (30.52/14.97)	..DKID...LSASDYKDLLSY...ISQF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.10|      12|      16|     811|     822|      12
---------------------------------------------------------------------------
  811-  822 (22.09/16.00)	SGYGRFVVSQAG
  830-  841 (21.01/14.77)	SGKGEILLSKFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.32|      16|      16|    2133|    2148|      13
---------------------------------------------------------------------------
 2133- 2148 (27.34/15.38)	GIRRRNSPNESSEANS
 2150- 2165 (27.98/15.93)	GRRPASTSPEFNESKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.53|      16|      16|    1287|    1302|      14
---------------------------------------------------------------------------
 1287- 1302 (29.20/17.98)	WPSVTIYPLDDTLSQK
 1304- 1319 (30.33/19.00)	FPDYSPWEEDRDLTKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.02|      16|      37|    1030|    1046|      15
---------------------------------------------------------------------------
 1016- 1031 (24.07/ 8.17)	HSTQNNGSHALLQLAA
 1033- 1048 (31.96/19.42)	HAYQQSQPRSVPPPAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.24|      18|      21|    2630|    2649|      20
---------------------------------------------------------------------------
 2630- 2649 (27.67/22.46)	RAEEDESVP...VESPsiPK.SIS
 2651- 2672 (23.58/11.90)	QGASDEPSSnerVKRP..PKeSIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.51|      15|      31|    1341|    1355|      26
---------------------------------------------------------------------------
 1341- 1355 (24.74/14.44)	YSARNLVQETVFSSS
 1373- 1387 (24.77/14.47)	YKTRDEVINKIRASS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19645 with Med12 domain of Kingdom Fungi
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