<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19638

Description Uncharacterized protein
SequenceMAINDDFLSVQYAQKDLRGASKLPLSALRISPIPTAQDRESRLERPAVSARNKRARKRNTLAATRRLAGPGFQFDVDVDENTVQSTPETLVTDYDLDDEVVHKPAEEENTQVKRLAGYLLESGRAMNVRYNVVDPLDDKKETGPGASNKKQLQISRTTKNRKETVMGMLSLKYHWLAKCQEDYNSDDIKYPGVEGVYNPLQVIRNRAIRAKYHEPAPPLRFANVPLACNVFSSHKKAGGKPWRMLWGIELNELVNDEAWRSLHWKELRNPKGELWFSDSRPPPRSVISFDTPSKPPRSSRLHDKLWGDVDTEDRSSSRSKSPSTKSIRKNIRDKAKRLYGNANSAGNSNSDVDSSSNEPAKSTESFLKLKQSSKSDSDSNIGHIFQIPRNLESSGSSEAQRSQPELPKIKIDTNAVSKDDISSKHETLHLEETNGNRSKMNLDDVQITPLHARSHLSSAHIVTSTESSKSPEVDSKELKFMDASAHGRSLELQLVLSESFMTSVFPRLVDTTSMKLNHILNKDINVLLHDIVLVNDSQLPAHEAFYTGFLSECKSLMHVINDEYAVKIDHLLSATDRSIGEINTSLSLDMKKVNENLDRVNQSLFGSIVTTSVSDRDVTFTDGGNYKILYFVLENAIVVLLRVTWFVVNIYKELLAVENLTLESDAHNIIRLCKDLLSITRGLRETWCLDTMKVRPEGEDHKASEEDVQRVFEEFNKLTEKISALERS
Length728
PositionHead
Organism[Candida] pseudohaemulonis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.06
Grand average of hydropathy-0.614
Instability index50.51
Isoelectric point6.73
Molecular weight82108.45
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19638
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.12|      18|      23|     408|     430|       1
---------------------------------------------------------------------------
  408-  425 (29.66/19.87)	KIKID....TNAVSKDDISSKH
  439-  460 (26.46/ 7.81)	KMNLDdvqiTPLHARSHLSSAH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.75|      15|      32|     303|     317|       2
---------------------------------------------------------------------------
  303-  317 (28.10/13.82)	DK...LWGDVDTEDRSSS
  333-  350 (19.65/ 7.66)	DKakrLYGNANSAGNSNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.32|      21|      23|     634|     655|       3
---------------------------------------------------------------------------
  626-  650 (26.50/24.58)	YKILyfvL..ENaIVVLLRVTWFVVNI
  651-  672 (26.30/18.47)	YKEL...LavEN..LTLESDAHNIIRL
  673-  687 (15.52/ 7.67)	CKDL...L....sITRGLRETW.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.79|      16|      21|      59|      79|       5
---------------------------------------------------------------------------
   59-   79 (23.33/27.33)	NTLAATrrlagP.GFQFDVDVD
   81-   97 (24.46/14.79)	NTVQST.....PeTLVTDYDLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.76|      15|      33|     466|     480|       6
---------------------------------------------------------------------------
  466-  480 (25.76/12.61)	ES...SKSPE.VDSKELKF
  498-  516 (17.00/ 6.26)	ESfmtSVFPRlVDTTSMKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.57|      12|      37|     351|     362|      12
---------------------------------------------------------------------------
  351-  362 (19.92/ 9.53)	DVDSSSNEPAKS
  391-  402 (17.65/ 7.65)	LESSGSSEAQRS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19638 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DISSKHETLHLEETNGNRSKMNLDDVQITP
2) IPTAQDRESRLERPAVSARNKRARKRNTLA
3) RSSRLHDKLWGDVDTEDRSSSRSKSPSTKSIRKNIRDKAKRLYGNANSAGNSNSDVDSSSNEPAKSTESFLKLKQSSKS
4) SDSNIGHIFQIPRNLESSGSSEAQRSQPELPKIKIDTNAVSK
5) YNVVDPLDDKKETGPGASNKKQLQISRTTK
420
33
297
377
130
449
62
375
418
159










Molecular Recognition Features






MoRF SequenceStartStop




1) FLKLKQ
366
371