<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19632

Description Uncharacterized protein
SequenceMNNMAAPMGGTWHLEQNPDERQKVILIVMQTLRDLQGANYNEAGASKLAHEFEKYVFLKAASRDEYLTAIKQKVHQMRGSLRNQGQQPQSQLQNQNQPNQGNQAMNRQAFQARQQQAKQAQAQQAQQSQQAQQAQQAQQAQMGMGMNNDMNFFPQNQMMRNGMMNQGMSRPNSQMGMQNNSVGSQASAANSGSAATSAPSSAPSGNNATGGRPSLTSQQMQQLSTMIKNVPIPPPLLNKIPNLPPNVNTWARIFELAQNKAIPPASVPAIKEIHNAHLLIVMQQHQQRLAQRRVGSTGGQNADQNINSMNNMNGMNNMNRQSQGQMNMQNQRMQQQQQQQQQQQPQQQPAFKNNKPQGGQNMQLNMGMQRPQSQQNQQQQNQQNPMMKQQNQQPQQQLQQQNQQVQGNNNLGMANQAGGQQQAAPMKMPNFQITPQDMMDYQADALAYLSRAQQEGKIPPNLDNAGKQNFIRKFIYHLKANAFKNEQAKANKAAGQMNMAPQHPQRTPQQLLMQMGNVNQGGFPHQQYQQQQQLNQNQQQQPPQSQQQPMGGMQQGMGQPQQSPMMGNMQQPNASQMMNQGANQTMFSPVMQQKAPMQGSQGNMGNMAGQQNQARRPMGVPPITDEMKMKLKSLFDEVARSDNHNLSNHTNTLTDSDKFRFKELMTKISQQYGTVDHVLTYYYVLHRDLNGTKKLIQMKFMTKNIIEGFQKGLYLARPELLEKVVQYFQRYFDSVKKELAARRQQQQQQQPQKLDQTTNQMSPAQQRPAMNQPAAQVPNQRPLSAMQPMQQGDQRFMPQNVPQSAQQNFGPPGMGQMPMGQNMSPQQQHQQPPQQPVPQAQQQMANQRVPQQQTQQQFARNATYGQIAQGQPDWLKAVNAQQRGANISPMPVAQNTSPQMQTQTAPKAAAKPAKKTSTSGAAGRRKSTKAAGTMPTPGNSAPTPATLANAIKTPNSMPTPQVIQSNSNKGTPIDVSPHSDNKGNNVMGKEPIVGDVFGGNQVDSKLDSRRELSKTNPEQFFFAALSNLLETDKAEGTNGTKAANTDNTKSPLSPNSVEWTCNVKPEAITSAFRQVDFIKELTNMEVLEECAKLVERDAIKKEQEASSSKKREREEPDDIDMLFDEADTKKVKTEDFDRYMYEPVDFDDWKQWLTGLQQTKV
Length1161
PositionTail
Organism[Candida] pseudohaemulonis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.05
Grand average of hydropathy-1.056
Instability index53.66
Isoelectric point9.78
Molecular weight129997.53
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19632
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     412.41|      52|      52|     307|     358|       1
---------------------------------------------------------------------------
  157-  210 (48.79/ 7.66)	QMMR..NGMMNqgMSR.PN.SQMGMQNNS........VGSQASAANSGSaatsaPSSAP..S..GNNATG
  307-  358 (106.04/27.05)	NSMNNMNGMNN..MNRQSQ.GQMNMQNQR........MQQQQQQQQQQQ.....PQQQP..AFKNNKPQG
  386-  437 (51.35/ 8.52)	.....M..MKQ..QNQQPQ.QQLQQQNQQvqgnnnlgMANQAGGQQQAA.....PMKMP..NFQIT.PQD
  551-  594 (46.84/ 7.00)	......GGMQQ.gMGQPQQ.SPM.MGN..........MQQPNASQMMNQ.....GANQT..MFSPVMQQK
  595-  630 (48.41/ 7.53)	APMQG............SQ.G..NMGNM............AGQQNQARR.....PMGVP..PITDEMKMK
  759-  813 (62.27/12.22)	NQMSPAQQRPA..MN.QPA.AQ..VPNQR....plsaMQPMQQGDQRFM.....PQNVPqsAQQNFGPPG
  870-  920 (48.71/ 7.63)	GQPDWLKAVNA..QQRGANiSPMPV.AQN........TSPQMQTQTAPK.....AAAKP..A.KKTSTSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      65.05|      15|      15|     940|     954|       3
---------------------------------------------------------------------------
  940-  954 (25.93/14.66)	SAPTPATL.ANAI..K.TP
  956-  972 (18.88/ 8.36)	SMPTPQVIqSNSN..KgTP
  975-  991 (20.23/ 9.57)	VSPHSDNK.GNNVmgK.EP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.35|      15|      16|     517|     532|       4
---------------------------------------------------------------------------
  371-  385 (29.15/ 6.78)	PQSQQNQQ..QQNQ.QNP
  525-  542 (23.20/ 6.68)	HQQYQQQQqlNQNQqQQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.64|      15|      34|     228|     242|       7
---------------------------------------------------------------------------
  228-  242 (28.11/16.94)	KNVPIPP...PLLNKIPN
  245-  259 (23.83/13.17)	PNVNTWA...RIFELAQN
  260-  275 (17.70/ 7.76)	K..AIPPasvPAIKEIHN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.90|      19|      34|     649|     667|       9
---------------------------------------------------------------------------
  649-  667 (33.29/29.59)	HTNT........LTDSDKFRFKELMTK
  677-  703 (25.61/20.63)	HVLTyyyvlhrdLNGTKKLIQMKFMTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     128.49|      45|     435|      39|      88|      10
---------------------------------------------------------------------------
   39-   88 (66.49/48.75)	NYNEAGASKLaheFEKYVF.LKA.ASRDEYLTAIK.................QKVHQMrGSLrNQGQQP
  461-  524 (62.01/31.38)	NLDNAGKQNF...IRKFIYhLKAnAFKNEQAKANKaagqmnmapqhpqrtpqQLLMQM.GNV.NQGGFP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19632 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ELAARRQQQQQQQPQKLDQTTNQMSPAQQRPAMNQPAAQVPNQRPLSAMQPMQQGDQRFMPQNVPQSAQQNFGPPGMGQMPMGQNMSPQQQHQQPPQQPVPQAQQQMANQRVPQQQTQQQFARNATYGQIAQGQPDWLKAVNAQQRGANISPMPVAQNTSPQMQTQTAPKAAAKPAKKTSTSGAAGRRKSTKAAGTMPTPGNSAPTPATLANAIKTPNSMPTPQVIQSNSNKGTPIDVSPHSDNKGNNVMGKEPIVGDVFGGNQVDSKLDSRRELSKTNP
2) KFIYHLKANAFKNEQAKANKAAGQMNMAPQHPQRTPQQLLMQMGNVNQGGFPHQQYQQQQQLNQNQQQQPPQSQQQPMGGMQQGMGQPQQSPMMGNMQQPNASQMMNQGANQTMFSPVMQQKAPMQGSQGNMGNMAGQQNQARRPMGVPPITDEM
3) MKLKSLFDEVARSDNHNLSNHTNTLTDSDKFR
4) TAIKQKVHQMRGSLRNQGQQPQSQLQNQNQPNQGNQAMNRQAFQARQQQAKQAQAQQAQQSQQAQQAQQAQQAQMGMGMNNDMNFFPQNQMMRNGMMNQGMSRPNSQMGMQNNSVGSQASAANSGSAATSAPSSAPSGNNATGGRPSLTSQQMQQLSTMIKNVPIPPPLLNKIPNLPP
5) TDKAEGTNGTKAANTDNTKSPLSPNSVEWT
6) VNTWARIFELAQNKAIPPASVPAIKEIHNAHLLIVMQQHQQRLAQRRVGSTGGQNADQNINSMNNMNGMNNMNRQSQGQMNMQNQRMQQQQQQQQQQQPQQQPAFKNNKPQGGQNMQLNMGMQRPQSQQNQQQQNQQNPMMKQQNQQPQQQLQQQNQQVQGNNNLGMANQAGGQQQAAPMKMPNFQITPQDMMDYQADALAYLSRAQQEGKIPPNLDNAGKQNFI
738
473
629
68
1031
247
1017
627
660
245
1060
471










Molecular Recognition Features






MoRF SequenceStartStop




1) AAKPAKK
2) DFDRYMYE
909
1135
915
1142