Description | "Putative mediator complex, subunit Med21" |
Sequence | MMDIISQLQEQTNKIAGLTFNTFGTLQRDSPAVKLSPNYREPPANPSDDAANFAEQPKLMSAALVQAAKQFDALVAALPLADGGEEAQLKRIAELQAENDTVGQELQRQLEAAEEELKQVRELFSQAADNCLNLKKPD |
Length | 138 |
Position | Middle |
Organism | Rosa chinensis (China rose) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Rosaceae> Rosoideae> Rosoideae incertae sedis> Rosa. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.496 |
Instability index | 54.60 |
Isoelectric point | 4.50 |
Molecular weight | 15095.76 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP19547 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 92.89| 26| 27| 72| 97| 1 --------------------------------------------------------------------------- 51- 67 (18.15/ 7.04) .........ANFAEQPKLMSAALV..QA 72- 97 (40.16/23.43) DALVAALPLADGGEEAQLKRIAEL..QA 100- 127 (34.58/19.27) DTVGQELQRQLEAAEEELKQVRELfsQA --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) AANFAEQPKLMSAALVQAAKQFDALVAALP 2) EAQLKRIAELQAENDTV 3) KLSPNYREPPA | 50 86 34 | 79 102 44 |
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