<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19513
Description |
Uncharacterized protein |
Sequence | MSERETKRLRISIEPHQEKRIYSTEPNGEELFLAEKTPSEKFAALVATIDFDQLIKSEKSQDDNNPSPLSEPKKDKPDTIQQVWPWYPVAERLSHACNELDQLIELTSLLANDKLNTANITKVNGNVILEKERDARAVEEARRRVVQQFNRDLYLKESIKKEEMSQAASILQRGKTQLADMVAIDKTFFNDLLHIRRDWLLSSRPVVSKKSQQPTGRPTGKLYVDHSFRTAGSATRLEAEVVRGPTGNVSLVFPVEYNRRLRIFTSHGDNLQRISSNVPKDDADCFSKLEFSHQSQYDSELFGMMIANASSKKIPNIEVMDNDIQIHGGKDSILTIQLRSVSPATNQTPIIAPSDRQNPACVPVQVMDIALQQLLNRHYAEASNNALRLHPILDRKNPDKFVFTTDLADVHRNTGNVLESASVLFRHQSFCREMDVILDAIVRDLPQSSVHWTSVPHPSRYQSTFKFRFGQIMETDVLIDKLVIHFGDTCGPKRISQTPSELGQFILTQVSNYVLDFIVLSASVMGVRTRRSLWSVALFHPSCITTMGLIAGDKYRLKVKVVCAVTGEGRQTRELHWNDLKGATVEDKLTQLLSETPFAISGQEKKE |
Length | 607 |
Position | Head |
Organism | Planoprotostelium fungivorum |
Kingdom | Amoebozoa |
Lineage | Eukaryota> Amoebozoa> Evosea> Variosea> Cavosteliida> Cavosteliaceae>
Planoprotostelium.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.438 |
Instability index | 47.45 |
Isoelectric point | 7.67 |
Molecular weight | 68701.34 |
Publications | PubMed=29378020
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP19513
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 72.62| 21| 38| 339| 359| 1
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339- 359 (38.44/27.60) RSVSPATNQTPIIAP.SDRQNP
377- 398 (34.18/23.69) RHYAEASNNALRLHPiLDRKNP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.01| 17| 39| 425| 442| 2
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425- 442 (26.12/28.21) FRHQSFcREMDVILDAIV
467- 483 (29.89/24.15) FRFGQI.METDVLIDKLV
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 130.30| 41| 250| 7| 47| 3
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7- 47 (69.00/35.40) KRLRI.SIEPHQEKRIYSTEPNGE.......ELFLAEKTPSEKFAALVA
259- 307 (61.30/30.82) RRLRIfTSHGDNLQRISSNVPKDDadcfsklEFSHQSQYDSELFGMMIA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 62.96| 18| 319| 231| 248| 4
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231- 248 (31.31/24.13) AGSATRLEAEVVRGPTGN
551- 568 (31.65/24.47) AGDKYRLKVKVVCAVTGE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 58.23| 15| 33| 450| 464| 7
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450- 464 (29.66/24.53) VHWTSVPHPSRYQST
484- 498 (28.57/23.32) IHFGDTCGPKRISQT
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