<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19454

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMAAICEILKGGLSQVSWFQFHPVESDLSSLPDKRIKVEQKDAATLLVISSHLQLQKEGFLSAWTNSFVGPWDPSQGLHNPDEKIKLWLFIPGRHASVVDSAQSAVSRLRVVASGLWLAPGDSEEVAAALSQALRNRIERALLGLSYMRFGDVFSRYHPPQIEESIRYCVAQKAMVTAFRLTRAQPTIEFIFAATEESIFVHAIISSKHIRTLSTGDIEKVLEHSSNNTSYLLPVIISPHGMCGKLTGCCPNDLVKQVYFSNSGKIGLPHRTSQSSVCQLRGQNCYVKVSLGCSKSRGDKPLNPNPDYIRNLPKHQSTEAYAMGRVDQKGPLDLLSVHEKTFIYPPEAVLVPVLQTSFARSSLRRFWLQNWIGPSLAGSSFFRHCDGNLDILEKSWAEFSGIHTQHCYNSSSNSNNSSISSLSSSSSDSVTTGARDLEADADSSCRQSGLSSNDQMETDCLKLGSKRPRIGMTESYGQAGTVTNAPTEDVYKSNIRSMEVNRAVITGVGNDQIGSNWDWDDDDRGIVMDIQSLLSEFGDFGDFFENDVLPFGEPPGTAESSAIMFGASDCGDVGSSPAGVMDTSDQMLLPVGLPSFDSFNPPLPLVTEEFLSKSQEVTNSAVTSGPSNQTPASSTGEFDHLMKAEALMTFAVEYGAVETPASDSSSVFRNPYLPKSRKVESSNSSQSNYKYAATPPSFPCFGGLDEKTGMPMNLKAHPGGHDSNSMLQLKKYYTHVETREERYGRRLLTHNDSNATNEMSGTSQFGNLYSIKSDKSASRKMTQGVFGGERILLSMKTVLGTEVECSMFQASMLRMRHILLSPTCPATISLSRPTESSVLNQLPDDPSTMADNLSSRYEVKKESIPFKGAGDIDGVMLDGHLNAPVGVWRTVGAPKVSKLATSSIEASPSLTHNLYNEESMLSYGQSQPLQELLDGIPLLVQQATSFVDLALDADGGDCPYSWLALQEHWRRGFCCGPSMVHAGCGGTLASCHSLDIAGVELVDPLSANIHASSVISLLHSDIKSALKSAFGSLDGPLSVTDWCRGRGQSGDVGASADGSSTESNISECRDSSSIVTLSVGEAVSPSQTSVGGSSYLKDGGKVDETCQRRLNQETSGSELEQQQSSRLRSTLFVLPSPALLVGYQDDWLKTSGNSLQLWEKAPLEPYALPKPINYSVICPDIDPLTSAAADFFQQLGIVYETCKLGTHSPQSLGNQMEIDSGKWFSSGFVLLDCPQSMKIESSNASLLGSISDFFLSLSNGWDMTCYLKSLSKALKALKIGQFLFTNQKEGISSPCLVIYVVCPFPEPTAVLKTVIESSIAVGSIILPSDRDKRSLLHSQIGKALSSSAAADEASVSNIPVVSGFSVPKVVVQIVTVDAIFRVTSPPFNELVILKEMAFTVYNKARRISRGSMNDLALSSSLSRSHSVLTPMTSIPTMWKDSVGSRIPGSSIPREGEIDSSLRGGAWENSWQTRTGGLSCDPNRNGDFFYPDEVRYMFEPLFILAESGSLEHGVSPTAFGNSTSETSKIVSDESGGGFMQAANSVGSTDPGSGSQHVGLEPDGLDSSNQKIPSLHCCYGWTEDWRWLVCIWTDARGELLDCNIFPFGGISSRQDTKGLQCLFVQVLQQGCQILQACTSSDTGIVKPRDFVITRIGSFYELEYLEWQKAIYSVGGSEVKKWPLQLRRSVPDGMPANTNGTSLDQQEMSLIQERTLPSSPSPLYSSHTKASFMKGGLGQPAARKQLLSGQTSVDNSRGLLQWVQSISFVSVSVDHSLHLVLQADSPSSGTHSGTGPGQSSYIEGFTPVKSLGSTSASYMLIPSPSMRFLPPTPLQLPTCLTAESPPLAHLLHSKGSAIPLSTGFVVSKAVPSTRKDYRNHPKEEWPSVLSVSLIDYYGGNKVTQDKVIRGIAKQAGRTPSSESRDSEIDNHLILASIAAELHALSWMTVSPGFLDRRTALPFHTDMVLRLRRLLHFAEKELSGQPDKSQV
Length1986
PositionKinase
OrganismGossypium barbadense (Sea-island cotton) (Egyptian cotton)
KingdomViridiplantae
Lineage
Aromaticity0.07
Grand average of hydropathy-0.237
Instability index50.03
Isoelectric point5.68
Molecular weight215291.11
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19454
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.50|      16|      63|    1033|    1049|       1
---------------------------------------------------------------------------
 1033- 1048 (33.60/20.58)	DGPLSVTDWCRGRGQS
 1780- 1795 (31.90/13.68)	DSPSSGTHSGTGPGQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.00|      16|     394|     149|     164|       2
---------------------------------------------------------------------------
  149-  164 (32.66/17.97)	FGDVFSR.....YHPPQIEES
  539-  559 (26.33/13.00)	FGDFFENdvlpfGEPPGTAES
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     626.81|     276|     511|     785|    1208|       3
---------------------------------------------------------------------------
  827-  991 (127.38/185.14)	..................................................................................................................................................................................................................................................................................................................................................................................................ISLSRPTESSVLNQLPDDPSTMADNLSSRyeVKKESIPFKgaGDIDGvMLDGhlnapvGVWRTVGAPKVSKLATSSIEAS....PSLTHNLYneESMLSYGQSQPLQElldGI.PLLVQQATSFVD.LALDADGGdcpyswlalqehwrrGFCCGPSMVHAGCGGTlASCH
 1051- 1208 (170.26/108.38)	VGASADG..SSTESNIS.EC........RDSSSIVTLSVGEAVSPSQTSVGGSSYLKDGGKVDETCQRRLNQetsGSELEQQQSSrlRSTLFVLPSPALL..VG..YQDDWLKtsgnslqlWEKAPL.....EPYALPKPINYSVicPDIDPLTSAAADFFQQ.LGIVYETCKLGTHSP..........................................................................................................................................................................................................................................................................................................................................................................................
 1416- 1554 (161.71/57.75)	...................................................................................................................................................................................qslgnqmeidsgkwfssgfvlldcpqsmkiessnasllgsisdfflslsngwdmtcylkslskalkalkigqflftnqkegisspclviyvvcpfpeptavlktviessiavgsiilpsdrdkrsllhsqigkalsssaaadeasvsnipvvsgfsvpkvvvqivtvdaifrvtsppfnelvilkemaftvynkarrisrgsmndlaLSSSLSRSHSVLTPMTSIPTMWKDSVGSR..IPGSSIPRE..GEIDS.SLRG......GAWENSWQTRTGGLSCDPNRNGdffyPDEVRYMF..EPLFILAESGSLEH...GVsPTAFGNSTSETSkIVSDESGG...............GFMQAANSVGSTDPGS.GSQH
 1555- 1718 (167.46/57.16)	VGLEPDGldSSNQKIPSlHCcygwtedwRWLVCIWTDARGELLDCNIFPFGGISSRQDTKGLQCLFVQVLQQ...GCQILQACTS..SDTGIVKPRDFVItrIGsfYELEYLE........WQKAIYsvggsEVKKWPLQLRRSV..PDGMPANTNGTSLDQQeMSLIQERTLPSSPSP..........................................................................................................................................................................................................................................................................................................................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     208.99|      54|     510|    1283|    1358|       4
---------------------------------------------------------------------------
 1232- 1272 (39.76/11.26)	...................CP.....QSMK..IESSNAslLGSIsdfflSLSNGWDMTCYLKS.LSKA
 1283- 1342 (84.84/50.59)	FTNQKE.GISSPClviYVVCPFPeptAVLKTVIESSIA..VGSI.....ILPSDRDKRSLLHSQIGKA
 1801- 1853 (84.38/35.58)	FTPVKSlGSTSAS...YMLIPSP....SMRFLPPTPLQ..LPTC.....LTAESPPLAHLLHSK.GSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.09|      27|      29|     408|     434|       5
---------------------------------------------------------------------------
  408-  434 (41.82/18.77)	NSSSNSNNSSISSLSSSSSDSVTTGAR
  439-  465 (46.27/21.55)	DADSSCRQSGLSSNDQMETDCLKLGSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.91|      26|      27|     608|     633|       7
---------------------------------------------------------------------------
  608-  633 (42.81/23.26)	EF..LSKSQEVTNSAVTSGPSNQTPASS
  636-  663 (33.67/16.65)	EFdhLMKAEALMTFAVEYGAVETPASDS
  675-  696 (23.43/ 9.24)	.....SRKVESSNSSQSNYKYAATPPS.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.82|      13|      30|     713|     725|      12
---------------------------------------------------------------------------
  713-  725 (24.34/13.94)	LKAHPGGHDSNSM
  746-  758 (22.48/12.29)	LLTHNDSNATNEM
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19454 with Med13 domain of Kingdom Viridiplantae
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