<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19428

Description Mediator of RNA polymerase II transcription subunit 14
SequenceMAELGQQTVDFSSLVSRTAEESFTSLKELVEKSKSSDQSDTEKKINLLKYIVKTQQRMLRLNVLAKWCQQVPLIQYCQQLASTLSSHDTCFTQAADSLFFMHEGLQQARAPVYDVPSAVEVLLTGSYERLPKCIEDVGMQSSLTEDQQKPALKKLDTLVRSKLLEVSLPKEISEVKVADGTALIRVDGEFKVLVTLGYRGHLSLWRILHLELLVGERSGLVKLEQMRRHVLGDDLERRMSTAENPFATLYSVLHELCVALVMDTVIRQVQALRLGRWKDAIRFELISDGGSGGSSQLNQDNDSDSAAQRTPGLKLVYWLDFDKNSGASDTGSCPYIKIEPGPDLQIKCQHSTFVIDPLTGKEASFFLDQSCIDVEKLLLRAISCNRYTRLLEIQKELMKNVHIFRDANDVVLLSQSDEPDSEHRKEDAKLDNKEHEGQELLRVRAYGSSYFTLGINIRNGRFLLQSSQNILSSSALLECEETLNQGTMTAVDVFSSLRSKSIIHLFAAIGRFLGLEVYEHGFAAVKVPKNLVNGSSVLIMGFPESESSYFLLMELDKDFKPLFKLLETQPDPSGKGHSFNDLNNVLRIKKIDINQMQMLEDETNLSILDWRKLLPSLPNVGGPDQISEHDVLNLDGSMQVPGGPSSSFSSIVDEVFEIEKGTSATQFPSQKISSFSSSPAPHLTSVPMNLHSVKAGTPSPKWEAGLQVSQHNNVAKPSGSASHYDGSLYPSSGLKGSYNSASFGSFSSGTGRSTSAKKLSASKSEQDLASLRSPHSVDNGVLDEDQLRLPNDTSKDTLSASRSSRLLSPPRPTLPRVIAQNAKPNGPRSSSAGNLTAAVRFSGSSPLASPPPKQQKLKFAMALLMMLPNMTKIHESQPTSQVLKSSEIISKSETYSYGNLIAEANKGNVPSGIYVSALLHVVRHSSLCIKHAKLTSQMEELDIPYVEEVGLRNASSNIWFRLPCSQGDSWQHICLRLGRPGSMYWDVKINDQHFRDLWELQKGSTSTPWGSGIRIANTSHVDSHIRYDPDGVVLSYQSVEADSIKKLVADIRRLSNARTFALGMWKLLGVRADDKPEEGNANSDVKAPAGGKGPTEAVS
Length1099
PositionTail
OrganismGossypium barbadense (Sea-island cotton) (Egyptian cotton)
KingdomViridiplantae
Lineage
Aromaticity0.06
Grand average of hydropathy-0.334
Instability index44.09
Isoelectric point6.41
Molecular weight121140.95
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19428
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.47|      27|      36|     152|     187|       2
---------------------------------------------------------------------------
  130-  163 (39.05/38.03)	LPKCIEDVGMQSSLTedqqkpaLKKLDTL.VRSKL
  168-  202 (34.42/31.83)	LPKEISEVKVADGTAlirvdgeFKVLVTLgYRGHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.47|      19|      35|     332|     366|       3
---------------------------------------------------------------------------
  332-  352 (31.71/55.36)	SCpyIKIEPGPDLQIKCQHST
  370-  388 (33.76/14.19)	SC..IDVEKLLLRAISCNRYT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     196.66|      60|      96|     572|     667|       4
---------------------------------------------------------------------------
  540-  624 (64.61/75.09)	.............MGFPESESSYFllmeLDKDFKpLFKLLETQPD........PSGKGHSFNDlnnvlrikkidinqmqmledetnlsilDWRKLLPSLP......NVGGPD
  625-  699 (85.99/67.75)	QISEHDvlnldgSMQVPGGPSSSF.ssiVDEVFE.IEKGTSATQF........PSQKISSFSS...........................SPAPHLTSVPmnlhsvKAGTPS
  707-  753 (46.06/15.55)	QVSQHN......NVAKPSGSASHY.....DGSLY.PSSGLKGS.YnsasfgsfSSGTGRS....................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.33|      10|      43|     801|     810|       5
---------------------------------------------------------------------------
  801-  810 (19.75/ 8.42)	SRSSRLLSPP
  842-  851 (20.58/ 9.07)	SGSSPLASPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.12|      25|      43|     263|     290|       6
---------------------------------------------------------------------------
  263-  290 (39.22/32.42)	DTVIRQVQALRLGRWKDairFEL...ISDGG
  304-  331 (39.91/24.81)	DSAAQRTPGLKLVYWLD...FDKnsgASDTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.04|      16|     533|     441|     456|      10
---------------------------------------------------------------------------
  441-  456 (29.22/18.11)	LRVRAYGSSYFTLGIN
  975-  990 (31.82/20.37)	LRLGRPGSMYWDVKIN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19428 with Med14 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GTGRSTSAKKLSASKSEQDLASLRSPHSVDNGVLDEDQLRLPNDTSKDTLSASRSSRLLSPPRPTLPRVIAQNAKPNGPRSSSAGNLTA
2) LTSVPMNLHSVKAGTPSPKWEAGLQVSQHNNVAKPSGSASHYDGSLYPS
749
683
837
731










Molecular Recognition Features






MoRF SequenceStartStop




NANANA