<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19402

Description WW domain containing protein
SequenceMENSSQSSTAQPFRPPAVVSLGSQNFGSLSVQFRPMIPNQQGQPFLQSASQQFQPIGQGIPPNVGMPSGQSQPLHFSQPMQPYHPRPGQAVHAMPSSQGLSMSYIQTRPIAPGPPQSQQPAPPFTNQMPGSAGMPFPSAYSFAPSSFLQPQNTANSLSQFQPMSQMQAPVAPIAGQPWLPSGSQSAPALTPVQQAAQQPSAPPSTDTAINSLTQQSSSDWQEHTSNDGRRYYYNKRTKQSVWDKPLELMTPMERADASTVWKEYSSPDGRKYYYNKVTKQSKWTIPEELKLARELAEKEASQGMQLDTGLTSHGSAAVASAETPPAVTSVASGTPSVPTGVALSPVAVTPVASLPNPSFVTIPGSSATPTSQSAVTSVVGIQPPAVTVASLNPAILGSAGVSSVLTNANTPPISTYENRASQDILNSVDGASMQDIEEAKKGMAVAGKINVTPMEEKSVDEEPLVYASKLEAKNAFKSLLESANVQSDWTWEQAMREIINDKRYGALRTLGERKQAFNEYLGQRKKLEAEERRMRQKKAREEFTKMLEESKELTSSTRWSKAVTMFENDERFKAVERARDKEDLFESYIVELERKEKEKAAEEHRQNVAEYRKFLESCDFIKVNSQWRKVQDRLEDDERYLRLEKLDRLLIFQDYIRDLEKEEEEQKKIQKEHLRRVERKNRDEFRKLMEEHIAAGTLTARTHWRDYCLKVKDFPQYQAVASNTSGSTPKELFEDVIEELEKQYHEDKARVKDALKLGKVSIASTWTFDDFKAAILEDIGSPPVSDLNLKLVYEDLLERAKEKEEKEAKKRQRLADDFTKLLYTFKEITLTSNWEDCKQLFEDSQEYRSIGEESLIREVFEEYITHLHEKAKEKERKREEEKARKEREREEKEKRKEKERKEKDREREKEKGKERSKKDDTDSENIDITDSHGHKEDKKREKDKDRKHRKRHQSVTDDMGSDKDEKEESKKRKHSSDRKKSRKHAYSPESDSENRHKKHRREHRDSRRNGHDELEDGELGEDGEIP
Length1026
PositionUnknown
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.07
Grand average of hydropathy-1.048
Instability index54.72
Isoelectric point6.42
Molecular weight116868.96
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP19402
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.36|      38|      38|     219|     256|       1
---------------------------------------------------------------------------
  219-  256 (77.61/44.15)	DWQEHTSNDGRRYYYNKRTKQSVWDKPLELMTPMERAD
  260-  297 (73.75/41.61)	VWKEYSSPDGRKYYYNKVTKQSKWTIPEELKLARELAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     169.86|      28|      28|     866|     893|       2
---------------------------------------------------------------------------
  524-  545 (27.82/10.61)	RKKLE.AE.ERRM..RQKKAR.E...EF....T.........K
  840-  866 (30.65/12.42)	LFEDS.QEY.RSI..GEESLIREVFEEY...IT.........H
  867-  894 (42.65/20.10)	LHEKA.KEKERKR..EEEKARKEREREE...KE.........K
  895-  932 (24.47/ 8.47)	RKEKErKEKDRER..EKEKGKERSKKDD...TDseniditdsH
  933-  962 (22.49/ 7.20)	GHKED.K....KR..EKDKDRKHRKRHQsvtDD......mgsD
  963-  989 (21.79/ 6.75)	KDEKE.ESKKRKHssDRKKSRKHAYSPE...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     340.20|      59|      66|     546|     604|       3
---------------------------------------------------------------------------
  456-  497 (52.41/31.48)	.............EKSVDEEPLV..YASKLEAKNAF..KS..........................L....LE....SANVQSDWTWE....Q...A..MRE
  500-  567 (59.64/36.96)	NDKRYGAL.....RTLGERKQAFNEY...L............GQrkkleaeerrmrqkkareeftkM....LEE...SKELTSSTRWS....K...AVTMFE
  568-  635 (82.68/54.46)	NDERFKAV.....ERARDKEDLFESYIVELERKEKE..KAAEEH.............rqnvaeyrkF....LES...CDFIKVNSQWR....K...VQDRLE
  636-  714 (55.23/33.61)	DDERYLRL.....EKL.DRLLIFQDYIRDLEKEEEEqkKIQKEH........lrrverknrdefrkL....MEEhiaAGTLTARTHWR....DyclKVKDF.
  715-  778 (50.40/29.95)	..PQYQAV..asnTSGSTPKELFEDVIEELEKQYHE..DKAR.........................vkdaLKL...GKVSIAST.WTfddfK...AAILED
  785-  834 (39.83/21.92)	SDLNLKLVyedllERAKEKE........EKEAKKRQ..RLADDF....................tkL....LYT...FKEITLTSNW...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     218.31|      31|      58|     311|     341|       4
---------------------------------------------------------------------------
  116-  142 (39.55/24.28)	QSQQP....A.PPF.TNqmPGS.......A..............GMPFPSAYSF
  143-  173 (20.13/ 7.91)	A...PssflQ.PQNTAN................slsqfqpmS..QMQAP.VAPI
  174-  192 (36.72/21.89)	A.GQP....WLP.......SGS.......Q................SAPALTPV
  300-  330 (49.05/32.30)	ASQGM....QLDTGLTS..HGS.......AAVA........S..AETPPAVTSV
  331-  351 (35.00/20.45)	ASGTP....SVPTGVAL.............................SPVAVTPV
  352-  388 (37.84/22.84)	AS.LP....N.PSFVTI..PGSsatptsqSAVT........SvvGIQPPAVT.V
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     109.21|      17|      18|      26|      42|       5
---------------------------------------------------------------------------
   26-   42 (31.87/19.87)	F.GSLSVQFRPMIPNQQG
   45-   59 (21.49/10.70)	FlQSASQQFQPI...GQG
   64-   80 (28.18/16.62)	V.GMPSGQSQPLHFSQPM
   83-   99 (27.68/16.17)	Y.HPRPGQAVHAMPSSQG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19402 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KAKEKERKREEEKARKEREREEKEKRKEKERKEKDREREKEKGKERSKKDDTDSENIDITDSHGHKEDKKREKDKDRKHRKRHQSVTDDMGSDKDEKEESKKRKHSSDRKKSRKHAYSPESDSENRHKKHRREHRDSRRNGHDELEDGELGEDGEIP
2) LSVQFRPMIPNQQGQPFLQSASQQFQPIGQGIPPNVGMPSGQSQPLHFSQPMQPYHPRPGQAVHAMPSSQGLSMSYIQTRPIAPGPPQSQQPAPPFTNQMPGSAGMPFPSAYSFAPSSFL
3) PEELKLARELAEKEASQGMQLDTGLTSHGSAAVASAETPPAVTSVASGTP
4) PQNTANSLSQFQPMSQMQAPVAPIAGQPWLPSGSQSAPALTPVQQAAQQPSAPPSTDTAINSLTQQSSSDWQEHTSNDGRRYYYN
870
29
286
150
1026
148
335
234










Molecular Recognition Features






MoRF SequenceStartStop




1) DRKKSRKHAYS
2) GRKYYYNK
3) HDELEDGELGE
4) RHKKHRR
977
269
1011
995
987
276
1021
1001