<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19401

Description Mediator of RNA polymerase II transcription subunit
SequenceMAVYVQTSLCDSVMELTKVAQQKGSDPLLWAIQLSSNLSSAGVSLPSVEVANSLVSYICWENNVPIMWKFLEKALVLKIVPPMLVLALLSTRVIPSRGSQPVAYRLYMELVKRHVFNLKSQINGPNCEMVMKSIDDVLHLSTKFGLLASEPGIVVVEFIFSMAWQLLDASLDDEGLLNHTHTLEQNSIWATTPQEMEIDGHCSYEEKWTEHNEILKNANTVMAIEIIGELLRNKVTSRILFLARRHLPTHWTSFIQRFQMLGENSSALRNSKTLSPEALLQLVADTRIVLSRECKTSSLHKFHAVMAFGSLASSTGLCHGASRSALWLPLDLVLEDAMDGYQVDATSAVERITGLIKTLQAINGTTWHDTFLGLWIAALRLIQRERDPIEGPVPHLDSRLSILLCITTLVVADLIEEEEGAPLEETECGSTNQWKEKKEASGKRRNDLVSSLQMLGDYQGLLAPPQSVVPVANQAAAKAMFFLSGIGVGNAYFECLSVKDMPINCSGNMRHLIVEACIARNLLDTSAYFWPGYVNGCVNQMPQGVPAQVPSWSSFMKGATLSPLMINSLVSSPASSLAELEKIFEIAINGSNDERISAATILCGASLIRGWNIQEHTAHFIIRLLSPPVPVDYAGVDSHLIGYAPMLNVLIVGIASVDCVQIFSLLGLVPQLACSLMPICEVFGSCVPNISWTLTSGEEISAHAVFSNAFILLLKLWRFNHPPLEHGVGDVPTVGSQLTPEYLLAVRNSYLVSSGNAFQDQNKRRLSAVASSSSPQPVFVDSFPKLKAWYRQHQACIASTLSGLVHGTPVHQIFDGLLNMMFRKIGRGSQSLTSATSGSSSSSGPGIEDNSLRPKLPAWDILEAVPFVVDAALTACAHGTLFPRELATGLKGLADFLPASLAGIVSYFSAEVTRGIWKPAFMNGTDWPSPAANLSNVEEQIKKILAATGVDVPSLAAGGSSPATLPLPLAAFVSLTITYKIDKASERFLNLAGPALESLAAGCPWPCMPIVASLWTQKAKRWTDFLVFSASRTVFLHNSDAVVQLLKSCFTAALGLNAIPISSNGGVGTLLGHGFGSHFCGGMSPVAPGILYLRVFRSMRDIVFTTEEIVAILMHSVREIACSSLPRRKLEKLKTAKKNGVRYGQVSLAAAMTRVKLAASLGASLVWLTGGLFLVQSLIKETLPSWFISKHRSEHEEGSSEGMVAMLGGYALAYFAVLCGAFAWGVDSSSAASKRRPKVLGTHMEFLASALDGKISLGCDGATWRAYVLGFVSLMVGCTPNWVLEMDVDVLKRLSNGLKQWNEVELALALLGVGTMGAAAELIVENEM
Length1328
PositionTail
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.08
Grand average of hydropathy0.231
Instability index43.41
Isoelectric point6.30
Molecular weight143832.95
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19401
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     166.74|      53|     638|     320|     375|       1
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  320-  375 (86.20/72.14)	GASRSALWLPLDLVLEDAMdGYQVDATSavERITGLI.KTLQAI.NGTTWH..DTFLGLW
  959- 1015 (80.54/56.13)	GSSPATLPLPLAAFVSLTI.TYKIDKAS..ERFLNLAgPALESLaAGCPWPcmPIVASLW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     290.62|      88|     589|     601|     694|       2
---------------------------------------------------------------------------
  512-  587 (120.14/52.46)	...........LIVEACIA....R..NLLDT...SAYFWPGY....VNGCVNQMPQGV.PAQV....PSWSSFMKG.ATLSPLMINSLVSSPASSLAELEKIFEIA
  590-  683 (139.80/70.05)	GSNDERISaatILCGASLI....RGWNIQEH...TAHFIIRL....LSPPVPVDYAGV.DSHLIGyaPMLNVLIVGiASVDCVQIFSLLGLVPQLACSLMPICEVF
  684-  735 (30.68/12.52)	GSCVPNIS...........wtltSGEEISAHavfSNAFILLLklwrFNHP.PLEH.GVgDVPTVG.........................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.36|      29|     790|     428|     463|       4
---------------------------------------------------------------------------
  428-  463 (38.43/46.37)	CGSTNqWK.EKKEASGKRRNdLVsslqmLGDYQGLLA
 1219- 1248 (49.93/33.16)	CGAFA.WGvDSSSAASKRRP.KV.....LGTHMEFLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.77|      24|     934|     240|     266|       7
---------------------------------------------------------------------------
  240-  266 (36.78/27.64)	LFLA....RRHLPThWtsFIQRFQMLGENSS
 1172- 1199 (38.98/19.25)	LFLVqsliKETLPS.W..FISKHRSEHEEGS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19401 with Med33 domain of Kingdom Viridiplantae
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