<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19394

Description Mediator of RNA polymerase II transcription subunit
SequenceMNQVAVPKEPEEDESAAQSIELSQGSDKADSAGGGGGGAGAVEEEDAVEKPHDPMEEDAVSPATVFCIRLKQPRSNLLHKMSVPELCRNFSAVAWCGKLNAIACASETCARIPSSNANPPFWIPIHIVIPERPTECAVFNVVADSPRDSVQFIEWSPTSCPRALLIANFHGRITIWTQPSQGSANVVRDATCWQREHEWRQDIAVVTKWLSGVSPYRWLSSKSSSGSNSKSTFEEKFLSQQSQNSARWPNFLCVCSVFSSGSVQLHWSQWPPNQNSASAKWFCTSKGLLGAGPSGIMAADAIITDSGAMHVAGVPIVNPSTVVVWEVTPGPGNGFQTTPKTSTSNGVPPSINPPSWAGFSPLAAYLFSWQEYLISEAKSGKKQTDLEFGDTVQLHCSPVSNFSAYVSPEAAAQSATTTTWGSGVTAVAFDPTRGGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSVQPVVLHQIFGNPTSSFGGQAPMQTVWVSKVDTSIQPTNDFKSHQTTATGVTGPTSDVRKASDSIVEKAKRVNFDPFDLPSDVRTLARIVYSAHGGEIAVAFLRGGVHIFSGPNFAPVDNYQINVGSAIAAPAFSSTSCCSASVWHDTSKDRTILKIIRVLPPAVPGSQDKANSSAWERAIAERFWWSLMVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSTQHRQQYGPSLDRIKCRLLEGTNAQEVRAMVLDMQARLLLDMLGKGIESALINPSALVPEPWQASGETLSGIDPEAMAVEPSLVPSIQAYVDAVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNMVASPTQSSASPATNQGGQSGTTNSTGSTQMQAWVQGAIAKISSTTDGVSSSAPNPISGPSSFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRFTGASQRNTDTSVQKPQSGPPGKVEEMGSAPTKPLSVVRTDENQVARAGQVMPGAKAVEEGSSGRSRLGSGNAGQGYTFEEVRVLFLILMDLCRRTSGLAHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMYGGPWSDPDDMGSLDDTPKLSNSADPLDFSSLESCDVYYGTQGLWPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTAVWKTGLEGVWYKCIRCLRQTSALASPSATNPPNQNDREVWWISRWAYGCPMCGGTWVRVV
Length1250
PositionTail
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.08
Grand average of hydropathy-0.221
Instability index43.99
Isoelectric point5.99
Molecular weight134626.88
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19394
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.24|      32|      94|     423|     458|       1
---------------------------------------------------------------------------
  423-  458 (52.96/47.07)	GVTAvafdPTRGGSVIAVVIVEGQYMSPYDPDEGPS
  520-  551 (56.29/38.92)	GVTG....PTSDVRKASDSIVEKAKRVNFDPFDLPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.78|      17|      17|     786|     802|       2
---------------------------------------------------------------------------
  786-  802 (28.66/19.98)	IQAYVDAVLDLASHFIT
  804-  820 (30.12/21.38)	LRRYASFCRTLASHAVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.74|      27|     533|     579|     622|       3
---------------------------------------------------------------------------
  581-  610 (46.11/41.18)	SGP.NFAPVdnyQINVGSAIAAPAFSSTSCC
  886-  913 (48.63/13.06)	SGPsSFMPI...SINTGTFPGTPAVRLIGDC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.61|      23|     533|     649|     671|       4
---------------------------------------------------------------------------
  649-  671 (47.76/27.32)	RAIAERFWWSLMVGVDWWDAVGC
 1185- 1206 (41.53/22.78)	RDVVTAVWKTGLEGV.WYKCIRC
 1227- 1239 (30.32/14.63)	REV....WW.....ISRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.19|      10|      18|     751|     760|       5
---------------------------------------------------------------------------
  751-  760 (19.16/10.59)	INPSALVPEP
  771-  780 (19.03/10.46)	IDPEAMAVEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.02|      30|     949|       7|      44|       6
---------------------------------------------------------------------------
   15-   44 (50.91/35.61)	SAAQSIELS...QGSDKADSAGGGGGGAGAVEE
  964-  996 (46.11/17.86)	GSAPTKPLSvvrTDENQVARAGQVMPGAKAVEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.77|      17|      18|     700|     717|       8
---------------------------------------------------------------------------
  700-  717 (27.05/21.83)	TQHRQQYGPSLDrIKCRL
  721-  737 (27.72/16.97)	TNAQEVRAMVLD.MQARL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.12|      10|      16|     167|     176|       9
---------------------------------------------------------------------------
  167-  176 (20.30/12.83)	ANFHGRITIW
  184-  193 (19.82/12.34)	ANVVRDATCW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.47|      13|      32|     460|     473|      10
---------------------------------------------------------------------------
  460-  473 (22.89/14.33)	TGWrVQRWESSVQP
  495-  507 (24.58/11.06)	TVW.VSKVDTSIQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.98|      33|     433|     389|     422|      11
---------------------------------------------------------------------------
  389-  422 (53.94/36.91)	GDTVQLHCSPVSNfSAYVSPEAAAQSATTTTWGS
  824-  856 (56.04/33.25)	GSNRNMVASPTQS.SASPATNQGGQSGTTNSTGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     169.47|      44|     232|      75|     122|      12
---------------------------------------------------------------------------
   75-  119 (76.71/38.86)	SNLLHKMSVPeLCRNFSAVAWC...GKLNAIACASETCAR..IPSSNANP
  306-  353 (67.38/29.74)	SGAMHVAGVP.IVNPSTVVVWEvtpGPGNGFQTTPKTSTSngVPPS.INP
  861-  884 (25.37/ 6.90)	...................AWV..qG...AIAKISSTTDG..VSSSAPNP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19394 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GTGSNRNMVASPTQSSASPATNQGGQSGTTNSTGSTQ
2) MNQVAVPKEPEEDESAAQSIELSQGSDKADSAGGGGGGAGAVEEEDAVEKPHDPME
3) TGASQRNTDTSVQKPQSGPPGKVEEMGSAPTKPLSVVRTDENQ
822
1
938
858
56
980










Molecular Recognition Features






MoRF SequenceStartStop




1) MNQVAVPKEPEEDESAAQSIELSQGS
1
26