<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19391

Description Mediator of RNA polymerase II transcription subunit
SequenceMAAMEGVIQNQIQQPQPQQQQQQQPQPQPQPVVVERLNDAVQQQLNLESVKTRALSLFKAISRILEDFDVYARTNTTPKLQDILQQYSMVNLELFNIVDEIKKVSKAFVVHPRNVNADNSTILPVMLSSKLLPEMETDDNLKKDQLLHGMQNLPVSSQIEKLKARIDMIGAACESAEKVLADTRKAYCFGTRQGPPIVPTLDKAQAAKIQEQENLLRAAVNYGEGLRLPGDQRQVTPTLPVHLADVLTTGDGMQTFYDSSGMYHKNTPTSSNNLAAQSPLLQAPGSQLLGRSAASPGTVTVTNFDSTTTSPLPYANSPRSSTSMMNTPSPQQQSQQQQQQQQQQQQQQQQQQQQQQQQQQRQKLMQLPQHQQQQLLAQQQFRQSAMQGLGQNQLALHDLQGQTQQKFQSLHGQHQMQFSQPMGHQQFQGRQLPSGHVQHGIGQSQLNQGSQINRLSQFSSAANSALFNAAQTTANPQMIPNMSATMSSPSLLPRMQFGLSGNNPQRSHATQILSDQMFNMGAGNPGAMMPIQQQQQQQQQQQQHNTQGAFGSMAQNAQNLQSGMAALQSNPQNHPNFSQQRQQNQQ
Length586
PositionHead
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.04
Grand average of hydropathy-0.803
Instability index66.95
Isoelectric point9.11
Molecular weight65129.07
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19391
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.95|      15|      15|     331|     345|       1
---------------------------------------------------------------------------
  331-  345 (33.22/ 7.39)	QQQSQQQQQQQQQQQ
  348-  362 (31.73/ 6.71)	QQQQQQQQQQQQQRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.14|      28|     513|      12|      49|       2
---------------------------------------------------------------------------
  382-  427 (34.85/ 9.08)	RQSAMQGlG...QNQLALHDlqgqtqqkfqslhgqhqMQFSQPMGHQQF
  544-  586 (34.29/ 7.75)	HNTQGAF.GsmaQNAQNLQS.....gmaalqsnpqnhPNFSQQRQQNQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.33|      13|     513|      12|      24|       3
---------------------------------------------------------------------------
   12-   24 (29.10/ 8.12)	IQQPQPQQQQQQQ
  531-  543 (27.23/ 7.09)	IQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.43|      30|      32|     267|     296|       4
---------------------------------------------------------------------------
  236-  264 (42.53/20.47)	TPTLPV.HLA..DVLTTG..DGMQTFyDSSGMYH
  267-  296 (50.46/25.58)	TPTSSN.NLAAQSPLLQA..PGSQLL.GRSAASP
  298-  330 (41.44/19.77)	TVTVTNfDSTTTSPLPYAnsPRSSTS.MMNTPSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.45|      31|      41|     450|     484|       5
---------------------------------------------------------------------------
  450-  479 (32.57/24.52)	.........SQINRLsQFSSAANSALFNAAqtTANP.QMI
  481-  505 (26.73/12.87)	NMSAtmsspSLLPRM.QFGLSG.....N......NP.Q..
  506-  529 (38.15/15.68)	RSHA.....TQI.........LSDQMFNMG..AGNPgAMM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.83|      33|      41|      36|      75|       6
---------------------------------------------------------------------------
   36-   73 (47.64/57.15)	RLNDAVQQ..QLNLEsvktrALSLFKAISRILEDFDVYAR
   79-  113 (50.19/36.74)	KLQDILQQysMVNLE.....LFNIVDEIKKVSKAFVVHPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.46|      18|      32|     184|     205|       8
---------------------------------------------------------------------------
  184-  205 (22.42/22.64)	RKAYCFGtrQGPPIvPTlDKAQ
  217-  234 (33.04/16.23)	RAAVNYG..EGLRL.PG.DQRQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19391 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MQGLGQNQLALHDLQGQTQQKFQSLHGQHQMQFSQPMGHQQFQGRQLPSGHVQHGIGQSQLNQGSQINRL
2) NSALFNAAQTTANPQMIPNMSATMSSPSLLPRMQFGLSGNNPQRSHATQILSDQMFNMGAGNPGAMMPIQQQQQQQQQQQQHNTQGAFGSMAQNAQNLQSGMAALQSNPQNHPNFSQQRQQNQQ
3) QTFYDSSGMYHKNTPTSSNNLAAQSPLLQAPGSQLLGRSAASPGTVTVTNFDSTTTSPLPYANSPRSSTSMMNTPSPQQQSQQQQQQQQQQQQQQQQQQQQQQQQQQRQKLMQLPQHQQQQLLAQQQFRQS
386
463
254
455
586
384










Molecular Recognition Features






MoRF SequenceStartStop




NANANA