<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19382

Description "Mediator complex, subunit Med"
SequenceMQRYHATGCTSAVNNSSIGGASGRDTARADSASLPANYPLNSRRPSLLSPYKLKCDKEPLNSRLGPPDFHPQIPNCPEETLTKEYVQSGYRETVEGLEEAREITLTQVQSFSKPVVVKCKESIRKCLRAINESRAQKRKAGQVYGVPLADSLLTKPGVFPEQRPCSEDFRKKWIEGLSQQHKRLRSLADHVPHGYRKRYLFDVLIRNNVPLLRATWFIKVTYLNQIRPSSGSISGASDKAQLSRSELWTRDVIDYLQTLLDEFFSKNNSHSTSHNRDRSPQMLYAGSVHQKADPVSAASDIEDSSLHFKWWYMVRLLQWHHAEGLILPSSVIDWVLRQLQDKELLEILQLLLPIIYGVLETVVLSQTYVRSLVGIAVQFIREPSPGGSDLVDNSRKAYTTSALVEMLRYLIVAVPDTFVALDCFPLPSCVVSHVVTDGSLSKSSSEDVRKIKIGSSEVSSLFRSKGLDAQYQSLALNYVVSSIQKRADNLAKAARPGYPGHSVAKVAEALDRSLVQGDVRGAYKLLFEDLCEGVVSEHWISEVSPCLRSLLKWIGTVSLSFVCSVFLLCEWATCDFRDFRTAPPDELKFTGRKDFSEVYVAIRLLKLKIGGLQNVPRTKSDNPFGGNILKKCSSQQNSFSVKTTMRGLHEFKSNSKFVDHSMKVSSIFESPGPLHDIIVCWIDQHEACKGEGFQRLQLLIVELIHAGIFYPQAYVRQLMVSGIMEMNGSVIEAERRKRHYRILKHLPGLFVRDALEEAGFAEGPELLEAMQVYSNERRLVLSGLLCNLSKQVNKTKISARKQKFYPVSGKDGASSASVDQWKPIQPSNVVSGRNVKNDVDIEELKEAISVLLQLPSTSLKSTDAGLDEMQVGMKRSSVSLFNKMDMGEGTPGCEECKRVKRQKLGEERSSCLQGHSPTLSDDEDTWWVKKGSKSSDSLKVDLPLKSNKQVSRNRQKVPRKTQSLAQLAASRIEGSLGASTSHVCDNKVSCPHHRTGMEGEIPKSAEGVKTNNCTDVVSIGKALKRLRFVEKRTVSVWLVTVIRQVVEESEKTIAKVGQPGRPFTSVDDRNGVRWKLGEDELSTIMYLMDVSNDLVLAVKFVLWLLPKVLGSPNSTIHGGRSSLLLPRNVESQVCEVGEAFLVSSIRRYENILIAQDLIPEALSAAMHRAATVMASNGRVSGSSVLVYARYLLRRYGNVASVVEWEKTFKATSDKRLVSELESGRSTDGELNFPLGVPAGVEDLDDFFRQKMSGGRLSRVGANMRDIVQRNLNAEDVLQHFFGKERKVFAAGTPKGPAAEKLDDGYQVAQRIISDLMDCIRQTGGAAQEGDPSLVSSAVSAIVGNVGPTIAKLPDFRVGSGYPNGPSATDSLNIARRILRIHISCLCLLKEALGERQTRVFEVALATEASSALAAVFTPGKASRNQFQSSPESHDSNSSMSNENLNNSTKVVLSRTTKFAAAVSALIIGAVVHGVTNLERMVTVLRLKDGLDIVQFIRSTRSSSNGSARSMGAFKMDNFMEVYVHWFRLLVGNCRTVSDGLIVELLGEPSIVALSRMQSMLPVILVFPPAYSIFAFVIWRPFILSSSLSVREDINQLYQSLTLAINDAIKHLPFRDACLRDGQGFYDLVAADGSDAEFGAMLELGGSDLHLKSKAFVPLRARLFLNAIIDCKMPEDGNRVSGHGESKTQLAETETKLLDNIVHVLDTLQPAKFRWQWIELRLLLNEQTLVEKLQTHDVSLTDAIRSSSPSPGKAAASENENNFIQIILTRLLVRPDAASLFADVVHRFGRSLEDSMLLQAKWFLGGSDVLLGRKTIRQRLINIAENEGLSTKGQFWKSWGWCNSDSHPVTTGERKKFEAISLEEGEVAEEGTDSKRYKKRSIQSLDSEGLNVTQQLVTERALIDLLLPCIDQSSDDSRKAFANDLIKQLSNIEQQINAVTRGTDKQAGSAPSGIEGPTSKGNNRKVIKGGSPGLSRRPATSSADSAPPSPAALRASMLLRLQLLLRLLPVICADGEPSGRNLRHMLASVILRLLGNRVVHEDVELSYNPIQTSLSKREVESLTEAASSDSTDLSGESLFDRLLLVLHGLLSSCQPSWLKSKPAPKSTNDYSKDVSIIDRELAETLQCDLDRMQLPDMIRWRIQTAMPVLLPSVRCFVSCQPPSIPNAALASLQSSISIPGSYSGNLITAQRSQFHLARPVANIAGKSKSLPLQDYDTEIDPWTLLEDGAGSGPSSSNSGLIGSGDHANLRASSWLKGAVRVRRKDLTYIGAVDDDS
Length2275
PositionKinase
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.06
Grand average of hydropathy-0.239
Instability index49.11
Isoelectric point8.79
Molecular weight250961.63
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19382
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     213.50|      84|     419|    1625|    1776|       1
---------------------------------------------------------------------------
 1476- 1530 (54.05/ 8.46)	NLERMVTVLRLKDgldiVQFIRSTRSSSNGSARSMGAFKMDNFMEVYVhwFRLLV........................................................................................................................................
 1625- 1662 (31.42/88.76)	.......................................................gncrtvsdglivellgepsivalsrmqsmlpvilvfppaysifafviwrpfilssslsvredinqlyqsltlaindaikhlpfrdaclrdgqgfYDLVAADGSDAEFGAMLE....LGGSDLHLKSKAfvpLRARL
 1724- 1819 (128.02/101.65)	NEQTLVEKLQTHD....VSLTDAIRSSSPSPGKAAASENENNFIQIIL..TRLLV......................................................................................rpdaaslfADVVHRFGRSLEDSMLLQakwfLGGSDVLLGRKT...IRQRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.80|      17|      18|      39|      55|       2
---------------------------------------------------------------------------
   39-   55 (33.06/22.02)	PLNSR.RPSLLSPYKLKC
   59-   76 (32.74/21.71)	PLNSRlGPPDFHPQIPNC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.24|      12|     421|    1704|    1715|       3
---------------------------------------------------------------------------
 1704- 1715 (24.10/14.56)	LDTLQ.PAKFRWQ
 2128- 2140 (21.14/11.79)	LDRMQlPDMIRWR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.31|      13|     424|     485|     502|       7
---------------------------------------------------------------------------
  490-  502 (25.34/21.45)	LAKAARPGYPGHS
 1053- 1065 (24.98/ 8.38)	IAKVGQPGRPFTS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19382 with Med12 domain of Kingdom Viridiplantae
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