<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19379

Description "Coactivator CBP, KIX domain containing protein"
SequenceMDNNNWRPVQGGEPTMDTTDWRTQLQPDSRQRIVNKIMDTLKKHLPFSGQEGLHELKKIAERFEEKIYTAATSQSDYLRKISLKMLTMETKSQNTIPNALPSNPGGNNSRPADPGSLVMQPQVLNQGQSLAMPLPPNQSQTRQQLLSQNIQNAAAVQSSSSLSSALPPPSSLGQTSIPSGVGQNANMQNIPGNSQNSVGNSMGQGVPANMYANTQRQMQGRQQVVPQQQQQSQNPQQQYLYQQQQLQQQILKPKFQQGNISQSMMQSHIQQQQQQQQQNLLQPTQLQSSQQAVVQTSSTMQPSLMQSSLPSLQQNQPSSIQQQTKPMLQQHPQSVLRQQQQPQQAAVAHQQQAQMSQQQQLMSQQPNSTNMQQSHLIAQQNNVGDLQQQQRLLGQQNNLPNLQQQQLLAQQNNLSNLHQQQLAPQSNVAGLQQQQQLLGTQTGNSGMQTNQHAVHMLQQSKAPLQQQPQQSGSNLLPTQAQQLQPQQQILSQIQSQPTQMQQQLGLQQQPNALQRDMPQRLQASGQTSGSLLQTHNVIDQQKQLYQSQRALPETSSTSVDSTAQTGHASGGDWQEEVYQKIKTMKESYLPELLEMYQKIAGKLQQLDSLPQQPKSEQLDKLKLFKSTLERAIQFLQVPKGSIGPGYKDRLAHYEKQIISFINTNRPRKPVSQLQQGQHPPSSHMHPMQQPQSQINQVQSHENQMNPQLQPINVQSSVGTMQQNNMTSLQQNSMPSLSGVSTTQQNVMNSLQPTSNVDSGQGNALNPLQQVSVGSLQQNPVTAPQQANMNALSSQNGVNVLQPNINTLQSNSNMLQHQHVKQQQEQQMLQTQQLKQQYQQRQMQQQLMQKQQILQQQQQQQQQQQQQQQQQQQQQQQQQLQQQAKQQLPAQMQTHQNQMPQLHQINDVNDLKMRQSMGVKPGVFQQHLPAGQRSAYPHQQLKSSSPFTISSNQLLQASSPQILQHSSPQVDQQNLLSTLTKAGTPLQSANSPFVVPSPSTPLAPSPMPGDSEKPAPGVSSLANAGNVGQQQTTGVVAPAQSLAIGTPGISASPLLAEFSGPEGTHANTLAAVSGKSSITEQPLDRLIKAVKSMSPKALSASVSDIGSVVSMMDRIAGSAPGNGSRAAVGEDLVAMTKCRLQVRNFMNQDATNGTRKMKRYTSAMPLNVVSSASSINDSFKQFNGSETSDLESTATSGIKRPKIEANHALIDEIREINQRLIDTVVDIIDEDVDPSVAAAAIEGGEGTIVKCSFSAVALSPNLKSQYASARMSPIQPLRLLVPTNYPNCSPILLDKFPVEVSREYEDLSVKAKSKFSISLRSLSQPMSLGAIARTWDVCARAVISEHAQQSGGGSFSSKYGTWENCLSAA
Length1368
PositionTail
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.03
Grand average of hydropathy-0.779
Instability index72.51
Isoelectric point9.40
Molecular weight150610.76
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19379
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     240.27|      37|      37|     815|     851|       1
---------------------------------------------------------------------------
  215-  256 (44.47/ 6.91)	QRQMQgrQQVVPQQQqqsqnpQ....QQYLYQQQQ......LQQQILKPKFQ
  257-  291 (47.83/ 8.13)	QGNIS..QSMMQS...............HIQQQQQQQqqnLLQPTQLQSSQQ
  368-  402 (42.48/ 6.18)	STNMQ..QSHLIAQ............QNNVGDLQQQQ...RLLGQQNNLPNL
  696-  736 (43.62/ 6.60)	QVQSH..ENQMNPQL......QpinvQSSVGTMQQNN...MTSLQQNSMPSL
  839-  875 (61.88/13.25)	QRQMQ..QQLMQKQQ....ilQ....QQQQQQQQQQQ.....QQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     520.00|      74|      74|     405|     478|       2
---------------------------------------------------------------------------
  295-  341 (62.13/13.43)	QT.SSTMQP..S......LMQSSLPSL.Q..QNQP...SS..............................................iqQQT.....................................................KP.....M......LQQH...P...QSV........LRQ........QQQ....
  342-  440 (65.28/14.64)	...P.......QQAAVAHQQQAQMSQQ.Q..Q..........LMS..QqpnstnmqqshliaqqnnvgdlqqqqrllgqqnnlpnlqqQQLL.......AQ.......................................QNNLSN.....L......HQQQLA.P...QSN.....VAGLQQ........QQQLLGT
  441-  513 (110.94/32.14)	QTGNSGMQT..NQHAVHMLQQSKAPLQ.Q..QPQQ...SGSNLLP..T......................................qaQQLQ.......PQ.......................................QQILSQ.....I......QSQPTQ.M...QQQ.....L.GLQQ........QPNAL..
  514-  568 (60.68/12.88)	.......QR..D.....MPQR....LQ.A..SGQT...SGS.LLQ..T........................................HNVI.......DQ.......................................Q.K..Q.....L......YQSQRAlP...ETS.....STSVDS........TAQTGHA
  569-  637 (59.60/12.47)	SGGDWQEEV..YQK.IKTMKES....................YLP..E...................................llemyQKIA.......GK.......................................LQQLDS.....L......PQQPKS.E...QLDklklfKSTLER........AIQFLQV
  638-  691 (63.57/13.99)	PKGSIGPGY..KDRLAHYEKQIISFINtN..RPRK...PVS........................................................................................................Q.....L......QQGQHP.P...SSH.....MHPMQQ........PQ.....
  809-  918 (52.50/ 9.75)	..SNSNMLQ..HQH....VKQ.......Q..QEQQ.......MLQ..T........................................QQLK.......QQyqqrqmqqqlmqkqqilqqqqqqqqqqqqqqqqqqqqqqQQQLQQqakqqL......PAQMQT.H...QNQ.....MPQLHQindvndlkMRQSMGV
  919- 1001 (45.30/ 6.99)	KPG......vfQQHLPAG.QRSAYPHQ.QlkSSSPftiSSNQLLQasS........................................PQILqhsspqvDQ.......................................QNLLST.....LtkagtpLQSANS.PfvvPSP.....STPL.................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     130.98|      29|      29|     129|     157|       3
---------------------------------------------------------------------------
   92-  123 (31.51/11.15)	.SQNtIPNALPSNpggNN.....SRPADPGSLVMQPQV
  124-  145 (30.15/10.24)	LNQG...........qSL.....AMPLPPNQSQTRQQL
  146-  177 (43.07/18.77)	LSQN.IQNAAAVQsssSL.....SSALPPPSSLGQTSI
  744-  772 (26.24/ 7.67)	..QN.VMNSLQPT...SNvdsgqGNALNPLQ...QVSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.18|      12|      16|     181|     193|       4
---------------------------------------------------------------------------
  181-  193 (19.09/15.39)	VGqNANMQNIPGN
  198-  209 (23.09/13.37)	VG.NSMGQGVPAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.17|      16|      16|    1271|    1286|       5
---------------------------------------------------------------------------
 1271- 1286 (29.55/19.13)	SPI..QPLRLLVPTNYPN
 1288- 1305 (23.61/13.73)	SPIllDKFPVEVSREYED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.69|      14|      15|     777|     791|       6
---------------------------------------------------------------------------
  777-  791 (21.17/14.94)	QNPVTApQQANMNAL
  794-  807 (25.52/12.71)	QNGVNV.LQPNINTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.29|      29|      29|    1025|    1053|       7
---------------------------------------------------------------------------
 1025- 1053 (48.50/25.53)	NV.GQQQTTGVVAPAQSLAIGTPGISASPL
 1056- 1082 (34.53/16.02)	EFsGPEGTHANTLAAVS...GKSSITEQPL
 1100- 1120 (25.26/ 9.70)	SV.S..DIGSVVSMMDRIAGSAPG......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      58.65|      15|      15|    1197|    1211|       8
---------------------------------------------------------------------------
 1197- 1211 (23.65/20.35)	IKRPKIEANHALIDE
 1215- 1229 (22.12/18.48)	INQRLIDTVVDIIDE
 1235- 1247 (12.88/ 7.22)	VAAAAIEGGEGTI..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19379 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KPKFQQGNISQSMMQSHIQQQQQQQQQNLLQPTQLQSSQQAVVQTSSTMQPSLMQSSLPSLQQNQPSSIQQQTKPMLQQHPQSVLRQQQQPQQAAVAHQQQAQMSQQQQLMSQQPNSTNMQQSHLIAQQNNVGDLQQQQRLLGQQNNLPNLQQQQLLAQQ
2) KQLYQSQRALPETSSTSVDSTAQTGHASGGDWQEE
3) LTMETKSQNTIPNALPSNPGGNNSRPADPGSLVMQPQVLNQGQSLAMPLPPNQSQTRQQLLSQNIQNAA
4) MDNNNWRPVQGGEPTMDTTDWRTQLQPDSRQRIVNKIMDTL
5) NLSNLHQQQLAPQSNVAGLQQQQQLLGTQTGNSGMQTNQHAVHMLQQSKAPLQQQPQQSGSNLLPTQAQQLQ
6) NRPRKPVSQLQQGQHPPSSHMHPMQQPQSQINQVQSHENQMNPQLQPINVQSSVGTMQQNNMTSLQQNSMPSLSGVSTTQQNVMNSLQPTSNVDSGQGNALNPLQQVSVGSLQQNPVTAPQQANMNALSSQNGVNVLQPNINTLQSNSNMLQHQHVKQQQEQQML
7) PLQSANSPFVVPSPSTPLAPSPMPGDSEKPAPGVSSLANAGNVGQQQTTGVVAPAQSL
8) QMQQQLGLQQQPNALQRDMPQRLQASGQTSGSLLQTH
9) QQQQQQQQQQQQQQQQLQQQAKQQLPAQMQTHQNQMPQLHQINDVNDLKMRQSMGVKPGVFQQHLPAGQRSAYPHQQLKSSSPFTISSNQLLQASSPQILQHSSPQVDQQNLLSTLTKAG
10) VQSSSSLSSALPPPSSLGQTSIPSGVGQNANMQNIPGNSQNSVGNSMGQGVPANMYANTQRQMQGRQQVVPQQQQQSQNPQQQY
252
542
86
1
413
664
984
499
863
156
411
576
154
41
484
828
1041
535
982
239










Molecular Recognition Features






MoRF SequenceStartStop




1) YEKQIISFI
653
661