<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19369
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MNEKLQISLDKLQLKRLEAIEENGAERFPTDVGYDEKRLSLIRRIDFAWAVEKDDKKKQKKSAKESSTPWPWQSMVENLQLAQQELSVILDLINTVEANDAVTVASMTRPKPLPNEVLSDLAVSAATKLQCFRSLGKYFKQSAKALEQQVSREARFYGALIRLQQNWKVKRQRVAAPSSGNEGFTIDLFDNLLYDPASVYRPSSLSMVRVDHDPAGMLAINLPPSSCRSLQFGFFGTHPCDSTETSYIKVRSSDQHNSRESEKDAGSDDECIIKEMHLLLRQVHQTIFDEQVFDLVNREAFNQSFGVNVTGIRENYLQLSIGQGNSVFISLVPSSQGDQAVDSAGNQDLENAILPLDTLDGVKLPEENSDSSTKELGIPDRTSCEIYLQQIFHENIFSRAKDKPVLTVARISSQTAKEGSSLLGHFCMSLAHRIFSKKVLRVLENLVSGVPYLQLLSHPTWHSRTSSWTLFMKIPQSILYAGTQTPTSDLHYVKTTTKSQFRTKVVVTDDFITVEGEGAPSVVGLFKGNSQESSSMKRYECNLQDLPVIILQQVAGQIIRWLHEEALMVGIKVNRDFLSLSFELEQGETLSLTAHVDPEDSQGCISWWLIMEDGFAEEGKLHLDLSDGVSEYRKFLGHLSLDVLYSTLMDLILQSPINNTRAESSTKLLKYPSQVSYNRALLLPYEDFWLGVVDWSREKPSESYHLGIAEDYKSECGSQEFQVFILDSLSKGRGELDCANGFCS |
Length | 744 |
Position | Head |
Organism | Trema orientale (Charcoal tree) (Celtis orientalis) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
rosids> fabids> Rosales> Cannabaceae> Trema.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.330 |
Instability index | 48.57 |
Isoelectric point | 5.31 |
Molecular weight | 83618.57 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP19369
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 181.69| 60| 68| 387| 451| 1
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387- 451 (87.53/67.01) YLQQIFHENIFSRAKD.....KPVLTVARISSQTAKegSSLlgHFCMSLAHRIFSKKVLrVLENLVS....GVP
452- 520 (94.17/55.88) YLQLLSHPTWHSRTSSwtlfmKIPQSILYAGTQTPT..SDL..HYVKTTTKSQFRTKVV.VTDDFITvegeGAP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 171.72| 52| 400| 168| 344| 2
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288- 344 (76.28/199.72) FDEQVFDLvNREAFNQSFGVnvtGIRENYLQLSIGQGNSVFIsLVPSSQGDQAVDSA
688- 739 (95.44/20.38) FWLGVVDW.SREKPSESYHL...GIAEDYKSECGSQEFQVFI.LDSLSKGRGELDCA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 92.40| 29| 269| 257| 287| 5
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257- 287 (45.99/29.53) NSRESekDAGSDDECIIKEMH.LLLRQVHQTI
529- 558 (46.41/24.56) NSQES..SSMKRYECNLQDLPvIILQQVAGQI
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