<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19367

Description "Mediator complex, subunit Med25, von Willebrand factor type A"
SequenceMAEKQLIVAVEGTAAMGPYWHSIVSDYLEKIIRYFCGSEFTGQKTSSSTFELALVIFNTHGSYCGCLVQRSGWTRDIDNFLQWLSAIPFSGGGFSDAAIAEGLSEALMMFPSAQNGNQSQQNVDCQRHCILIAASNPHPLSTPVFRPQIQSLDQSENTDSQTENRLSDAETIAKSFSQCLVSLSVISPKQLPKLRAIYNAGKRNPRANDPPVDNAKNPHFLVLISENFLEARAALSRAGVPSLPSNQSPVKMDMASNTSVTGPPPTSMPSVNGSVMNRQPISVGNMPPATVKVEPTTVSSMVSGPTFSHLPSVARATSQGVPLQTSSPSSASQDMITNNDAGPDLKPPVSSVSQPLRPVGPPPPANVNILNNLSQARQVMHSAALPMGQTPIGMHMSNMISSGMASSTPAQNIVPSGQSVITSMAASGTLTQVPQNPGLTQVTQNPGLTQVAQNPGLAQFTAANNNVSGNSNIGVSQPLSNLQGGVSMGQSVPAMSQGNLSGSQMVQSGMGMNQNMINGLGSSVVSSGSSTMIPTPGMSQQQVQPGVQTLGVNNSSAANIPLSQQASNPPQPPQPSKYVKVWEGNLSGQRQGQPVFITRLEGYRNATASETLAANWPATMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLGQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDKSVYGSTEFVPIWTKYYAVFSGPLSLGVEASGVITERKRVRPPPTLT
Length739
PositionUnknown
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.05
Grand average of hydropathy-0.208
Instability index51.07
Isoelectric point8.91
Molecular weight78337.95
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19367
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     243.41|      28|      42|     364|     391|       1
---------------------------------------------------------------------------
  238-  265 (26.09/ 6.84)	.AGVPSLpSNQSPVKMDMASNTS.......VTGPPP
  304-  327 (25.57/ 6.55)	GPTFSHL.PSVARAT....SQGV.......PLQTSS
  364-  391 (48.05/18.75)	PANVNIL.NNLSQARQVMHSAAL.......PMGQTP
  409-  434 (28.02/ 7.88)	PAQ.NIV.PS.GQSVITSMAASG.......TLTQVP
  462-  492 (26.21/ 6.90)	AAN.....NNVSGNSNIGVSQPLsnlqggvSMGQSV
  493-  514 (29.16/ 8.50)	PAMSQ...GNLSGSQ..MVQSGM.......GMNQ..
  536-  556 (30.44/ 9.20)	PGMSQ.......QQVQPGV.QTL.......GVNNSS
  557-  574 (29.86/ 8.88)	AAN..I..P.LSQQ....ASN.........PPQPPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.43|       9|     115|     398|     407|       2
---------------------------------------------------------------------------
  398-  407 (13.76/ 9.74)	NMIsSGMASS
  515-  523 (17.68/ 7.75)	NMI.NGLGSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.84|      11|     129|     577|     587|       3
---------------------------------------------------------------------------
  577-  587 (21.65/13.12)	KYVKVWEGNLS
  707-  717 (20.20/11.76)	KYYAVFSGPLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     169.95|      54|     431|     170|     231|       8
---------------------------------------------------------------------------
  170-  231 (79.64/78.56)	ETIAKSFSQCLVSLSVISPKQLPKLRAIynaGKrnpraNDPPVDNAKNPH.FLVLISENFLEA
  610-  664 (90.31/65.22)	ETLAANWPATMQIVRLISQDHMNNKQYV...GK.....ADFLVFRAMNQHgFLGQLQEKKLCA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.94|      15|      33|     111|     126|       9
---------------------------------------------------------------------------
  111-  126 (24.75/18.23)	PSAQNGNQSqQNVDCQ
  147-  161 (27.19/15.06)	PQIQSLDQS.ENTDSQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19367 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LSRAGVPSLPSNQSPVKMDMASNTSVTGPPPTSMPSVNGSVMNRQPISVGNMPPATVKVEPTTVSSMVSGPTFSHLPSVARATSQGVPLQTSSPSSASQDMITNNDAGPDLKPPVSSVSQPLRPVGPPPPANVNILNNLSQARQVMHSAALPMGQTPIGMHMSNMISSGMASSTPAQNIVPSGQSVI
2) SMAASGTLTQVPQNPGLTQVTQNPGLTQVAQNPGLAQFTAANNNVSGNSNIGVSQPLSNLQGGVSMGQSVPAMSQGNLSGSQMVQSGMGMN
3) SVVSSGSSTMIPTPGMSQQQVQPGVQTLGVNNSSAANIPLSQQASNPPQPPQPSKYVKVWEG
235
423
523
421
513
584










Molecular Recognition Features






MoRF SequenceStartStop




1) KLRAIY
193
198