<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19363

Description Tyrosine-protein kinase
SequenceMKLLKPSHPPSHGPSPESLSGFSSPASFRLGFDRGASSQLPEIVEDDGNKVVHVAVGKSVEKAMSLLNWTFRRFEGKGVCILHVYQPSQLIPTHCESLLLGKLPASQANAEVVSTYRKYEREETTKLLQIYLSICSGAKVSASIITIEADQVQKGIVNLVNKHGIRKLVMGAVPENCMKVKKSSSKAYYAATNAPLFCEIWFINKGKHLWTRDSSEDPSSLPSRSQPQLATVGNSIFRSFQYGKNKSIQANWLRSNSARSAISAEISNRIQCEPVHVDLASSSTLSCSTSPCLHDLNGSFSPASTGSGYYSGERRVSSDSDEEKLYSQLIDARIEAEASRNEAFTDLLKLRKLESEAREAISKVKGFESALAREVKLREEAEDALKTTLEEQEKLLEEREDISLELRRTMRNVALLDSRAQEANRRHDEAAGELKLVQESIATLRQEKQRIRKQKMEALHWLERWRNRGQGGAANCTGLIGFIDELPELAEFSLSDLQTATCNFSESFKIGKGGFGCVYKGEMLGRTVAIKKLHPYNMQGESEFQQEVKVLGKLQHPHLVTLLGVCPEAWSLVYEYLPNGSLQDHLFRKNNVLTWEIRARIIAEIASALCFLHSSKPEKIVHGDLTPRNILLDSALSCKICDFGICRLINEDNLHCPSLRWTNGPKGAFSYTDPEFQRIGILTPKSDAYSFGLIILQSLTRRSPVGLTGEVRKAVSSGKLASILDSSAGEWPTLVVRRLVDLGLQCCELNGRDRPEITPSLVRELEQLHGSEERPVPSFFLCPIFQEIMHDPQVAADGFTYEGEAMRGWLENGKETSPMTNLKLGHLHLTPNHAIRLAIQDWLCKA
Length846
PositionTail
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.07
Grand average of hydropathy-0.345
Instability index47.46
Isoelectric point7.53
Molecular weight94201.32
Publications









Function






Annotated function

Functions as an E3 ubiquitin ligase.



GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19363
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.66|      34|     207|     228|     313|       1
---------------------------------------------------------------------------
  278-  313 (57.76/92.09)	DLASSSTLSCSTSPClhDLNGSFSPASTGSGY.YSGE
  488-  522 (57.89/14.13)	ELAEFSLSDLQTATC..NFSESFKIGKGGFGCvYKGE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.63|      26|     209|       6|      31|       2
---------------------------------------------------------------------------
    6-   31 (50.18/30.08)	PSHPPSHGPSPESLSGFSSPASFRLG
  218-  243 (47.46/28.04)	PSSLPSRSQPQLATVGNSIFRSFQYG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.53|      14|      16|     328|     343|       4
---------------------------------------------------------------------------
  328-  343 (18.33/15.16)	QLIDAR.IEAEAsrNEA
  346-  360 (18.20/ 8.28)	DLLKLRkLESEA..REA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.80|      13|      15|     371|     383|       5
---------------------------------------------------------------------------
  371-  383 (21.17/13.60)	LAREVKLREEAED
  389-  401 (21.63/14.06)	LEEQEKLLEERED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.66|      20|     193|     457|     477|       7
---------------------------------------------------------------------------
  457-  477 (36.87/27.37)	EALHWLE.RWRNrGQGGAANCT
  652-  672 (37.80/23.05)	DNLHCPSlRWTN.GPKGAFSYT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19363 with Med32 domain of Kingdom Viridiplantae
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