<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19361

Description Mitogen-activated protein kinase kinase kinase
SequenceMNDDGDSGVPAPMTSVAVAVHGGSGGSGGNGSRRAVKWAVENLMDRADRFVLVHVMPKISSIPTPSGDWIPVAEIDADMVTMYVEEIKEKVQEIFIPFKKLCKSRTMETLILEGDDPAWALLKYMSESGISCLVMGSCSSNFLTRKLKGPGVPTSVLSYTANPCDIYVVSKKRIVTKAANSSHSGDTSSAHRVSTQRDNREGFRGFDEQVSGLDSFSAESRERNHQNLENGIGTLSLRECNSVASLDADKLDSQAEVEQLRQELQNTIAMYKRACEELVHAQKKVQLVSSVCLEETRRVNVALEREESSKRIAAEEKAKHLEAIKEVERARVLLAKEAYERQIAEVNALEESSEKRKLVEALFSSDKRYRRYTWNEIEIATDFFSETNVIGEGGYGKVYKCSLDHTPVAVKVLQNGADEKKHEFLKEVEVLSQLHHPNIVLLLGACPERGCLVYQYMENGSLEDYIYRWNGKSQLPWFIRFRIAFEIACGLAFLHNAKPEPIVHRDLKPGNILLDSNYVSKIGDIGLAKIISEVVPDSITEYRDSMLAGTLFYMDPEYQRTGTIRPKSDLYAFGIIILQLLTSRHPNGLLLTVENAMRNGSFIDILDKSVTDWPLVETEELARIALKCSNLRCRDRPDLDAEVLPALKRLVDIANTSAEVERHNIHAPSHYYCPILQEIMDDPYIAADGFTYEHRAIKAWLEKHNVSPSTKQKFQHSMLTPDHTLRSAINDWRSRVTFAGI
Length741
PositionTail
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.07
Grand average of hydropathy-0.340
Instability index45.08
Isoelectric point5.91
Molecular weight83199.68
Publications









Function






Annotated function

Functions as an E3 ubiquitin ligase.



GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19361
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.05|      32|     170|      72|     103|       2
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   72-  103 (54.22/41.62)	VAEIDADMV..TMYVEEIKEKVQEIFIPFKKLCK
  243-  276 (47.83/35.83)	VASLDADKLdsQAEVEQLRQELQNTIAMYKRACE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19361 with Med32 domain of Kingdom Viridiplantae
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