Description | "Mediator complex, subunit Med" |
Sequence | MDIISQLQEQVNTIAALAFNTFGTLQRDAPPVRLNAEYPDPPPAPAPDDPTKFSEQPKLMSSALVKAAKQFDALVAALPLADGGEEAQLKRIAELQAENDAVGQELQRQLEAAENELKQVQELFSQAADNCLNLKKPD |
Length | 138 |
Position | Middle |
Organism | Trema orientale (Charcoal tree) (Celtis orientalis) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.441 |
Instability index | 54.05 |
Isoelectric point | 4.40 |
Molecular weight | 14993.68 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP19360 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 32.71| 10| 27| 86| 95| 2 --------------------------------------------------------------------------- 86- 95 (16.02/11.63) EAQLKRIAEL 114- 123 (16.69/12.40) ENELKQVQEL --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EAQLKRIAELQAEND 2) PDDPTKFSEQPKLMSSALVKAAKQFDALVAALPL 3) VRLNAEYPDPP | 86 47 32 | 100 80 42 |
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