<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19353

Description Mediator of RNA polymerase II transcription subunit
SequenceMAVYVQTSLCDSVMELTKVAQQKGSDPLLWAIQLSSNLSSAGVSLPSVEVANSLVSYICWENNVPIMWKFLEKALVLKIVPPMLVLALLSTRVIPSRGSQPVAYRLYMELVKRHVFNLKSQINGPNCEMVMKSIDDVLRLSTKFGLLASEPGIVAVEFIFSMAWQLLDASLDDEGLLNRTLEQNSIWATIPQEMEIDGHCSYEEKWTEHNEILKNANTVMAIEIIGELLRNKVTSRILFLARRHLPTHWTSFIRRFRVLGENSSALRNSKTVSPEALLQLLADTCIVLSRECKTSSLHKFHAVMAFGSLASSAGLCHGASRSALWLPLDLVLEDAMDGYQVDATSAVERITGLIKTLQAINGTTWHDTFLGLWIAALRLIQRERDPIEGPVPHLDSRLSILLCITTLVVADLIEEEEGAPLEETECGSTNQWKEKKEASGKRRNDLVSSLQMLGDYQGLLAPPQSVVPVANQAVAKAMFIPSGVGVGNAYFECLSVKDMPINCSGNMRHLIVEACIARNLLDTSAYFWPGYINGCVNQMPQGVPTQVPGWSSFMKGATLSPLMINSLVSSPASSLAELEKIFEIAINGSNDERISAATILCGASLIRGWNIQEHTAYFIIRLLSPPVPADYAGVDSHLIGYAPMLNVLIVGIASVDCVQIFSLLGLVPQLACSLMPICEVFGSCVPNISWTLTSGEEISAHAVFSNAFILLLKLWRFNHPPLEHGVGDVPTVGSQLTPEYLLAVRNSYLKSSGNAFKDQNKRRLSAVASSSSPQAVFVDSFPKLKAWYRQHQACIASTLSGLVHGTPVHQIVDGLLNMMFRKIGRGSQSLTSATSGSSSSSGPGIEDSSVRPKLPAWDILEAVPFVVDAALTACAHGTLSPRELATGLKGLADFLPASLAGIVSYFSAEVTRGIWKPAFMNGTDWPSPAANLSNVEEQIKKILAATGVDVPSLAAGGSSPATLPLPLAAFVSLTITYKIDKASERFLNLAGPALESLAAGCPWPCMPIVASLWTQKAKRWTDFLVFSASRTVFLHNSDAVVQLLKSCFTAALGLNAIPISSNGGVGTLLGHGFGSHFCGGMSPVAPGILYLRVFRSMRDIVFTTEEIVAILMHSVREIACSGLPREKLEKLKTAKKNGVSYGQVSLAAAMTRVKLAASLGASLVWLTGGLFLVQSLIKETLPSWFISKHRSEHEEGSSEGMVAMLGGYALAYFVVLCGAFAWGVDSSSAASKRRPKVLGTHMEFLASALDGKISLGCDGATWRAYVLSFLSLMVGCTPNWVLEMDVDVLKRLSNGLKQWNEVELALALLGVGTMGAAAELIVENEM
Length1326
PositionTail
OrganismParasponia andersonii (Sponia andersonii)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Parasponia.
Aromaticity0.07
Grand average of hydropathy0.241
Instability index43.18
Isoelectric point6.34
Molecular weight143333.51
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19353
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     225.78|      58|     637|     313|     373|       1
---------------------------------------------------------------------------
  313-  373 (93.57/69.94)	AGlcHG.ASRSALW..LP.LDLVLEDAMDGYQVDATSAvERITGLI.KTLQAI.NGTTW..HDTFLGLW
  876-  925 (50.05/27.18)	....HGtLSPRELAtgLKgLADFLPASLAGI.VSYFSA.EVTRGIWkPAF..M.NGTDW..........
  955- 1013 (82.15/50.73)	AG...G.SSPATLP..LP.LAAFVSLTIT.YKIDKAS..ERFLNLAgPALESLaAGCPWpcMPIVASLW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.52|      43|     247|     759|     845|       5
---------------------------------------------------------------------------
  699-  755 (60.99/23.67)	SAHAVFSNAFIlLLKLW.RFNHPP.......LEHGvgdvptvgsqlTP.....EYLLAV......RNSylKSSGNA
  772-  833 (59.53/114.05)	SPQAVFVDSFP.KLKAWyRQHQACiastlsgLVHG...........TPvhqivDGLLNMmfrkigRGS..QSLTSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.05|      20|     932|     238|     264|       7
---------------------------------------------------------------------------
  242-  264 (29.16/35.86)	RRHLPThWtsFIRRFRVLGENSS
 1178- 1197 (37.89/19.79)	KETLPS.W..FISKHRSEHEEGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.69|      22|     126|     489|     511|       9
---------------------------------------------------------------------------
  489-  511 (39.44/24.34)	AYF..ECLSvKDMPINCSGNMRHLI
  616-  639 (34.25/16.88)	AYFiiRLLS.PPVPADYAGVDSHLI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19353 with Med33 domain of Kingdom Viridiplantae
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