<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19352

Description GPCR kinase
SequenceMGDGGNRGLVGSGNSNNNGGNGSSGNKPEWLQQYDLIGKIGEGTYGLVFLARTKSPGNRGKSIAIKKFKQSKDGDGVSPTAIREIMLLREITHDNVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHRDKVNHAIHQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGEEQGVVKIADFGLARIYQAPLKPLAENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGAEVKATPNPFQLDQLDKIFKVLGHPTLEKWPTLANLPHWQQDTQHIQGHNDNNHGLHGFVHLPLKSPAFDLLSKMLEYDPRKRITAAQALEHEYFRLEPLPGRNALVPSQGEKVVNYPTRPVDTTTDFEGTTSLQPSQPVSSGNAVSGNMAGAHGVPGRSVPRPMLGMQRMQPQGMTGYNLASQAGMGGGMNPGGIPMQRGVNPQAHQQQQLRRKDPGMGMSGYPPQQKQRRM
Length482
PositionKinase
OrganismTrema orientale (Charcoal tree) (Celtis orientalis)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Trema.
Aromaticity0.07
Grand average of hydropathy-0.475
Instability index34.85
Isoelectric point9.26
Molecular weight53278.14
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19352
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.33|      23|      36|       1|      24|       1
---------------------------------------------------------------------------
    1-   24 (38.20/24.55)	MGDgGNRGLVGSGNSNNNGGNGSS
   40-   62 (41.12/21.97)	IGE.GTYGLVFLARTKSPGNRGKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     273.99|      52|      53|     309|     360|       2
---------------------------------------------------------------------------
  258-  304 (66.53/32.46)	....PFQLDQLDKIFKV.....LGHP..TLEKWPTLANLPHWQQ.DTQHIQGHND..NNHG
  309-  360 (80.11/40.49)	VHL.PLKSPAFDLLSKM.....LEYD..PRKRITAAQALEHEYF.RLEPLPGRNALVPSQG
  364-  416 (69.06/33.96)	VNY.PTR.PV.DTTTDF..egtTSLQ..PSQPVSSGNAVSGNMA.GAHGVPGRSVPRPMLG
  418-  477 (58.29/27.59)	QRMqPQGMTGYNLASQAgmgggMNPGgiPMQRGVNPQAHQQQQLrRKDPGMGMSGYPPQQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.50|      30|      44|     168|     201|       4
---------------------------------------------------------------------------
  168-  201 (43.00/48.25)	PSniLVMGEGEEQGVVKIADFGLarIYQA..PLKPL
  215-  246 (49.50/38.77)	PE..LLLGAKHYTSAVDMWAVGC..IFAEllTLKPL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19352 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALVPSQGEKVVNYPTRPVDTTTDFEGTTSLQPSQPVSSGNAVSGNMAGAHGVPGRSVPRPMLGMQRMQPQGMTGYNLASQAGMGGGMNPGGIPMQRGVNPQAHQQQQLRRKDPGMGMSGYPPQQKQRRM
354
482










Molecular Recognition Features






MoRF SequenceStartStop




1) QLRRKDPGMGMSGYPPQQKQRRM
2) RGKSIAIKKFK
460
59
482
69