<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19332

Description Mediator of RNA polymerase II transcription subunit
SequenceMAVSVQKTATSHLWDTVLEITKSAQDRNSDPLLWAIQLSSNLNSAGVSLPSVDLAHLLISHICWANHVPITWKFLEKALTVKIAPPMLVLALLSTRVIPNRQLHPTAFRLYMELLKRHSFSFTSQTNVLNQKVMKSIDEVLHLSELFGLEVSEPGLLLVEFVFSIVWQLLDASLDDEGLLELTPEKKSRWPTRPQDMEIDGQDCFSEKRSDNEVLHKANTAMAIEIIVEFLKNKVTSRLLCLARRNMPSHWGCLIQQLQLLAANSSVLRSLKHITPEVFMQLTSDTRRLLTRECKTISQHDFHAVLASGSTLSPARQSHGASSSSIWLPFDLFLEDAMDGSQVAATSAVDTLIGLVKALQAVNSTAWHNTFLGLWISALRLVQRERDPREGPVPRLDTCLCMLLSISTLAITNIIEEEESKLMEETEQSSTNQRIDKQALGQRRKDLVISLQLLGDFEGLLTPPQCVSSAANQAAAKAMMFISGLTVSNGYYESSTLNDMPINCIGNMRHLIVEACIARNLLDTTAYFWPGYVNACSNQLSRNIPSQVTGWSSLMKGSPLTPALVNALIATPASSLAEIEKIYEIAINGSDDEKISAANILCGASLVRGWSIQENACLFIIGLLSPRVPVDYSGSESHLICYAPLFNVLLVGISSIDCVQIFSLHGLVPLLAGALMPICEVFGSSVPNSWTLPTGEELSCHAIFSNAFTLLLRSWRFDHPPLEHMMGDVRPTVGSELSPEYLLLVRNSRLASVGTSAKDRIKSRRVSKFITFSTDPILMDSFPKLKLWYQQHQKCICSTLSGLVPGTPVHQIVDALLNMMFRKISRGNQPLTPTTSGSSTSSVSGTDESSIRLKVPAWDILEATPFVLDAALTACAHGRVSPRELATGLKDLADYLPATLATIVSYFSAEVTRGIWKPAHMNGTDWPSPAANLSIVEQQIKKILAATGVDVPSLSVGGSSPATIPLPLAALISLTITFKLDKASERALQLIGPALNSLATGCPWPCMPIIASLWAQKVKRWGDFLVFSASQAVFHHNSDAVVQLLKSCFTSTLGLSSSHIHSNGGVGSLLGHGFGSFSGGISPVAPGFLYLRVHRSVRDVVFLTEEILSLLMLSVKEIASCGLPKEKLEKLKRSKYGLRYGHVSMATAMARIKLAASLGASLVWLTGRSSLVQCLIKETLPSWFISAHGSEQEGQESGGTVSVLGGYALAYFAVLSGTFAWGVDPATPTSNRRSKILGAHLDFLASALDGKISLGCDSATWRAYVSGLMSLLVGCAQNWMMEIDVDILKRLSKGLRQWDEEELALAVLGLGGVGAMGAAAELVIESDF
Length1328
PositionTail
OrganismParasponia andersonii (Sponia andersonii)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Parasponia.
Aromaticity0.07
Grand average of hydropathy0.170
Instability index45.86
Isoelectric point6.50
Molecular weight144422.29
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19332
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     150.66|      33|     175|     610|     654|       1
---------------------------------------------------------------------------
  610-  643 (58.85/31.76)	WSIQENACLFII.........GLLSPRVPvDYSGSESHLICYA
  788-  815 (51.04/22.20)	WYQQHQKC..IC.........STLSGLVP....GTPVHQIVDA
  858-  896 (40.77/18.63)	WDILE.ATPFVLdaaltacahGRVSPR...ELATGLKDLADYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.79|      51|     272|     943|    1023|       2
---------------------------------------------------------------------------
  968- 1022 (75.93/90.48)	LAALISLTITFKLDKASERAlQLIGpaLNSLATGCP..WpCMPI...IASLWAQKVKRWG
 1244- 1299 (81.85/40.64)	LASALDGKISLGCDSATWRA.YVSG..LMSLLVGCAqnW.MMEIdvdILKRLSKGLRQWD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     178.60|      60|     338|       6|      66|       3
---------------------------------------------------------------------------
    6-   66 (100.31/72.53)	QKTATSHLwDTVLEITKSAQDRNSDPL......LW..AIQLSS.NLNSAGVSLPSVD..LAHLL.ISHICWAN
  342-  413 (78.29/49.96)	QVAATSAV.DTLIGLVKALQAVNSTAWhntflgLWisALRLVQrERDPREGPVPRLDtcLCMLLsISTLAITN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     276.90|      76|     246|     246|     341|       5
---------------------------------------------------------------------------
  246-  324 (120.39/79.97)	NMPSHwgClIQQLQLLAANSSVLRSLKHITPEVFMQLTSDTRRLLT.REC..KTISQHDFHAVL.ASGSTLSPA.RQSHGASSS
  451-  496 (35.48/10.99)	..................................LQLLGDFEGLLTpPQCvsSAANQAAAKAMMfISGLTVS....NGYYESST
  499-  573 (121.03/68.76)	DMPIN..C.IGNMRHLIVEACIARNLLDTTAYFWPGYVNACSNQLS.RNI..P..SQVTGWSSL.MKGSPLTPAlVNALIATPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.37|      23|     272|     670|     693|       6
---------------------------------------------------------------------------
  670-  693 (41.13/25.33)	LLA..GALMPICEVFGSSvPNSWTLP
  943-  967 (37.24/18.56)	ILAatGVDVPSLSVGGSS.PATIPLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.02|      18|     246|     816|     833|       7
---------------------------------------------------------------------------
  816-  833 (34.00/21.32)	LLNMMFRKISRGNQPLTP
 1069- 1086 (34.02/21.33)	LLGHGFGSFSGGISPVAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19332 with Med33 domain of Kingdom Viridiplantae
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