<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19326

Description "Mediator complex, subunit Med25, von Willebrand factor type A"
SequenceMGVKFLAVVVDGTAATEPHWSNIVIHYLEKIIRCISDGSEDSGSEVELSLITYRRDGLHNKDPLPSPWTRSADSFVQRLWSVEFIGCSPSEANIAQALAEALHMLPKPYDKTHEEYRQHWFSAEKHCILVIASNPFVDKYYGRFTSLKSVAKNFAEYSVTLSVISPKRFPNLRGIFNWANNITPEEAAFVNEKVNIYNLHGYLVLLSEKFPEAHSAISEEQMSILIMNACTSSPTCSSTDQDQDQETVTDNHSIPPNSETNNISEEDVRLLKQMLDEDFSTDMDEDQNQENFVIMPGLYPLSYANSSTTTTTSSGLVDFQSQNNKTRYETILEDLLGAEEGVSDNLRDQPKTVMSSNTAGPEYETLPLTLESEAPMVTEEVAENNNVSFNGATGNFDILQPADQLQMIQSINETSSQIMTTDSVVITSMSTASYSYTSQPAGGFQPTSTYDGQFRNSSQSDTLTGGARPGGFLLGNPRLVQTTRASWFASSPNSASSVNLRIPGAFSGGQEPSRLAGNWQPRLNPGVVENGSSSTRDVVGAFNHVFGESSEVRPLVPVMERPLRIHGGMGPIGPSNQKYEQDGYVLTWEGNFVAKYSRGIIHTGRVKAYKKSSAPQTLTADWPRTMKIAHVLYQHAFNRLPYQGQADIVVFEAQAEHSVYEHLKKSELCVIMDLPSQTLIFSPTERKLRFIGTLFRGHLPLFRSETYFGQLAVPRRPQQPRHEQNDHEAESKERIIDCLVRDEGDENLGGSCNTGSTKPSS
Length761
PositionUnknown
OrganismParasponia andersonii (Sponia andersonii)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Parasponia.
Aromaticity0.08
Grand average of hydropathy-0.475
Instability index48.97
Isoelectric point5.10
Molecular weight84453.99
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19326
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.93|      20|      38|      64|      83|       1
---------------------------------------------------------------------------
   64-   83 (37.59/25.63)	LPSPWTRSADSFVQRLWSVE
  105-  124 (39.33/27.17)	LPKPYDKTHEEYRQHWFSAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.91|      40|      43|     217|     258|       2
---------------------------------------------------------------------------
  217-  258 (66.26/40.10)	ISEEQMSILimNACTSSPTCSSTDQDQDQETVTDNHSIPPNS
  263-  302 (66.65/34.98)	ISEEDVRLL..KQMLDEDFSTDMDEDQNQENFVIMPGLYPLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.18|      16|      42|     463|     479|       3
---------------------------------------------------------------------------
  463-  479 (27.19/20.35)	LTGGARPgGFLLGN..PRL
  506-  523 (26.99/14.77)	FSGGQEP.SRLAGNwqPRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.12|      15|      43|     153|     171|       4
---------------------------------------------------------------------------
  153-  171 (22.35/30.78)	NFAEYSVTLSvispKRFPN
  198-  212 (27.77/22.23)	NLHGYLVLLS....EKFPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      64.27|      13|      32|     355|     367|       6
---------------------------------------------------------------------------
  355-  367 (23.61/14.96)	SSNTAGPEYETL.P
  388-  401 (18.21/ 9.65)	SFNGATGNFDILqP
  428-  440 (22.44/13.81)	SMSTASYSYTSQ.P
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19326 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TCSSTDQDQDQETVTDNHSIPPNSETNNISEEDVRLLKQMLDEDFSTDMDEDQNQENF
2) YETILEDLLGAEEGVSDNLRDQPKTVMSSNTAGPEYETLPLTLESEAPMVTEEVAENNNVSFN
3) YTSQPAGGFQPTSTYDGQFRNSSQSDTLTGGARPGGFLLG
235
328
436
292
390
475










Molecular Recognition Features






MoRF SequenceStartStop




1) SKERIIDCLVRDEGD
731
745