<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19324

Description "Mediator complex, subunit Med25, von Willebrand factor type A"
SequenceMAEKQLIVAVEGTAAMGPYWHSIVSDYLEKIIRYFCGTEFSGQKTSSSTFELALVIFNTHGSYCGCLVQRSGWTRDIDNFLQWLSAIPFSGGGFSDAAIAEGLSEALMMFTSAQNGNQSQQNVDCQRHCILIAASNPHPLSTPVFRPQIHSLDQSENADSQTENRLSDAETIAKSFSQCSVSLSVISPKQLPKLRAVYNAGKRNSRANDPPVDNAKNPHLLVLISENFLEARAALSRAGVPSLPSNQSPVKMDMASNTSVTGPPPTSMPSVNGSVMNRQPISVGNMPPATVKVEPTTVSSMVSGPTFSHLPSVARATSQGVPLQTSSPSSASQDMITNNDAGSDLKPPVSSVSQPLRPVGPPPPANVNILNNLSQARQVMHSAALPMGQTPIGMHMSNMISSGMASSTPAQNIVPSGQSVITSMAASGTLTQVPQNPGLTQVAQNPGLTQFTATTNNVSGNSNIGVSQPLSNLQGGVSMGQSVPAMSQGNLSGSQMVQSGMGMNQNMMNGLGSSVVSSGSSTMIPTPGMSQQQVQPGVQTLGVNNSSAANIPLSQQASNPPQPPQPSKYVKVWEGNLSGQRQGQPVFITRLEGYRNATASESLAANWPATMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLGQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDKSVYGSTEFVPILTENYAVLSGPLSLGVEASGVITKRKRVRPPPTLT
Length730
PositionUnknown
OrganismParasponia andersonii (Sponia andersonii)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Parasponia.
Aromaticity0.05
Grand average of hydropathy-0.202
Instability index52.03
Isoelectric point8.92
Molecular weight77182.63
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19324
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     111.14|      21|      39|     250|     270|       1
---------------------------------------------------------------------------
  250-  270 (39.21/18.44)	VKMDMASNT...S.VTGPPPTSMPS
  291-  312 (25.60/ 9.32)	VKVEPTTVS...SmVSGPTFSHLPS
  331-  354 (24.03/ 8.27)	ASQDMITNNdagS.DLKPPVSSVSQ
  356-  369 (22.31/ 7.12)	LR..........P.VGPPPPANVNI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     365.26|      83|      85|     414|     498|       2
---------------------------------------------------------------------------
   84-  165 (47.86/15.99)	..................LSAI.PfSGGGFSDAAIAEGLSEalmmFT.......SAQNGNQSQQnvdcqrhciliaASNPhPlSTPvfrpqihSLDQS......ENADSQTENR
  166-  218 (52.97/18.28)	LSD.AETIAKSFSqCSVSLSVIsPkQLPKLRAV.YN...........AGKRN.SRANDPPV.DN............AKNP..................................
  414-  498 (132.35/62.79)	VPS.GQSVITSMA.ASGTLTQV.P.QNPGLTQVAQNPGLTQ....FTATTNNvSGNSNIGVSQP............LSNL.Q.GGV.......SMGQSVPaMSQGNLSGSQMVQ
  508-  584 (132.07/56.92)	MNGlGSSVV.....SSGSSTMI.P..TPGMSQQQVQPGVQ......TLGVNN.SSAANIPLSQQ............ASNP.P.QPP.......QPSKYVK.VWEGNLSGQRQGQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19324 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LSRAGVPSLPSNQSPVKMDMASNTSVTGPPPTSMPSVNGSVMNRQPISVGNMPPATVKVEPTTVSSMVSGPTFSHLPSVARATSQGVPLQTSSPSSASQDMITNNDAGSDLKPPVSSVSQPLRPVGPPPPANVNILNNLSQARQVMHSAALPMGQTPIGMHMSNMISSGMASSTPAQNIVPSGQSVI
2) SMAASGTLTQVPQNPGLTQVAQNPGLTQFTATTNNVSGNSNIGVSQPLSNLQGGVSMGQSVPAMSQGNLSGSQMVQSGMGMNQNMMNGLGSSVVSSGSSTMIPTPGMSQQQVQPGVQTLGVNNSSAANIPLSQQASNPPQPPQPSKYVKVWEG
235
423
421
575










Molecular Recognition Features






MoRF SequenceStartStop




1) YVKVWE
569
574