<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19313

Description "Coactivator CBP, KIX domain containing protein"
SequenceMDNNNWRPVQGGEPTMDTTDWRTQLQPDSRQRIVNKIMDTLKKHLPFSGQEGLQELKKIAERFEEKIYAAATSQSDYLRKISLKMLTMETKSQNTISNALPSNPGGNNSRPPDSGSLVIQPQGHNQGQSLAMPLPPNQSQTRQQLLSQNIQNAAAVQSSSSLSSVLPPPSSLGQTSIPSGVGQNANMQNIPGNSQNSAGNSMGQGVPANMYANTQRQMQGRQQVVPQQQQQSQNPQQSYLYQQQQLQQQILKPKFQQGNISQSMMQSHIQQQQQQQSLLQPTQLQSSQQASSTMQPSLMQSSLPSLQQNQPSSIQQQTKPMLQQHPQSVLRQQQQPQQAAVALQQQAQMSQQQQQLMSQQPNSTNMQQSHLIAQQNNVGDLQQQQRLLGQQNNLPNLQQQQLLAQQNNLSNLHQQQLAPQSNVAGLQQQQQLLGTQTGNSGMQTNQHAVHMLQQSKAPLQQQPQQSGSNLLPTQAQQSQPQQQILSQIQSQPTQMQQQLGLQQQPNALQRDMPQRLQASGQTSGSLLQTHNVIDQQKQLYQSQRALPETSSTSVDSTAQTGHASGGDWQEEVYQKIKTMKESYLPELVEMYQKIAGKLQQLDSLPQQPMSEQLDRLKLFKITLERAIQFLQVPKGSIFPGHKEKLPQYEKQILSFINTNRPRKPVSQLQQGQHPPSSHMHPMQQPQSQINQVQSHENQMNPQLQPINVQGSVGTMQQNNMTSLQQNSMPALSGVSTTQQNVMNSLQPTSDVDSGQGNALNPLQQVTVGSLQQNPVSAPQQANMNALSSQNGINVLQPNINTLQSNSNMLQHQHVKQQQEQQLKQQYQQRQMQQQLMQKQQILQQQQQQQQQQQQQQQQQQQQLQQQAKQQLPAQMQAHQNQMPQLHQINDVNDLKMRQSMGVKPGVFQQHLPAGQRSAYPHQQLKASSSFTISSNQLLQASSPQILQHSSPQVDQQNLLSTLTKAGTPLQSANSPFVVPSPSTPLAPSPIPGDSEKPAPGVSSLSNAGNVGQQQTTGVVAPAQSLAIGTPGISASPLLAEFSGPEGTHANTLAAVSGKSSITEQPLDRLIKAVKSMSPKALSASVSDIGSVVSMMDRIAGSAPGNGSRAAVGEDLVAMTKCRLQVRNFMNQDATNGTRKMKRYTSAMPLNVVSSASSINDSFKQFNGSETSDLESTATSGIKRPKIEANHALIEEIREINQHLIDTVVDIIDEDVDPSVAAAAIEGGEGTIVKCSFSAVALSPNLKSQYASARMSPIQPLRLLVPTNYPNCSPILLDKFPVEVSREYEDLSVKAKSRFSISLRSLSQPMSLGAIARTWDVCARAVMTEHAQQSGGGSFSSKYGTWENCLSAA
Length1352
PositionTail
OrganismParasponia andersonii (Sponia andersonii)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Parasponia.
Aromaticity0.03
Grand average of hydropathy-0.761
Instability index74.40
Isoelectric point9.31
Molecular weight148573.45
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19313
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            10|     736.45|      74|      74|     283|     356|       1
---------------------------------------------------------------------------
  151-  253 (66.80/10.94)	QnaaaVQSSS.SL.................SSVLPPpsS..LG..QTSIPSgvgqnanMQnipgnsQNSagnsmgqgvP.......ANMYANTQRQMQGRQQVVPQ...QQQQsqnPQQS..Y.LYQQQQLQQQ.....ILKP
  283-  356 (134.62/31.28)	Q....LQSSQ.QA.................SSTMQP..S..LM..QSSLPS.......LQ......QNQ.........P.......SSIQQQTKPMLQQHPQSVLR...QQQQ...PQQAAVA.LQQQAQMSQQ.....QQQL
  370-  432 (70.59/12.07)	H....LIAQQ.NN.................VGDLQQ..QqrLLgqQNNLPN.......LQ.............................QQQL..LAQQNNLSNLH...QQQL...APQSNVAgL.......QQ.....QQQL
  433-  499 (88.40/17.41)	......LGTQ.TG.................NSGMQT..N......QHAVHM.......LQ......QSK.................APLQQQ..P..QQSGSNLLPtqaQQSQ...PQQQILS..QIQSQPTQM.....QQQL
  500-  572 (59.86/ 8.85)	G....LQQ..........................QP..N..AL..QRDMPQ......rLQ.....aSGQ.........T.......SGSLLQTHNVIDQQKQLYQS...QRAL...PETSSTS.VDSTAQTGHAsggdwQEEV
  626-  689 (80.03/14.90)	A....IQFLQ.VP.................KGSIFP..G...H..KEKLPQ.......YE......K.Q.........I.......LSFINTNRP...RKPVSQLQ...QGQH...PPSSHM......HPMQQP.....QSQI
  691-  740 (50.36/ 6.00)	Q....VQSHEnQM.................NPQLQP..I..NV..QGSVGT.......MQ......QNN.........M.......TSLQQNSMPALS....GVST...TQQN..............................
  784-  835 (79.58/14.77)	N....ALSSQ.NG.................INVLQP...........NINT.......L................................QSNSNMLQH.QHV.....KQQQ...EQQ.....LKQQYQQRQM.....QQQL
  836-  871 (54.88/ 7.36)	.................................MQK..Q..QI...............LQ......QQQ.........Q..........QQQ.....QQ...........QQQ...QQQQQQQ.LQQQAK..........QQL
  874-  960 (51.32/ 6.29)	Q....MQAHQ.NQmpqlhqindvndlkmrqSMGVKP..G..VF..QQHLPA.......GQ......RSA........yPhqqlkasSSFTISSNQLLQASSPQIL....QHSS...PQ......VDQQNLLS...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.91|      14|      15|     743|     757|       2
---------------------------------------------------------------------------
  743-  757 (21.44/14.05)	NSLQPTSdVDSGQGN
  760-  773 (25.48/12.16)	NPLQQVT.VGSLQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.83|      12|      15|      97|     108|       3
---------------------------------------------------------------------------
   97-  108 (23.22/ 9.56)	SNALPSNPGGNN
  114-  125 (21.61/ 8.40)	SGSLVIQPQGHN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.17|      16|      16|    1255|    1270|       4
---------------------------------------------------------------------------
 1255- 1270 (29.55/16.86)	SPI..QPLRLLVPTNYPN
 1272- 1289 (23.61/12.07)	SPIllDKFPVEVSREYED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     113.75|      28|      28|    1028|    1055|       5
---------------------------------------------------------------------------
  966-  986 (21.45/ 7.85)	..........GTPLQSAnSP....FV..VPSPSTPLA
  987- 1016 (20.95/ 7.47)	PSPIpgdsekPAPGVSS.......LSnaGNVGQQQTT
 1019- 1051 (41.15/23.06)	VAPA.qslaiGTPGISA.SPLLAEFS..GPEGTHANT
 1052- 1080 (30.21/14.61)	LAAV.....sGKSSITE.QPLDRLIK..AVKSMSPKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.64|      14|      17|     573|     586|       6
---------------------------------------------------------------------------
  573-  586 (26.08/15.34)	YQKI..KTMKESYLPE
  591-  606 (20.56/10.46)	YQKIagKLQQLDSLPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.13|      10|      15|    1215|    1224|       8
---------------------------------------------------------------------------
 1215- 1224 (16.10/12.06)	VDPSVAAAAI
 1232- 1241 (17.03/13.25)	VKCSFSAVAL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19313 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KPKFQQGNISQSMMQSHIQQQQQQQSLLQPTQLQSSQQASSTMQPSLMQSSLPSLQQNQPSSIQQQTKPMLQQHPQSVLRQQQQP
2) KQLYQSQRALPETSSTSVDSTAQTGHASGGDWQEE
3) LLQASSPQILQHSSPQVDQQNLLSTLTKAG
4) LQSANSPFVVPSPSTPLAPSPIPGDSEKPAPGVSSLSNAGNVGQQQTTGVVAPAQ
5) MDNNNWRPVQGGEPTMDTTDWRTQLQPDSRQRIVNKIMDTL
6) METKSQNTISNALPSNPGGNNSRPPDSGSLVIQPQGHNQGQSLAMPLPPNQSQTRQQLLSQNIQNA
7) NRPRKPVSQLQQGQHPPSSHMHPMQQPQSQINQVQSHENQMNPQLQPINVQGSVGTMQQNNMTSLQQNSMPALSGVSTTQQNVMNSLQPTSDVDSGQGNALNPLQQVTVGSLQQNPVSAPQQANMNALSSQNGINVLQPNINTLQSNSNMLQHQHVKQQQEQQLKQQYQQR
8) QKQQILQQQQQQQQQQQQQQQQQQQQLQQQAKQQLPAQMQAHQNQMPQLHQINDVNDLKMRQSMGVKPGVFQQHLPAGQRSAYPHQQLKASSSFTISSN
9) QMQQQLGLQQQPNALQRDMPQRLQASGQTSGSLLQT
10) SQQQQQLMSQQPNSTNMQQSHLIAQQNNVGDLQQQQRLLGQQNNLPNLQQQQLLAQQ
11) VAGLQQQQQLLGTQTGNSGMQTNQHAVHMLQQSKAPLQQQPQQSGSNLLPTQAQQSQPQQQILSQIQS
12) VQSSSSLSSVLPPPSSLGQTSIPSGVGQNANMQNIPGNSQNSAGNSMGQGVPANMYANTQRQMQGRQQVVPQQQQQSQNPQQSY
252
537
937
969
1
88
659
837
494
350
423
156
336
571
966
1023
41
153
829
935
529
406
490
239










Molecular Recognition Features






MoRF SequenceStartStop




NANANA