<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19284

Description "DNA helicase, ATP-dependent"
SequenceMRQDRSSWGEGGVAKVELPKVNWSQHIEAHDNFLHQKKFLSSNFLLSLATQRPPNESQDPMATSLGACQSSQRLPNSLVEKAWHVLSSMQISSRNYVKPGKTIYLKGIGTENFHDVGKTTLRCSSDNDRTSAHAQKHQHYGATNPRVSEPASFTGSYCPSSNVEAAEAVKSVGRQRHIRASTVYSSDNQDLGGSIGNHNVHAGQVEESEKVLVTDMDDDEILESIDVDQIVEQYQSSCTPQPSMSKLPPITPSINKSNFVRLNESCLPPELCSTCSHGFKLGTCPEAAHHLQEMKDMLISISNELIDNFDDLSPVQTEKLRQDRLELNKQIQQLERYIRSNSVDEERQKSHFFASTTPRSFHYETPQATASRIDPWKFDSQVHLGNEPGVYESCNSDSYVDRFGVLPSTVEREPYIPKLIEVNYIEGSINKKWSNRDFPWTKKLEANNKKVFGNHSFRPNQREVINATMSGCDVFVLMPTGGGKSLTYQLPAIICQGLTLVVCPLVSLIQDQIMHLFQANIPAAYLSANMEWTEQQEILRELISDYCKYKLLYVTPEKVAKSDALLRHLESLHSRELLARIVIDEAHCVSQWGHDFRPDYQGLGILKRKFPSTPVLALTATATASVKEDVVQALGLVNCIVFRQSFNRPNLRYSVISKTKKCLDDIHKFIKESHYEECGIIYCLSRMDCEKVAERLQECGHKAAFYHGSMDSSQRAFVQKQWSKDEVHIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQQSSCVLYYSYSDYIRVKHMINQGVIEQSPFPSRSNRVNATNSGRILETNTENLLRMVSYCENDVDCRRLLQLIHFGEKFDPSTCKKTCDNCSNIKSCVEKDVTETAKQLVELMKLTGQQFSSSHILEVYRGSFSQFVRKHKHDTLSLHGAGKHLAKGEASRILRHLVIEDILVEEVKKSDVYGSVSSVLKVNQSKAYDLCSGRRTFVLRFPSSVKVTKQSKAGVTPAKGSLLLEKLSPQIDSPVQPQSKEDLILSDMIFSSLRKLRSEILKEASEAGEGLMAYHIFLNASLQEISRRIPKTKEELLEINGIGKGRISKYGDQVLQTIESTINDYMKTTNSSSSNESTDSGKRRRAADQSPNLEDFEFNSTSRSKKMATKRQNNVAEACNNTEQKYYSQYIDDDLDFEDNDFDNNGSGRKTNQNGSGRVLPSWSTPRNV
Length1210
PositionUnknown
OrganismParasponia andersonii (Sponia andersonii)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Rosales> Cannabaceae> Parasponia.
Aromaticity0.07
Grand average of hydropathy-0.552
Instability index55.56
Isoelectric point7.37
Molecular weight136327.20
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19284
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.12|      12|      16|      91|     102|       2
---------------------------------------------------------------------------
   91-  102 (21.84/15.02)	ISSRNYVKPGKT
  108-  119 (22.28/15.50)	IGTENFHDVGKT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     280.82|      81|     318|       1|      88|       3
---------------------------------------------------------------------------
    1-   88 (122.59/90.89)	MRQDRSSWGEgGVAKVElpKVNWSQHIeahDNFLHQKKFLSSNFLLSLATQRPPN.ESQ..DPM....ATSLG.......ACQSS....QRLPNSLVEKaWHVLSS
  257-  303 (44.77/19.54)	.........................................SNFVRLNESCLPPElCST..CSH....GFKLG.......TCPEAahhlQEMKDMLIS....I.SN
  320-  408 (113.47/64.63)	LRQDRLELNK.QIQQLE..RYIRSNSV...DEERQKSHFFASTTPRSFHYETPQA.TASriDPWkfdsQVHLGnepgvyeSCNS.........DSYVDR.FGVLPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.48|      37|     313|     749|     787|       4
---------------------------------------------------------------------------
  749-  787 (63.87/47.69)	IHHSLPKS......IEGYHQecGRAGRDGQQSSCVLYYSYSDYIR
 1066- 1108 (57.61/35.76)	ISRRIPKTkeelleINGIGK..GRISKYGDQVLQTIESTINDYMK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.79|      35|      72|     570|     605|       5
---------------------------------------------------------------------------
  570-  605 (56.80/44.92)	ESLHSRELLARIVIDEAHCVSQwGHDF..RPDYQGLGI
  644-  680 (56.98/38.43)	QSFNRPNLRYSVISKTKKCLDD.IHKFikESHYEECGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.41|      12|      24|     411|     423|       9
---------------------------------------------------------------------------
  411-  423 (18.22/16.37)	ERE.PYIPKLiEVN
  435-  447 (19.19/11.33)	NRDfPWTKKL.EAN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.33|      14|      17|     127|     140|      10
---------------------------------------------------------------------------
  127-  140 (26.62/20.44)	NDRTSAHAQKHQHY
  144-  157 (25.71/19.43)	NPRVSEPASFTGSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|      10|      24|     902|     911|      11
---------------------------------------------------------------------------
  902-  911 (17.48/11.86)	RGSFSQFVRK
  928-  937 (16.81/11.07)	KGEASRILRH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.37|      12|      17|     987|     998|      14
---------------------------------------------------------------------------
  987-  998 (19.76/12.54)	KVTKQSKAGVTP
 1007- 1018 (21.61/14.46)	KLSPQIDSPVQP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19284 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QYIDDDLDFEDNDFDNNGSGRKTNQNGSGRVLPSWSTPRNV
2) RHIRASTVYSSDNQDLGGSIGNHNVHAGQVEESEKVLVTDMDD
3) TINDYMKTTNSSSSNESTDSGKRRRAADQSPNLEDFEFNSTSRSKKMATKRQNNVAEACNNTE
4) VGKTTLRCSSDNDRTSAHAQKHQHYGATNPRVSEPASFTGS
1170
176
1102
116
1210
218
1164
156










Molecular Recognition Features






MoRF SequenceStartStop




NANANA