<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19236

Description Uncharacterized protein
SequenceMAHNLIKPSRLSHAQPPENQNAQPSSDKSPSSLDVYQLQPPRWRLPTQLNRPDLGYPGLHPTHIGQHEDAITKSLVQWGFSAQMLVSTESFSAHQMIYKKITEETAFNVSSSALSALIEARRRYCAMNSHDTKSTIKVPGRVTLNEQKRENWLRELADDSVPLLKLSKNVPHGFKGEKLLEMLVSRKIECSRATWYIRLIGLNEINAQRNKNDLSHIRYTLSFTPEVCQFLQKQLAEVTVPLQMNLSSSTTSLITTSSRLAAMNVRSKPRSSTLSDPETRKHWVAKWTQSCMLLKRLIFESLLDQPSFFKWIIDQMKVANLAQIHFLLDIYHSVFERFNLSYNLVRGFVEACLFQIRFIAKQTATSYLSKLERRLKLAVQSAFTFCPDNFVWPDLWIPNKSLLQEIILADFLGDPDNSSLEQSSAPNQLREILTSDFYAVNWRVTELIGDVGIGTGIVGNIFTRRAQLVEILDSYSDYSDCSKLYYKYFLHPSVAGHISVSFKDKLEVLLSWATTLFRNSDKRVHLVASTLSYVKKDYKKNGDEFQNILVGWLEQIESTEGGDLLVRLFSELSRRNIFSYGAYVQRMVAKGDTECDILGGKASGVQALLSEWMPLASSRSSRERSNSIKRSPGRDFARNGLMAIIADFNSAIASADYGKFTSLLSRRLDARQPTSANRKLVAEILPKALVHLFSELAFVSVSGSPVSRTAHHPELASALLTWGFQLLESCQAYATLFEIMQRIVQIDLSRLEALRSDEGERTDLSLSFQSTFCYLQIICMSALNNKDIMEISGQLTDLVSRLFAIHFHFRRVVGGTSTAVRGFVRCLRNLVLESNDVDPQILEVLDKEYHPIFDEMTNGSMTGETLPSRTKEILQLLQCPSTEQVSLLVHKYWEAYRSDMDWGPALWNSLIAAIKIHSQEEFNELLVKNPDDSVQSPNDNMGEFREVLVQLCEDLDMLYEEGLIGCLIRAGYITYPHPDDEALFTRPAHASESKMTTEEEEGEENEGTSTAGQSLKDLFFHNPRSLCRNIRRLLLELMSSGLISIEVALEEYVIRPLADDVPQQLGSLYGDSSYDVTRVHQTIQVEEALRQVEEIHLLVNEVLCEPRVNRYSPGFSQSPDKESGVMMTPSRSRSDDHLSLMNQDTSDSSHRSKEVEYVIVDYVRTGRLDVERKLWFEQSEEGSAFCSRLLLSLLISMKTISELSFEPEVAENSAAQQPPPFEQLIPKILDAFESLREAVCQGSDLLRRQIPLQAAVFLDPILELVTKNDLGTIFHTKLIHSIDELLPYSQSSELVNHKYPYLESIFKESCIFNHAARTRQFQLHIRLLMSTNPPQMPMTKETPIDVASTLGALVEVMAKRLHLTDSKDAAPFFLDCLPLQVAEALIIKLSLYLGMSICKLLGPNSADSALEVLRIHHICRCITTLTNQLTIRTYQSSDDVASKVVGGCGPLGCNATIESYLSYWQQLKSGLTLLNSRLATSDPTTLSPRRMEYRIMRALLHSTQVVLWSLPGLTQQLGTLKQTIAEVWIEISLRVQGDSALQNQIMDTIGVLLFPTVPDDSCLTATVGILRKRFRWLYLPILNMDDGANLVPSNRLKYLLGCSLRGSSTIFQERPSDGAVKFLEEKPWEELEKMDVSGPGFISIDALKCQTLSHVEQIPEAKPSGSRQPKLKSGKSEGEDVLAEEIEPGGERGSDQPMGGLQHALNEDGGAEEEEEGPETGDRHSFEHELITDGLSTIPLHFLRSLYPPASRLLGTDWLVAVEQQKLEQAEQAEQTRSKQQQQQQQQQAANEGATEQNSGRLKKRKGVALSPSPAEQIGSSSSTGPTLRSARSTRKKSTAAAPANPPPTASSSKRVKKR
Length1859
PositionKinase
OrganismPuccinia coronata var. avenae f. sp. avenae
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Pucciniomycetes> Pucciniales> Pucciniaceae> Puccinia.
Aromaticity0.07
Grand average of hydropathy-0.285
Instability index54.93
Isoelectric point5.92
Molecular weight208813.40
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19236
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.19|      12|      27|    1173|    1184|       1
---------------------------------------------------------------------------
 1173- 1184 (22.61/15.19)	KLWFE.QSEEGSA
 1202- 1214 (15.58/ 7.78)	ELSFEpEVAENSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     287.61|      97|     288|     346|     453|       2
---------------------------------------------------------------------------
  346-  453 (144.79/140.58)	RGFVEACLFQI..RF...IAKQTATSYLSKLERRLKlAVQSafTFCPDNFVWPDLwipNKSLLQ...EIILADFLGDPDNsslEQSSAPNQLREILTSDF........YAVNWRVTELIgdVGI
  634-  746 (142.82/102.44)	RDFARNGLMAIiaDFnsaIASADYGKFTSLLSRRLD.ARQP..TSANRKLVAEIL...PKALVHlfsELAFVSVSGSPVS...RTAHHPELASALLTWGFqllescqaYATLFEIMQRI..VQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.17|      18|      19|    1686|    1703|       3
---------------------------------------------------------------------------
 1658- 1675 (26.99/13.73)	I.PEAK.PSGSRQPKLKSGK
 1686- 1703 (34.37/19.70)	I.EPGG.ERGSDQPMGGLQH
 1705- 1724 (20.81/ 8.73)	LnEDGGaEEEEEGPETGDRH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.19|      19|      19|    1763|    1781|       4
---------------------------------------------------------------------------
 1763- 1781 (30.00/18.76)	EQQKL.EQAEQAEQTRSKQQ
 1786- 1805 (25.19/14.40)	QQQAAnEGATEQNSGRLKKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.48|      41|     288|    1216|    1260|       5
---------------------------------------------------------------------------
 1216- 1260 (64.79/49.46)	QQPPPFEQLIPKILDAFeSLReavCQGSDLLRRQIPLQAAVFLDP
 1515- 1555 (70.69/42.44)	QQLGTLKQTIAEVWIEI.SLR...VQGDSALQNQIMDTIGVLLFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     306.00|     123|     288|    1018|    1155|       6
---------------------------------------------------------------------------
    5-   98 (111.87/57.88)	.........................................LIKPSR....lSHAQPPENQNAQPSSDKSPSSLDV...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................yqLQPPRwRLPTQLNR..PDLGYPGLHPTHIGqHEDAITKSLVQwGFSAQM..LVSTESFSA...HQMIY
  102-  170 (70.06/32.19)	TEETAFNVSSSAL...SALIEAR.RRYCA..MNSHDTKSTIKV.PGRvtlneQKRENWLRELADDSVPLLKLSKNV.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
 1020- 1084 (54.45/41.78)	............................................................................phgfkgekllemlvsrkiecsratwyirliglneinaqrnkndlshirytlsftpevcqflqkqlaevtvplqmnlsssttslittssrlaamnvrskprsstlsdpetrkhwvakwtqscmllkrlifeslldqpsffkwiidqmkvanlaqihflldiyhsvferfnlsynlvrgfveaclfqirfiakqtatsylsklerrlklavqsaftfcpdnfvwpdlwipnksllqeiiladflgdpdnssleqssapnqlreiltsdfyavnwrvteligdvgigtgivgniftrraqlveildsysdysdcsklyykyflhpsvaghisvsfkdklevllswattlfrnsdkrvhlvastlsyvkkdykkngdefqnilvgwleqiesteggdllvrlfselsrrnifsygayvqrmvakgdtecdilggkasgvqallsewmplassrssrersnsikrspgrdfarnglmaiiadfnsaiasadygkftsllsrrldarqptsanrklvaeilpkalvhlfselafvsvsgspvsrtahhpelasalltwgfqllescqayatlfeimqrivqidlsrlealrsdegertdlslsfqstfcylqiicmsalnnkdimeisgqltdlvsrlfaihfhfrrvvggtstavrgfvrclrnlvlesndvdpqilevldkeyhpifdemtngsmtgetlpsrtkeilqllqcpsteqvsllvhkyweayrsdmdwgpalwnsliaaikihsqeefnellvknpddsvqspndnmgefrevlvqlcedldmlyeegligcliragyityphpddealftrpahaseskmtteeeegeenegtstagqslkdlfFHNPR.SLCRNIRRllLELMSSGLISIEVA.LEEYVIRPLAD.DVPQQLgsLYGDSSYDVtrvHQTIQ
 1085- 1155 (69.62/47.12)	VEEALRQVEEIHLlvnEVLCEPRvNRYSPgfSQSPDKESGVMMTPSR.....SRSDDHLSLMNQDTSDSSHRSKEV.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.00|      12|      19|     921|     932|       8
---------------------------------------------------------------------------
  921-  932 (21.99/14.97)	EFNELLVKNPDD
  943-  954 (22.01/15.00)	EFREVLVQLCED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.61|      12|      19|    1826|    1837|      10
---------------------------------------------------------------------------
 1826- 1837 (19.95/13.45)	PTLRSARSTRKK
 1848- 1859 (19.66/13.14)	PTASSSKRVKKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.15|      30|     809|     459|     490|      12
---------------------------------------------------------------------------
  459-  490 (50.81/39.90)	GNIFtrRAQLVEILDSYSDYSDCSKL.YYKY.FL
 1271- 1302 (46.34/29.51)	GTIF..HTKLIHSIDELLPYSQSSELvNHKYpYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     177.81|      58|     479|     270|     337|      13
---------------------------------------------------------------------------
  270-  337 (85.69/97.72)	RSSTLSDPETRKHWVAKWTQS..CMLlkRLIFESLLDQPSFFKwIIDQMK..VANLAQIHFlldiyHsvFER
  750-  811 (92.11/69.56)	RLEALRSDEGERTDLSLSFQStfCYL..QIICMSALNNKDIME.ISGQLTdlVSRLFAIHF.....H..FRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.48|      12|      23|    1425|    1436|      15
---------------------------------------------------------------------------
 1425- 1436 (20.89/14.78)	LTNQLTIRTYQS
 1451- 1462 (21.59/15.56)	LGCNATIESYLS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19236 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FTRPAHASESKMTTEEEEGEENEGTSTAGQS
2) LGTDWLVAVEQQKLEQAEQAEQTRSKQQQQQQQQQAANEGATEQNSGRLKKRKGVALSPSPAEQIGSSSSTGPTLRSARSTRKKSTAAAPANPPPTASSSKRVKKR
3) NLIKPSRLSHAQPPENQNAQPSSDKSPSSLDVYQ
4) PGFSQSPDKESGVMMTPSRSRSDDHLSLMNQDTS
5) VEQIPEAKPSGSRQPKLKSGKSEGEDVLAEEIEPGGERGSDQPMGGLQHALNEDGGAEEEEEGPETGDRHSFEHELITDG
984
1754
4
1113
1655
1014
1859
37
1146
1734










Molecular Recognition Features






MoRF SequenceStartStop




1) ARSTRKKSTAAAPA
2) NSGRLKKRKGVALSPSPAE
3) PTASSSKRVKKR
1831
1798
1848
1844
1816
1859