Description | Uncharacterized protein |
Sequence | MDRLTQLQDAVDQLALQFVASIHFAHKRHDLEKLGPNDKIRSVKQEEEKEVDPLPEEEFRAGLLELSRDLILKEQQIEVLISTLPGLDSSERDQEQCIKELEEELKAAEEQRQDALKEKERVVGQLDKILKSVRRP |
Length | 136 |
Position | Middle |
Organism | Lomentospora prolificans |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Microascales> Microascaceae> Lomentospora. |
Aromaticity | 0.02 |
Grand average of hydropathy | -0.788 |
Instability index | 64.25 |
Isoelectric point | 4.87 |
Molecular weight | 15776.68 |
Publications | PubMed=28963165 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669 ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP19200 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 97.13| 33| 43| 56| 92| 1 --------------------------------------------------------------------------- 56- 92 (44.47/33.90) EEEFRAGllELSRDLILKEQqiEVLISTLPGLDSSER 102- 134 (52.65/28.68) EEELKAA..EEQRQDALKEK..ERVVGQLDKILKSVR --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) DALKEKERVVGQLDKILKSVR 2) PNDKIRSVKQEEEKEVDPLPEEEFRAGLLELSRDLILKEQQIEVLISTLPGLDSSERDQEQCIKELEEELKAAEEQR | 114 36 | 134 112 |
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