<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19199

Description Uncharacterized protein
SequenceMKEPLGDAINTGAKPSIFNKATGLFRKSHDEPTLPRYSDQIDPHDGHLHNGDATSSTINVPSNRASQEKKAAGATNDGRNPSVAEGAAVVPSQPGGDASASGEDPPERPKRTITQRFLHNCKSVILHSWVNVLLVFVPVGIAVEYVPGIHGGVVFAINCIAIVPLAGLLSHATESVAVKLGDTVGALLNVTFGNAVELIIFSIIALTKNKIRIVQASLLGSILSNLLLILGMCFFLGGLRFREQIYNSTVTQMSACLLSLSVISLVLPTAFHASFSDMDDADTESLKISRICSIILLLVYLVYLLFQLKSHSYMYESTPQHIVDAESTPGPAAAWLDTSSSDSSSSSSSSDSDDSDDSTPTVRKRMKRAIRRARRSSSSSNSSDSDGTANSKRTTNSKTLIGKASEAEASGSKAVGNDSSDDEVPKKRRHRHIRRKRSHKHKHERKDTENRAPETENSVRDASAPPVVVEEPPATADDTRRVDFAIQDDDNDDRRRASAGGNLASSNRRPFALRHVSVKNVRNLAPVLVQKPDASEVTPVSGPVPRVRYGIRRTNSLPDRLSQGYPVAHRAPGAMPAVHVPLISLTGGNAAEPAEHAIPEDRLSTVASVVLLLISTGLVALCAEFVVDSIEEVVEGGALRETFIGLIILPVVGNAAEHVTAITVAMKNKMDLAIGVAVGSSIQIALFVTPLVVILGWIMNKEMTLYFTLFETVCLFVSAFIVNFLVLDGRSNYLEGALLMCTYAIISVVAFYYPNVEDASELGGHSEFDIKLF
Length773
PositionKinase
OrganismLomentospora prolificans
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Microascales> Microascaceae> Lomentospora.
Aromaticity0.06
Grand average of hydropathy-0.033
Instability index49.25
Isoelectric point6.44
Molecular weight83121.52
Publications
PubMed=28963165

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
GO - Biological Process
transmembrane transport	GO:0055085	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19199
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     162.61|      31|      32|     343|     373|       1
---------------------------------------------------------------------------
  343-  373 (52.35/27.63)	SSSSSSSSDSDDSDDSTPTVR.KRMKRAIRRA
  376-  407 (40.56/19.96)	SSSSSNSSDSDGTANSKRTTNsKTLIGKASEA
  408-  435 (38.67/18.73)	EASGSKAVGNDSSDDEVP..K.KRRHRHIRR.
  438-  462 (31.04/13.77)	..SHKHKHERKDTENRAP.....ETENSVRDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.08|      26|      26|     566|     591|       2
---------------------------------------------------------------------------
  566-  585 (28.37/15.48)	.......PVAHR..............AP.GAMPAV.HVPLISL
  586-  614 (24.72/12.47)	TGGNAAePAEHA..............IPeDRLSTVaSVVLLLI
  615-  649 (19.99/ 8.57)	STGLVA......lcaefvvdsieevvEG.GALRET.FIGLIIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.22|      26|      32|     659|     688|       3
---------------------------------------------------------------------------
  659-  688 (35.18/37.30)	VTAITVAMKNKMDLAIGVAVGssiqIALFV
  692-  717 (46.03/35.91)	VVILGWIMNKEMTLYFTLFET....VCLFV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.12|      12|      34|     223|     234|       4
---------------------------------------------------------------------------
  223-  234 (19.65/11.53)	LSNLLLILGMCF
  246-  257 (17.47/ 9.51)	YNSTVTQMSACL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.46|      11|      25|     476|     487|       5
---------------------------------------------------------------------------
  476-  487 (15.55/16.95)	ADDTRRvDFAIQ
  504-  514 (19.91/15.11)	ASSNRR.PFALR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.03|      14|      17|     135|     148|       7
---------------------------------------------------------------------------
  135-  148 (25.25/15.05)	VFVPVGIAVEYVPG
  154-  167 (24.77/14.63)	VFAINCIAIVPLAG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19199 with Med13 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAWLDTSSSDSSSSSSSSDSDDSDDSTPTVRKRMKRAIRRARRSSSSSNSSDSDGTANSKRTTNSKTLIGKASEAEASGSKAVGNDSSDDEVPKKRRHRHIRRKRSHKHKHERKDTENRAPETENSVRDASAPPVVVEEPPATADDTRRVDFAIQDDDNDDRRRASAGGNLASSNRRPFALRHV
2) MKEPLGDAINTGAKPSIFNKATGLFRKSHDEPTLPRYSDQIDPHDGHLHNGDATSSTINVPSNRASQEKKAAGATNDGRNPSVAEGAAVVPSQPGGDASASGEDPPERPKRTI
333
1
516
113










Molecular Recognition Features






MoRF SequenceStartStop




1) DDEVPKKRRHRHIRRKRSHKHKHERK
2) NKATGLF
3) RRVDFAI
4) TPTVRKRMKRAIRRARRSSSS
421
19
480
359
446
25
486
379