<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19149

Description Uncharacterized protein
SequenceMAAFGLLSYEQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFSSILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLSVLAKKVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQPTDPNLEWTQISTRYLREQLAKISDFYHMASSSGDGPVPVPPEVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLTWILDVLEKIRPMDDDLLKLLLPLMLQYSDEFVQSAYLSRRLAYFCARRLSLLLSDSPNLLAAHSPHMMIGPNNSSIGAPSPGPPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWNYSTNENKSANPGSPLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVTISRVLHTLEVLDRHCFDRTDSSNSMETLYHKIFWPNQNKDNQEVAPNDEAVVTLLCEWAVSCKRSGKHRAMAVAKLLEKRQAEIEAERCGESEVLDEKESISSSSLAGSSLPVFQNVLLRFLDTQAPSLSDPNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTRPRSPAGENVDEHYSKDHDVKMEIFSPMPGESCENANTSLGRRMSVNCEKLVKREKPRELIFPSNYDLLRHLQYATHFPIPLDESSSHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTETGGGDEGQKARKNKQETFPTLETVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLMEPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTAQVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSKFGDLFSSACSKVKQTIYNNVMPANSNLRWDPDFMMDFIENPSARSINYSMLGKILSDNAANRYSFVCNTLMNVCMGHQDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSNHVWGFNDVLCTVDVSDLSFHDSLATFIAILIARQCFSLEDVVQHVALPSLLAAACGDADAEPGARMTCRLLLHLFRAPQACFLPQATGKPFPGIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMMLGDAKIGNNSVSSLKNDDFTMRGLRCDGNADDIWTASQNPKSCGKSISIETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLICYPHGIKECAEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPGSGSVAEMNNLLDNIAKATIEVFQQSAELNNNSSNSGMSLFNPNSIGSADTSSTRQNGIKTFLSSSERRGVWLVAPLIARLPTSVQGRVLKAAGEELEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQDDIKARQMMHEALQLRLNLVGGMFDTVQKSTQWTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSNASPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVQQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHLLLYHTHPKPKPRSYYLEPLPLPPEEEEEEPTSPVSQEPERKSAELSDQGKTTTDEEKKTKGRKRKTKSSSRVDEYPQSNIYRVPPNYSPISSQMMHHPQSTLWGYNLVGQPQQPGFFLQNQSLTPGGSRLDPAGSFVPTNTKQALSNMLQRRSGAMMQPPSLHAITSQQQLIQMKLLQQQQQQRLLRQAQTRPFQQGQPGDQAPLFAAQARPSPQLPQYPGLQQAQTMPQGYTMYGTQMPLQQTSQQQAGSVVLSPSYNSRAYSAAHSNPVLMERLRQIQQQPSGYVQQQASPYLQPLTGSQRLNHQALQQNPLVGGGIDAVLTSAHPNLPSVPLPQDPMRPRQPQVRQQQRILQMQQPQPQQPPQPQQSSQPQSQTLGLQAMQSQQPLFPRQGLQQTQQQQQTAALVRQLQKQLSSNQPQQGVTPYGHPSHF
Length2143
PositionKinase
OrganismSaimiri boliviensis boliviensis (Bolivian squirrel monkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Platyrrhini> Cebidae> Saimiriinae> Saimiri.
Aromaticity0.07
Grand average of hydropathy-0.438
Instability index57.60
Isoelectric point7.89
Molecular weight239832.45
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19149
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     706.05|     183|     203|    1741|    1942|       1
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 1589- 1724 (190.23/106.60)	.S.PGGSE.ENKRAYMN.....LVKKLKKELGDKR.....SESID........KV...............Q......QLLPLPKQ.............TC..DVITCEPMGSLIDTKGnKIAGFDSIDKKQG....LQ........VSTKQKVSPWDLFEGQK........NPAPLSWAWFGtvrvdrrvikyeE....QHHLLLYHTHPKPK...............PRSY
 1741- 1942 (299.20/214.36)	TS.PVSQEPERKSAELSdqgktTTDEEKKTKGRKRKTKS.SSRVDEYPQSNiyRVppnysPISSQMMHHPQstlwgyNLVGQPQQPGFFLQNQS...LTP..GGSRLDPAGSFVPTNT.KQALSNMLQRRSG..AMMQP..PSLHAITSQQQLIQMKLLQQQQQQRLLRQAQTRPFQQGQPG............D....QAPLFAAQARPSPQlPQYP..GLQQAQTMPQGY
 1947- 2113 (216.62/122.71)	TQmPLQQTSQQQA..................GSVVLSPSyNSRAYSAAHSN.........PVLMERLRQIQ............QQPSGYVQQQAspyLQPltGSQRLN...........HQALQQNPLVGGGidAVLTSahPNLPSVPLPQDPMRPRQPQVRQQQRILQMQQPQPQQPPQPQ............QssqpQSQTLGLQAMQSQQ.PLFPrqGLQQTQQQQQ..
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.62|      34|      44|     882|     923|       2
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  882-  916 (56.79/57.97)	CIVAVLRR.YHSCLILNpDQTAQVFEGLCGVVKHVV
  927-  961 (55.82/33.21)	CILAYLYDlYVSCSHLR.SKFGDLFSSACSKVKQTI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     215.65|      70|     203|     979|    1078|       3
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  979- 1072 (113.62/114.72)	MM..DF.IENPSARSI...NYSMLGkiLSDNaanrysfvcntlmnvcmghqdaGRINDIANFSSELTACCTVLSSEWLG.......VLKALCCS...SNHVWGFNDVLCT
 1184- 1269 (102.03/54.26)	MMlgDAkIGNNSVSSLkndDFTMRG..LRCD......................GNADDIWTASQNPKSCGKSISIETANlreyaryVLRTICQQewvGEHCLKEPERLCT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.55|      37|     203|    1276|    1318|       5
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 1279- 1318 (44.99/39.28)	LSNMQAQKLLQLicyphgIKECAEGDNLQ.RQHIKRILQ...NL........
 1460- 1497 (53.39/30.17)	MSLLSQQPFLSL......VLTCLKGQDEQ.REGLLTSLQ...NQ....vNQI
 1498- 1534 (32.16/15.01)	LSNWREERY...............QDDIKaRQMMHEALQlrlNLvggmfDTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.88|      39|    1057|     325|     369|      11
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  325-  369 (65.87/48.68)	NNSSIGAPSPGppgpgmSPVQLAFSDFLSCAQH......GPLVYGLSCMLQ
 1383- 1427 (60.01/31.22)	NPNSIGSADTS......STRQNGIKTFLSSSERrgvwlvAPLIARLPTSVQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19149 with Med12 domain of Kingdom Metazoa
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