<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP19013

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPK
Length1235
PositionTail
OrganismRhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Colobinae> Rhinopithecus.
Aromaticity0.10
Grand average of hydropathy-0.015
Instability index43.33
Isoelectric point7.06
Molecular weight141122.27
Publications
PubMed=25362486

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP19013
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.84|      14|      43|     331|     358|       1
---------------------------------------------------------------------------
  331-  354 (19.27/42.92)	GTSQLLWqhlssqliffVLFQFAS
  374-  387 (28.56/12.36)	GRDHLMW..........VLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.73|      28|      43|     607|     635|       2
---------------------------------------------------------------------------
  607-  635 (48.25/33.42)	LHTLLEMFSYRM......HHIQPHYrVQLLSHLHT
  647-  680 (42.48/24.40)	LHLCVESTALRLitalgsSEVQPQF.TRFLSDPKT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     194.41|      47|      49|     200|     248|       3
---------------------------------------------------------------------------
  148-  194 (51.23/33.05)	.IPNTVSSAVVQQLL.AARevIAYILERnaC.LLPAY...FAVTEIRKLYPEG.
  200-  248 (77.08/63.93)	LLGNLVSDFVDTFRP.TAR..INSICGR..CsLLPVVnNSGAICNSWKLDPATL
  252-  294 (66.10/45.07)	LKGLLPYD.KDLFEPqTAL..LRYVLEQ......PY..SRDMVCNMLGLNKQTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.68|      38|      90|    1069|    1109|       4
---------------------------------------------------------------------------
 1069- 1109 (67.91/53.95)	PdDTYYCRLIGRLVDTMAgkSPGPFPNCDW...RFNEFPNPAAH
 1163- 1203 (67.77/42.64)	P.EPYWIVLHDRIVSVIS..SPSLTSETEWvgyPFRLFDFTACH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.39|      51|     717|      22|      89|       5
---------------------------------------------------------------------------
   29-   89 (84.04/85.94)	TPEDEKTKLISCL.GAFRQF........................WGGLSQESHeqciqwIVKFIHGQHSPKrisfLYDCL..AMAVET
  729-  806 (77.35/41.73)	TPHNWASHTLSCFpGPLQAFfkqnnvpqesrfnlkknveeeyrkWKSMSNEND......IITHFSMQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.85|      26|     523|     409|     434|      11
---------------------------------------------------------------------------
  409-  434 (50.88/30.09)	YPEKEYI........PVPDINKPQSTHAFAMTCI
  934-  967 (44.96/25.75)	YPEKLYFeglaeqvdPPVQIQSPYLPIYFGNVCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.30|      16|      16|    1001|    1016|      12
---------------------------------------------------------------------------
 1001- 1016 (31.26/19.71)	YKFHDRPVTYLYNTL.H
 1018- 1034 (25.03/14.36)	YEMHLRDRAFLKRKLvH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP19013 with Med23 domain of Kingdom Metazoa
Unable to open file!