<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18964

Description Mediator complex subunit 25
SequenceMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTENLVQQIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPTDVSQDPRHMVLVRGLVLPVGGGSAPGPLQPKQPVPLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPPLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQQRGIGGQQAPPGLGPILEDQARPSQNLLQLRPPQSQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGTASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI
Length747
PositionUnknown
OrganismRhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Colobinae> Rhinopithecus.
Aromaticity0.05
Grand average of hydropathy-0.246
Instability index60.56
Isoelectric point8.61
Molecular weight78134.77
Publications
PubMed=25362486

Function

Annotated function 
GO - Cellular Component
nucleoplasm	GO:0005654	IEA:Ensembl

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18964
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     158.92|      37|      37|     308|     344|       2
---------------------------------------------------------------------------
  314-  351 (66.51/15.70)	PGVGPPFSQAPAPPLPPGPPGAPKPPPASQPsLVSTVA
  608-  639 (48.51/ 9.07)	QGTAQ.....PPPGAPQGPPGTASGPPPPGP.ILRPQN
  640-  671 (43.90/ 7.37)	PGANPQLRSLLLNP.PPPQTGVP.PPQASLH.HLQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     289.08|      41|     111|     249|     289|       3
---------------------------------------------------------------------------
  176-  232 (45.81/ 9.31)	RGIHFSivsprklpalrllfekAAPPALLEP.LQPPTDVSQD.PRHMVLVRGLV....lPVG.....G
  253-  298 (59.78/14.99)	SGATLS................AAPQQPLPP.VPPQYQVPGNLSAAQVAAQNAVeaaknQKA.....G
  366-  395 (38.48/ 6.33)	SMAG.T................VAPGGVSGP.SPAQ......LGAPALGGQQSV..............
  557-  598 (48.60/10.44)	RGIGGQ................QAPPG.LGPiLEDQARPSQNL.L.QLRPPQSQ.....P..qgtvgA
  673-  701 (44.30/ 8.69)	........................PGAP.AL.LPPPHQ...GLGQPQLGPPLLH.....PPP.....A
  702-  735 (52.10/11.86)	QSWPAQ................LPPRA...P.LPGQMLLSGG.PRGPVPQPGLQ.....P........
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18964 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGSAPGPLQPKQPVPLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPPLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALG
2) HKQVQQQKLEQQQRGIGGQQAPPGLGPILEDQARPSQNLLQLRPPQSQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGTASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMD
232
544
390
745










Molecular Recognition Features






MoRF SequenceStartStop




1) LMDLI
743
747