<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18826

Description Uncharacterized protein
SequenceMTAAPASPQQIRDRLLQAIDPQSNIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQNEAALRGLAGAAGSANGGAHNCRPEAGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGIGGSPESFPSPLDGSGHGSPEGSRLERGENDRHSSKIPVNAVRPHTSSPGLSKPPGPCLQGKASVLQQLDRVEETPGAPHPKGPPRCSYSPRNSRHEGSFARQQSPYASKGSVPSPSPRPQALDAAQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLAGLGCKAGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPPRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRRGARKLHVLVPHGPPTDLPGVTREVTEDDLDRIQAHQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length600
PositionUnknown
OrganismPropithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Strepsirrhini> Lemuriformes> Indriidae> Propithecus.
Aromaticity0.04
Grand average of hydropathy-0.864
Instability index63.30
Isoelectric point9.44
Molecular weight65405.69
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18826
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     492.27|     105|     108|     139|     245|       1
---------------------------------------------------------------------------
  126-  240 (173.52/65.45)	D.LKNrndiqrlpgQRLDRLgsRK..............................RRGDQRD........LGHPGPPP...KVS....KASHD.PLVPNSSPLPTNGIGGSPESFPSPLDG.SGHG.SP..EGSRLERGENDRHSSKIPVNAVR..PHTSSP..GLSKPP..G
  241-  347 (129.64/44.59)	PCLQG....kasvlQQLDRV..EE..............................TPGAP............HPKGPP...RCSysprNSRHEgSFARQQSPYASKGSVPSPSPRPQALDA.AQVP.SP......LPLAQ....PSTPPVRRLEllPSAESPvrWLEQPE..G
  393-  487 (90.52/28.73)	......................KK..............................KRYRPRDytvnldgqVAEAGVKPvrlKER....KLTFD.PMTRQIKPLTQK....EPVRADSPV.....HTeQP.......PRTELDKQEAKASLQSPF..EQTNWK..ELSRNEiiQ
  488-  596 (98.59/32.25)	SYLS....................rqssllsssgaqtpgahhfmseylkqeestRRG.ARK........L....................H..VLVPHG.P.PTDLPGVTREVTEDDLDRiQAHQ.WPgvNGCQDTQGNWYDWTQCISLD.....PHGDDG..RLNILP..Y
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.79|      29|     252|      88|     123|       2
---------------------------------------------------------------------------
   88-  123 (39.61/35.23)	HQNeaaLRGLAGAAGSAngGAHNCRPEAGVagAPKS
  348-  376 (56.19/28.41)	HQR...LAGLGCKAGLP..PAEPLLPRAGF..SPDS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18826 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EAALRGLAGAAGSANGGAHNCRPEAGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGIGGSPESFPSPLDGSGHGSPEGSRLERGENDRHSSKIPVNAVRPHTSSPGLSKPPGPCLQGKASVLQQLDRVEETPGAPHPKGPPRCSYSPRNSRHEGSFARQQSPYASKGSVPSPSPRPQALDAAQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPEGHQRLAGLGCKAGLPPAEPLLPRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGV
2) PVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHTEQPPRTELDKQEAKASLQSPFEQTNW
3) RRGARKLHVLVPHGPPTDLPGVTREVTEDDLDRIQAHQWP
91
417
522
415
477
561










Molecular Recognition Features






MoRF SequenceStartStop




1) IRDRLL
2) RRLELL
3) SKKKKRYRPRDYTVNLDGQ
11
327
391
16
332
409