<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18773

Description Mediator complex subunit 25
SequenceMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGYTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPADVSQDPRHMVLVRGLVLPVGGGSASGPLQPKQPVPLPPTAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGAPFSQASAPPLPPGPPGAPKPPPASQPSLVSTVAPGPGLAPSAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGGQQAPPGLGPILEDQARPSQNLVRTESQRLPFMPTWGCGGPGTVGASGATGQPQPQGTTQAPPGAPQGPPGAAPGQPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPSRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI
Length754
PositionUnknown
OrganismPropithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Strepsirrhini> Lemuriformes> Indriidae> Propithecus.
Aromaticity0.06
Grand average of hydropathy-0.229
Instability index57.58
Isoelectric point8.72
Molecular weight78840.57
Publications









Function






Annotated function


GO - Cellular Component
nucleoplasm	GO:0005654	IEA:Ensembl

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18773
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     149.40|      30|      30|     660|     689|       1
---------------------------------------------------------------------------
  311-  340 (50.30/12.37)	QAAPGVGAPFSQASAPPLPpgPPGA...PK..PPP
  660-  687 (56.45/14.97)	PPPPQTGVPPPQASLHHLQ..PPGA...PALLP..
  688-  718 (42.64/ 9.13)	..PPHQGLGQPQLGPPLLH..PPPAqswPAQLPSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.81|      22|      22|     228|     249|       3
---------------------------------------------------------------------------
  230-  252 (37.31/10.07)	VGGGSASGPLQPKQPVPLPPtAP
  253-  273 (33.25/ 8.00)	SGATLSAAPQQPLPPV..PPqYQ
  603-  625 (31.24/ 6.97)	VGASGATGQPQPQGTTQAPPgAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     201.06|      54|      67|      76|     130|       4
---------------------------------------------------------------------------
   41-   74 (26.27/ 8.61)	......................LPAIEYFNGGPPAETDFGgdyGGTQYSLVVFNTV..
   76-  130 (90.60/52.78)	CAPESYVqCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIA...EGLSTALQLFDDFKK
  146-  197 (84.19/44.92)	CNSPPYL.LPAVESTTYSGYTTESLVQKIGERGIHFSIVS...PRKLPALRLL..FEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.51|      26|      26|     471|     496|       6
---------------------------------------------------------------------------
  471-  496 (45.95/38.15)	VQF.HFTNKDLESLKGLYRIMGNGFAG
  498-  524 (37.56/29.63)	VHFpHTAPCEVRVLMLLYSSKKKIFMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.02|      28|     427|     200|     228|       7
---------------------------------------------------------------------------
  200-  228 (47.80/23.52)	PPAlLEPLQPPAD...VSQDPRHMVLVRGLVL
  628-  658 (50.22/21.38)	PPG.AAPGQPPPGpilRPQNPGANPQLRSLLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18773 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSASGPLQPKQPVPLPPTAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGAPFSQASAPPLPPGPPGAPKPPPASQPSLVSTVAPGPGLAPSAQPGAPSMAGTVAPGGVSGPSPAQLGAPALG
2) HKQVQQQKLEQQRGMGGQQAPPGLGPILEDQARPSQNLVRTESQRLPFMPTWGCGGPGTVGASGATGQPQPQGTTQAPPGAPQGPPGAAPGQPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPSRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMD
233
544
390
752










Molecular Recognition Features






MoRF SequenceStartStop




NANANA