<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18623

Description Uncharacterized protein
SequenceIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPAHQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFPGSLDGSGHAGPEGGRLERGENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQTNWKELSRNEIIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLKQEESTRQGARQLHVLVPQSPPTDLPGLTRDITQDDLDRIQASQWPGVNGCQDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length576
PositionUnknown
OrganismMandrillus leucophaeus (Drill) (Papio leucophaeus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Cercopithecinae> Mandrillus.
Aromaticity0.04
Grand average of hydropathy-0.872
Instability index61.75
Isoelectric point9.41
Molecular weight62816.77
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18623
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     557.39|     119|     120|     194|     312|       1
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   85-  189 (86.86/21.44)	...........HNCRPEVG.AA..GP...PR.SIhdLksrndlqrlpgQRLDRLGSrkrrgdqrdlgHPGPP.PKvskashDPlvPNSSPLPTN...............................GISGSPES............................FPGSLDG...............SGHAGPEGGRLE...RGE
  194-  312 (220.79/62.93)	SGKIPINAVRPHTSSPGLGKPP..GPCLQPKASV..L...........QQLDRVDE...........TPGPPHPK......GP..PRCSFSPRNSRHE.......GSFARQQSLYAPK.......GSVPSPSP............................RPQALDATQVP.SPL.....PLAQPSTPPVRRLELLPSAE
  314-  422 (110.69/28.82)	....PVRWLEQPESHQRLA.GP..G.C...KAGL.................................SPAEPLL...........SRAGFSPDSSKADsdaassgGSDSKKKKRYRPRdytvnldGQVAEAGV............................KPVRLKERKLTfDPMtrqikPLTQ..KEPVR.......AD
  439-  571 (139.05/37.60)	EAKASLQSPFEQTNWKELSRNEiiQSYLSRQSSL..L...........SSSG..AQ...........TPGAHHFM......SE.....YLKQEESTRQ.......G..ARQLHVLVPQ........SPPTDLPgltrditqddldriqasqwpgvngcqdtQGNWYDWTQCI.SLD.....PHGDDG.....RLNILP...
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18623 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HQHEAALRGLAGATGSANGGAHNCRPEVGAAGPPRSIHDLKSRNDLQRLPGQRLDRLGSRKRRGDQRDLGHPGPPPKVSKASHDPLVPNSSPLPTNGISGSPESFPGSLDGSGHAGPEGGRLERGENDKHSGKIPINAVRPHTSSPGLGKPPGPCLQPKASVLQQLDRVDETPGPPHPKGPPRCSFSPRNSRHEGSFARQQSLYAPKGSVPSPSPRPQALDATQVPSPLPLAQPSTPPVRRLELLPSAESPVRWLEQPESHQRLAGPGCKAGLSPAEPLLSRAGFSPDSSKADSDAASSGGSDSKKKKRYRPRDYTVNLDGQVAEAGV
2) PVRLKERKLTFDPMTRQIKPLTQKEPVRADSPVHMEQQSRTELDKQEAKASLQSPFEQ
3) RQGARQLHVLVPQSPPTDLPGLTRDITQDDLDR
64
393
498
391
450
530










Molecular Recognition Features






MoRF SequenceStartStop




1) KKKKRYRPRDYTVNL
2) VRRLELLP
368
302
382
309