<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP18565

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVVSAAASHPGLRMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQVLYYHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDNILFIFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPVNAYRMQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
Length1324
PositionTail
OrganismMandrillus leucophaeus (Drill) (Papio leucophaeus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Cercopithecinae> Mandrillus.
Aromaticity0.10
Grand average of hydropathy0.017
Instability index44.31
Isoelectric point7.97
Molecular weight151374.70
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP18565
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     364.25|     147|     213|     137|     302|       1
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  137-  244 (100.33/74.69)	.......................................................................................................LLKVILEKILTIPNTVSSavVQQLLAAREVI...........AYI...LERNAclLPAYFAVTEIRK.LYPEGKLPHwllgnlVSDfVDTFRPTARINSICGRCSLLPVVNNSGAicnswKLD
  245-  448 (219.10/111.12)	PATLRFPLKGLlpyDKDLFEPQTALLRY...VLEQPYSRDMVCNMLGLNKQV..LYYHK.QRCPvledqlvdlvvyamerseteekfddggtsqllwqhlssqLIFFVLFQFASFPHMVLS..LHQKLAGRGLIkgrdhlmwvllQFIsgsIQKNA..LADFLPVMKLFDlLYPEKEYIP......VPD.INKPQSTHAFAMTCIWIHLNRKAQNDNS.....KLQ
  452-  512 (44.82/13.19)	PHSLRLHHEFL...QQSLRNKSLQMNDYkiaLLCNAYSTNSECFTLPMGALVetIYGNGiMRIP..................................................................................................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.11|      13|      17|    1042|    1057|       2
---------------------------------------------------------------------------
 1042- 1055 (24.76/19.93)	RPQG.WCLSDTYLkC
 1060- 1073 (24.35/ 8.39)	REENpWVPDDTYY.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.00|      15|      20|     983|    1002|       3
---------------------------------------------------------------------------
  983- 1002 (18.08/25.32)	PVSKSLETLldHlggLYKFH
 1005- 1019 (30.92/19.43)	PVTYLYNTL..H...YYEMH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     133.97|      46|     611|     514|     565|       7
---------------------------------------------------------------------------
  514-  565 (73.21/60.03)	PGTNC...M.ASG.SITPLPMNLLdSLTVHAKMSLIHSIAtrvikLAHA...KSSV...ALAP
 1128- 1184 (60.76/36.27)	PRENItawMnAIGlIITALPVNAY.RMQSYSEMSCSYTLA.....LAHAvwhHSSIgqlSLIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.24|      16|     207|     592|     615|       8
---------------------------------------------------------------------------
  592-  608 (25.20/27.07)	LLPTvFKSHAWGILHTL
  619-  634 (29.04/ 9.62)	IQPH.YRVQLLSHLHTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.63|      44|     716|      23|      73|      11
---------------------------------------------------------------------------
   23-   73 (72.03/67.41)	LRMFMD.TPEDEKTKLISCL.G.........................AFRQfWGGLSQESHeqciqwIVKFIHGQHSP
  720-  790 (62.61/39.75)	LQTIMSfTPHNWASHTLSCFpGplqaffkqnnvpqesrfnlkknveeEYRK.WKSMSNEND......IITHFSMQGSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.34|      17|      21|     898|     915|      12
---------------------------------------------------------------------------
  898-  915 (26.47/23.69)	NDFRNRVSDFVKENsPEH
  919-  935 (34.87/26.01)	NDWHTKHMNYHKKY.PEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.63|      16|      21|     936|     951|      13
---------------------------------------------------------------------------
  936-  951 (27.99/18.99)	LYFEGLAEQVDPPVQI
  958-  973 (29.64/20.59)	IYFGNVCLRFLPVFDI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP18565 with Med23 domain of Kingdom Metazoa
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